…From Single Molecules to Cells…
Fachbereich 14

Th. Dingermann, K. Hiller, G. Schneider, I. Zündorf (2004). Arzneidrogen (5. Auflage). Elsevier GmbH, Spektrum Akademischer Verlag, Heidelberg, ISBN 3-8274-1481-4

K. Szafranski, Th. Dingermann, G. Glöckner & Th. Winckler (2004). Template jumping by a Dictyostelium LINE reverse transcriptase created a SINE-like 5S rRNA retropseudogene. Mol. Gen. Genomics 271, 98-102

A. Rohmann, D. Lochmann, J. Weyermann, W.M. Bertling, T. Dingermann & A. Zimmer (2004). Rapid Screening Method for Antisense Oligonucleotides Against Human Growth Factor Receptor p185erb-2. Oligonucleotides 14, 1-9

A. Bursen, S. Moritz, A. Gaussmann, T. Dingermann & R. Marschalek (2004). Interaction of AF4 wild-type and AF4.MLL fusion protein with SIAH proteins: indication for t(4;11) pathobiology? Oncogene 23, 6237-6249

T. Winckler, N. Iranfar, P. Beck, I. Jennes, U. Baik, W.F. Loomis & T. Dingermann (2004). CbfA, the C-module DNA-binding factor, plays an essential role in the initiation of Dictyostelium discoideum development. Euk. Cell 3, 1349-1358.

K.M.G. Brand, C. Klein, I. Zündorf, T. Dingermann & W. Knöss (2004). Generation and Characterization of Monoclonal Antibodies to Oleanolic Acid. Planta Med. 70, 986-992.

B. Classen, M. Csávás, A. Borbás, T. Dingermann & I. Zündorf (2004). Monoclonal Antibodies against an Arabinogalactan-Protein from Pressed Juice of Echinacea purpurea. Planta. Med. 70, 861-865.

T.M. Böhme, C. Klein, K. Kreutzmann, M. Linder, Th. Dingermann, G. Dannhardt, E. Mutschler, G. Lambrecht (2003). Structure-activity relationships of dimethindene derivatives as new M2-selective muscarinic receptor antagonists. J. Med. Chem., 46, 856-867

D. Schraets, Th. Dingermann, R. Marschalek (2003). MLL mediated transcriptional gene regulation investigated by gene expression profiling. Oncogene 22, 3655-3668

M. Wurglics, S. Schulte-Löbbert, Th. Dingermann, M. Schubert-Zsilavecz (2003). Rationale und traditionelle Johanniskrautpräparate: Konsequenzen für die Depressionsbehandlung. Deutsche Apotheker Zeitung 143, 1454-1458

Th. Dingermann, D. Loew (2003). Phytopharmakologie: Experimentelle und klinische Pharmakologie pflanzlicher Arzneimittel. Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, ISBN 3-8047-1896-5

A. Lühe, H. Hildebrand, U. Bach, Th. Dingermann, H.J. Ahr (2003). A New Approach to Studying Ochratoxin A (OTA)-Induced Nephrotoxicity: Expression Profiling in Vivo and in Vitro Employing cDNA Microarrays. Toxicol Sci 73, 315-328

Th. Dingermann (2003). Kein Aut-idem bei Phytopharmaka. Geriatrie Journal 7-8/2003, 10-12

J.H. Keller, M. Karas, W.E. Müller, D.A. Volmer, G.P. Eckert, M.A. Tawab, H.H. Blume, Th. Dingermann, M. Schubert-Zsilavecz (2003). Determination of Hyperforin in Mouse Brain by High-Performance LIquid Chromatography/Tandem Mass Spectrometry. Anal. Chem. 75 (22), 6084-6088

K. Fucke, C. Kreienkamp, F. Rezai, S. Steube & Th. Dingermann (2003). Interaktionen mit Phytopharmaka. Prisma 10, 266-27

Th. Dingermann & I. Zündorf (2002). Verheißungen für die Therapie: Embryonale Stammzellen. ÖAZ 56, 760-765

A. Friese, K. Hell-Momeni, I. Zündorf, T. Winckler, T. Dingermann & G. Dannhardt (2002). Synthesis and biological evaluation of cycloalkylidene carboxylic acids as novel effectors of Ras/Raf interaction, J. Med. Chem. 45, 1535-1542

P. Beck, Th. Dingermann & T. Winckler (2002). Transfer RNA gene-targeted retrotransposition of Dictyostelium TRE5-A into a chromosomal UMP synthase gene trap, J. Mol. Biol.318, 273-285

G. Glöckner, L. Eichinger, K. Szafranski, J.A. Pachebat, A.T. Bankier, P.H. Dear, R. Lehmann, C. Baumgart, G. Parra, J.F. Abril, R. Guigó, K. Kumpf, B.Tunggal, the Dictyostelium Genome Sequencing Consortium (u.a. T. Dingermann & T. Winckler), E. Cox, M.A. Quail, M. Platzer, A. Rosenthal & A.A. Noegel (2002). Sequence and analysis of chromosome 2 of Dictyostelium discoideum, Nature 418, 79-85

Th. Dingermann (2002). Gewaltige Verheißungen: Embrynale Stammzellen, Heilsbringer für die Medizin? Forschung Frankfurt 3/2002, 24-30

T. Winckler, T. Dingermann & G. Glöckner (2002). Dictyostelium mobile elements - strategies to amplify in a compact genome (Review), Cell. Mol. Life Sci. 59, 2097-2111

D. Albert, I. Zündorf, Th. Dingermann, W.E. Müller, D. Steinhilber, O. Werz (2002). Hyperforin is a dual inhibitor of cyclooxygenase-1 and 5-lipoxygenase. Biochemical Pharmacology 64, 1767-1775

K. Beyreuther, H.K. Biesalski, Th. Dingermann, H. Kretzschmar, G. Multhaup, J. Tatzelt, G. Wolfram (2002). Hohenheimer Konsensusgespräch "BSE". Aktuel. Ernaehr. Med. 27, 304-314

K. Dannat, J. Tillner, Th. Winckler, M. Weiß, K. Eger, Th. Dingermann (2003). Effects of medicinal compounds on the differentiation of the eukaryotic microorganism Dictyostelium discoideum: Can this method be used as a screening test for reproductive toxicity in humans? Pharmazie, 58, 204-210

G. Glöckner, K. Szafranski, T. Winckler, T. Dingermann, M. Quail, E. Cox, L. Eichinger, A.A. Noegel & A. Rosenthal (2001). The complex repeats of Dictyostelium discoideum, Genome Res. 11, 585-594

T. Winckler, C. Trautwein, C. Tschepke, C. Neuhäuser, I. Zündorf, G. Vogel & T. Dingermann (2001). Gene function analysis by amber stop codon suppression: CMBF is a nuclear protein that supports growth and development of Dictyostelium amoebae, J. Mol. Biol. 305, 703-714

Th. Dingermann (2001). BSE: Konsequenzen für die Arzneimittelsicherheit. Forschung Frankfurt 3/2001, 27-32

Th. Dingermann (2001). Embryonale Stammzellen: Gewaltige Verheißungen für die Therapie. Pharm.Ztg. 34, 2894-2899

I. Zündorf, Th. Dingermann (2001). Vom Rinder-, Schweine-, Pferde-Insulin zum Humaninsulin: Die biotechnische und gentechnische Insulin-Herstellung. Pharm. unserer Zeit 30, 27-32

U. Hentschel, I. Zündorf, T. Dingermann & T. Winckler (2001). On the problem of establishing the subcellular localization of Dictyostelium retrotransposon TRE5-A proteins by biochemical analysis of nuclear extracts,  Anal. Biochem. 296, 83-9

I. Zündorf, Th. Dingermann (2001). Struktur des HI-Virus. Pharm. unserer Zeit 30, 203 - 207

E. Reinhard, Th. Dingermann, W. Kreis, H. Rimpler (2001). Pharmazeutische Biologie: Die biologischen Grundlagen für Studium und Praxis. Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, ISBN 3-8047-1785-3

K.M. Pang, Th. Dingermann & D.A. Knecht (2001). Regulated expression of myosin II heavy chain and RacB using an inducible tRNA suppressor gene, Gene 277, 187-197

Th. Dingermann, E. Giger & M.H. Kreuter (2001). Black Cohosh. Food Processing Japan 36, 60-62

Dingermann, Th. (Hrsg.) unter Mitarbeit der Expertenkommission BARMER/BPI (2000). Transparenzkrierien für pflanzliche, homöopathische und anthroposophische Arzneimittel. Expertenvotum zur Vorbereitung eines Modellvorhabens nach §§ 63 - 65 SGB V zur Förderung der Rationalität der Verordnung pflanzlicher, homöopathischer und anthroposophischer Arzneimittel. Karger GmbH, Basel, Freiburg, Paris.

Dingermann, Th. (2000). Wie gefährlich ist die Gentechnik? In: Pharmazeutische Biotechnologie. Kompendium für Forschung und Praxis, O. Kayser & H. Müller (Hrsg.). Wissenschaftliche Verlagsgesellschaft, Stuttgart, pp. 369 - 384.

Zündorf, I., and Dingermann, Th. (2000). Neue gentechnisch hergestellte Arzneimittel. Pharm. unserer Zeit 29, 167 - 173.

Schlitzer, M., Sattler, I., Friese, A., Zündorf, I., and Dingermann, Th. (2000). Synthesis of 4-(acylaminomethyl)benzamides and their evaluation as potential anticancer agents. Anticancer Res. 20, 1723 - 1726

Dingermann, Th., and Morck, H. (2000). Gezielte Therapie mit Hightech-Arzneimitteln. Pharm. Ztg. 49, 4187 - 4190

S. Henke, A. Rohmann, W. M. Bertling, T. Dingermann, and A. Zimmer (2000). Enhanced in vitro oligonucleotide and plasmid DNA transport by VP1 virus-like particles. Pharmaceutical Research 17, 1062-1070.

Wolf, H.-T., van den Berg, Th., Czygan, F.-C., Mosandl, A., Winckler, Th., Zündorf, I., and Dingermann, Th. (1999). Identification of Melissa officinalis subspecies by DNA fingerprinting. Planta Med. 65, 83-85

Wolf, H.-T., Zündorf, I., Winckler, Th., Bauer, R., and Dingermann, Th. (1999). Characterization of Echinacea species and detection of possible adulterations by RAPD analysis. Planta Med. 65, 773-774

Horn, J.,  Dietz-Schmidt, A., Zündorf, I., Garin, J., Dingermann, T., and Winckler, T. (1999). A Dictyostelium protein binds to distinct oligo(dA)•oligo(dT) DNA sequences in the C-module of the retrotransposable element DRE. Eur. J. Biochem. 265, 441-448

Szafranski, K., Glöckner, G., Dingermann, T., Dannat, K., Noegel, A.A., Eichinger, L., Rosenthal, A., and Winckler, T. (1999). Non-LTR retroelements with unique integration preferences downstream of Dictyostelium discoideum transfer RNA genes. Mol. Gen. Genet. 262, 772-780

Dingermann, Th. (1999). Stoffproduktion durch gentechnisch veränderte Organismen. In: Arzneidrogen, G. Schneider & K. Hiller (Hrsg.), Spektrum Aksdemischer Verlag, Heidelberg, Berlin, pp. 55 - 66.

Dingermann, Th. (1999). Essential similarity bei Phytopharmaka. In: Phytopharmaka V: Forschung und klinische Anwendung, D. Loew, H. Blume & Th. Dingermann (eds), Steinkopff Verlag, Darmstadt, pp. 27-33

Dingermann, Th., Zündorf, I. (1999). Gentechnik - Biotechnik . Lehrbuch und Kompendium für Studium und Praxis. Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, ISBN 3-8047-1597-4

Tillner, J., Nau, H., Winckler, Th. and Dingermann, Th. (1998). Evaluation of the teratogenic potential of valproic acid analogues in the eucaryotic microorganism Dictyostelium discoideum . Toxicol. In Vitro 12, 463-469

Winckler, Th., Tschepke, Ch., de Hostos, E.L., Jendretzke, A. and Dingermann, Th. (1998). Tdd-3, a transfer RNA gene-associated poly(A) retrotransposon in the genome of Dictyostelium discoideum. Mol. Gen. Genet. 257, 655-661

Zündorf, I., Wiedenfeld, H., Röder, E. and Dingermann, Th. (1998). Generation and Characterization of Monoclonal Antibodies against the Pyrrolizidine Alkaloid Retrorsine. Planta Med. 64, 259-263

Tillner, J., and Dingermann, Th. (1998). Retinoide und Embryonalentwicklung: Molekulare Mechanismen der Teratogenität. Deutsche Apotheker Zeitung 138, 704-710

Dingermann, Th., and Zündorf, I. (1998). Das Immunsystem: Ziel und Quelle von Arzneistoffen. Teil 1: Komponenten des Immunsystem. Prisma 5, 28

Dingermann, Th., and Zündorf, I. (1998). Das Immunsystem: Ziel und Quelle von Arzneistoffen. Teil 2: Arzneistoffe mit Wirkung auf das Immunsystem. Prisma 5, 108-113

Dingermann, Th. (1998). Gentechnologie und Arzneimittel. Internist. Prax. 38, 711-726

Winckler, Th. (1998). Retrotransposable elements in the Dictyostelium discoideum genome. Cell. Mol. Life Sci. 54, 383-393

Van Rensen, I., Blume, H., Ihrig, M., Morck, H., Dingermann, Th., and Veit, M. (1998). Bewertung von Phytopharmaka in der Apothekenpraxis. Pharm. Z. 143, 561-569

Veit, M., van Rensen, I., Blume, H., Ihrig, M., Morck, H., and Dingermann, Th. (1998). Bewertung von Phytopharmaka in der Therapie der BPH. Pharm. Z. 143, 1905- 1927

Zündorf, I, and Dingermann, Th. (1998). Gentechnologie und Arzneimittel. PharmuZ 27, 223-232

Dingermann, Th. (1998). Gentechnisch hergestellte Arzneimittel. Apotheke und Krankenhaus 14, 78-84

Dingermann, Th. (1998). Gentechnologie und Arzneimittel. tägl. prax. 39, 711-726

Dingermann, Th. (1998). Pharmazeutische Qualität von Phytopharmaka. In: Phytotherapie bei Störungen und Erkrankungen des Nervensystems, S. Chrubasik & M. Wink (eds), Verlag M. Rheinheimer, Ludwigshafen, pp. 15-23

Dingermann, Th. (1997). Gentechnisch hergestellte Arzneistoffe: Eine neue Wirkstoffklasse mit neuen Herausforderungen an die Analytik und Bewertung. Pharm. Ind. 59, 348-351

Bukenberger, M., Horn, J., Dingermann, Th., Dottin, R.P. and Winckler, Th. (1997). Molecular cloning of a cDNA encoding the nucleosome core histone H3 from Dictyostelium discoideum by genetic screening in yeast. BBA 1352, 85-90

Zündorf, I., and Dingermann, Th. (1997). Bewertung der Qualität von Phytopharmaka. Deutsche Apotheker Zeitung 137, 3107-3118.

Dingermann, Th. (1997). Wie gefährlich ist die Gentechnik? PharmuZ 26, 192 - 198

Dingermann, Th. (1997). Phytopharmaka in der Dermatologie. Österreichische Apotheker Zeitung 51, 783-786

Morrison, A., Marschalek, R., Dingermann, Th., and Harwood, A.J. (1997). A novel, negative selectable marker for gene disruption in Dictyostelium. Gene 202, 171 - 176

Hösch G., Wiedenfeld, H., Dingermann, Th., and Röder, E. (1996). A new HPLC-method for the simultaneous quantitative analysis of pyrrolizidine alkaloids and their N-oxides in Senecio leucophyllus. Phytochemical Anal. 7, 284-288

Dingermann, Th. (1996). Gentechnisch modifizierte Nahrung. Was kommt auf uns zu? Praxismagazin med. 2/96, 52-54

Li, Z., Sommer, A., Dingermann, Th., and Noe, C.R. (1996). Molecular cloning and sequence analysis of a cysteine protease inhibitor of Sorgum bicolor seedlings. Mol. Gen. Genet. 251, 499-502

Dingermann, Th. (1996).Bovine Spongiforme Encephalopathie. Deutsche Apotheker Zeitung 136, 165

Geier, A., Horn, J., Dingermann, Th., and Winckler, Th. (1996). A nuclear protein factor binds specifically to the 3'-regulatory module of the long-interspersed-nuclear-element-like Dictyostelium repetitive element. Eur. J. Biochem., 241, 70-76

Toto, T., Adams, E.F., Fahlbusch, R., Dingermann, Th., Werner, H. (1996). Autocrine growth stimulation of human meningioma cells by platelet-derived growth factor. J Neurosurgery 84, 852-858

Dingermann, Th. (1996). BSE: Konsequenzen für die Arzneimittelsicherheit I. Bioforum 7-8, 298-301

Dingermann, Th. (1996). BSE: Konsequenzen für die Arzneimittelsicherheit II. Bioforum 9, 366-368

Tillner, J., Winckler, Th., and Dingermann, Th. (1996). Developmentally regulated promoters from Dictyostelium discoideum as molecular markers for testing potential teratogens. Pharmazie 51, 902-906

Dingermann, Th. (1996). Gentechnologie. In: Lehrbuch der Pharmazeutischen Biologie, R. Hänsel, J. Hölzl, (Hrsg.)., Springer-Verlag, Berlin, Heidelberg, New York, pp. 454 - 477

Kuspa, A., Dingermann, Th., and Nellen, W. (1995). Analysis of gene function in Dictyostelium. Experientia 51, 1116-1123

Voith, G., and Dingermann, Th. (1995). Expression of the human muscarinic receptor gene m2 in Dictyostelium discoideum. Nature Biotechnology 13, 1225-1229

Voith, G., and Dingermann, Th. (1995). Expression of CSA-hm2 fusion in Dictyostelium discoideum under the control of the Dictyostelium ras promoter reveals functional muscarinic receptors. Pharmazie 50, 758-762

Dingermann, Th. (1995). Gentechnische Modifikationen von Nahrungs- und Arzneipflanzen. Bioforum 18, 252-257

Dingermann, Th. (1995). Phytopharmaka im Alter. Pharmazeutische Zeitung 23, 9 -16

Schumann, G., Zündorf, I., Hofmann, J., Marschalek, R., and Dingermann, Th. (1994). Internally located and oppositely oriented Pol II promoters direct convergent transcription of the retrotransposon DRE from Dictyostelium discoideum. Mol. Cell. Biol. 14, 3074-3084

Bukenberger, M., Dingermann, T., Meissner, W., Seifart, K.H., and Winckler, Th. (1994). Isolation of transcription factor IIIC from Dictyostelium discoideum. Eur. J. Biochem. 220, 839-846

Dingermann, Th. (1994). Gentechnologie in der Pflanzenphysiologie: Eine Herausforderung für Wissenschaftler und Verbraucher. Österreichische Apotheker Zeitung 48, 389-395

Schumann, G., Zündorf, I., Schmidt, A., Marschalek, R., and Dingermann, Th. (1994). Characterization of transcripts from the Dictyostelium discoideum retrotransposable genetic element DRE. Pharmazie 49, 923-925

Tillner, J., Winckler, Th., and Dingermann, Th. (1994). A simple cytotoxicity assay using the eucaryotic microorgamism Dictyostelium discoideum. Pharmazie 49, 759-761

Adams, E.F., Dingermann, Th., Fahlbusch, R., Rafferty, B., Toto, T., Werner, H. (1994). Secretion of interleukin-6 by human meningioma cells: Possible autocrine inhibitory regulation of neoplastic cell growth. J Neurosurgery 81, 394-401

Dingermann, Th. (1994). Gentechnisch modifizierte Nahrung: Was kommt auf uns zu? Pharm. Z. 139, 3901-3908

Dingermann, Th. (1994). Molekularbiologie und Pharmazie. Deutsche Apotheker Zeitung 134, 4353-4360

Dingermann, Th. (1994). Gentechnische Herstellung von Insulin. Deutsche Apotheker Zeitung 134, 177-189

Dingermannn, Th. (1993). Funktionelle Rezeptorexpression in Dictyostelium discoideum. Patentschrift P 43 13 933.7

Rizzuto, R., Sandoná, D., Brini, M., Marschalek, R., Dingermann, Th., and Bisson, R. (1993). Structure of the promoter region of the gene encoding cytochrome c oxidase subunit V in Dictyostelium. Eur. J. Biochem. 211, 411-414

Hofmann, J., Schumann, G., Marschalek, R., Hanenkamp, A., Bukenberger, M., Winckler, Th., and Dingermann, Th. (1993). The Dictyostelium discoideum 5S rDNA is organized in the same transcriptional orientation as the other rDNAs. Biochem. Biophys. Res. Comm. 191, 558-564

Hoja, U., Hofmann, J., Marschalek, R., and Dingermann, Th. (1993). Nucleotide sequence of a Dictyostelium discoideum gene encoding a protein homologous to the yeast ribosomal protein S31. Biochem. Biophys. Res. Comm. 190, 134-139

Marschalek, R., Hofmann, J., Schumann, G., Bach, M., and Dingermann, Th. (1993). Different organization of the retrotransposon DRE in NC4 derived strains and in other wild-type Dictyostelium discoideum strains. Eur. J. Biochem. 217, 627-631

Zündorf, I., Reinke, M, and Dingermann, Th. (1993). Expression of antibody fragments directed against Prostaglandin E2 on the surface of filamentous phage. Pharm. Pharmacol. Lett. 3, 32-35

Dingermann, Th. (1993). Kann die Molekularbiologie die Pharmazie bereichern? Arch. Pharm.326, 845

Dingermann, Th. (1993). Gentechnologie - Können wir auf sie verzichten? PTA heute 7, 652-660

Dingermann, Th. (1993). Nukleinsäuren als potentielle Pharmaka. Deutsche Apotheker Zeitung 133, 4209-4223

Rau, D., Tittelbach, H., Dingermann, Th., and Gebhart, E. (1992). Trisomy 7 in short-term cultures of colorectal adenocarcinomas Genes, Chromsomes and Cancer. 4, 104-105

Marschalek, R., Hofmann, J., Schumann, G., Gösseringer, R., and Dingermann, Th. (1992). Structure of DRE, a retrotransposable element which integrates with position-specificity upstream of Dictyostelium discoideum tRNA genes. Mol. Cell. Biol. 12, 229-239

Dingermann, Th., Frank-Stoll, U., Werner, H., Wissmann, A., Hillen, W., Jacquet, M., and Marschalek, R. (1992). RNA polymerase III catalyzed transcription can be regulated in Saccharomyces cerevisiae by the bacterial tetracycline repressor-operator system. EMBO J. 11, 1487-1492

Dingermann, Th., Werner, H., Schütz, A., Zündorf, I., Nerke, K., Knecht, D., and Marschalek, R. (1992). Establishment of a system for conditional gene expression using an inducible tRNA suppressor gene. Mol. Cell. Biol. 12, 4038-4045

Dingermann, Th., Leipold, A., Landgraf, S. Gebhart, E., Tulusan A.H. and Kersten, W. (1992). Over-expression of cellular oncogenes in cystadeno carcinomas of the ovary. Intern. J. Oncol. 1, 347-352

Rau, D., Neubauer, S., Köster, A., Giedl, J., Sachse, R., Landgraf, S., Leipold, A., Dingermann, Th., and Gebhart, E. (1992). Cytogenetic, oncogenetic and histopathologic characteristics of colorectal carcinomas with 17p abnormalities. Human Genet. 89, 64-68

Gebhart, E., Rau, D., Neubauer, S., and Dingermann, Th. (1992). Chromosome 1 in human colorectal tumors. Hum. Genet. 90, 188-190

Dingermann, Th. (1992). Vom Gewächshaus über den Fermenter in den Tierstall: Neue Wege in der Pharmazeutischen Biologie. Deutsche Apotheker Zeitung 23, 1216-122

Zündorf, I. and Dingermann, Th. (1992). Molekularbiologie: Methoden und Konzepte. Deutsche Apotheker Zeitung 26, 1373-1381

Dingermann, Th. (1992). Tumorentstehung und neue Therapiemöglichkeiten. Med. Mo. Pharm. 11, 322-332

Marschalek, R., Hofmann, J., Schumann, G., and Dingermann, Th. (1992). Two distinct subforms of the retrotransposable DRE element in NC4 strains of Dictyostelium discoideum. Nucl. Acids Res. 20, 6247-6252

Kalpaxis, D., Zündorf, I., Werner, H., Reindl, N., Boy-Marcotte, E., Jacquet, M., and Dingermann, Th. (1991). Positive selection for Dictyostelium discoideum mutants lacking UMP synthase activity based on resistance to 5-fluoroorotic acid. Mol. Gen. Genet. 225, 492-500

Köster, A., Landgraf, S., Leipold, A., Sachse, R., Gebhart, E., Tulusan, A.H., Rónay, R, Schmidt, C., and Dingermann, Th. (1991). Expression of oncogenes in human breast cancer specimens. Anticancer Res. 11, 193-202

Dingermann, Th., Troidl, E.-M., Bröker, M., and Nerke, K. (1991). Expression of human antithrombin III in the cellular slime mold Dictyostelium discoideum. Appl. Microbiol. Biotechnol. 35, 496-50

Bukenberger, M., Marschalek, R., Salzburger, W., and Dingermann, Th. (1991). Nuclear factors which bind to Dictyostelium discoideumtransfer RNA genes. Current Genetics 20, 129-135

Dingermannn, Th. (1991). Suppressor-tRNA-Genstranskriptionssysteme Patentschrift P 41 03 952.1

Hofmann, J., Schumann, G., Borschet, G., Gösseringer, R., Bach, M., Bertling, W., Marschalek, R., and Dingermann, Th. (1991). Transfer RNA genes from Dictyostelium discoideum are frequently associated with repetitive elements and contain consensus boxes in their 5'- and 3'-flanking regions. J. Mol. Biol. 222, 537-552

Rau, D., Köster, A., Tittelbach, H., Sachse, R., Landgraf, S., Neubauer, S., Giedl, J., Dingermann, Th., and Gebhart, E. (1991).Chromosome and oncogene studies in human rectal and colon carcinomas. Anticancer Res. 11, 1477-1484

Marschalek, R., and Dingermann, Th. (1991). Structure, organization and function of transfer RNA genes from the cellular slime mold Dictyostelium discoideum. In Advances in Gene Technology Vol. 2. P.J. Greenaway (ed).JAI Press Inc., Greenwich, 103-143

Marschalek, R., Kalpaxis, D., and Dingermann, Th. (1990). Temperature sensitive synthesis of transfer RNAs in vivo in Saccharomyces cerevisiae. EMBO J. 9, 1253-1258

Kalpaxis, D., Werner, H., Boy-Marcotte, E., Jacquet, M., and Dingermann, Th. (1990). Positive selection for Dictyostelium mutants lacking uridine monophosphate synthase activity based on resistance to 5-fluoro-orotic acid. Dev. Genet. 11, 396-402

Dingermann, Th., Reindl, N., Brechner, Th., Werner, H, and Nerke, K. (1990). Nonsense suppression in Dictyostelium discoideum. Dev. Genet. 11, 410-417

Marschalek, R., Borschet, G., and Dingermann, Th. (1990). Genomic organization of the transposable element Tdd-3 from Dictyostelium discoideum. Nucl. Acids Res. 18, 5751-5757

Dingermann, Th., Brechner, Th., Marschalek, R., Amon-Böhm, E., and Welker, D. (1989). tRNAGlu(GAA) genes from the cellular slime mold Dictyostelium discoideum. DNA 8, 193-204 ( Abstract )

Marschalek, R., Brechner, Th., Amon-Böhm, E., and Dingermann, Th. (1989). tRNA genes: Landmarks for integration of mobile genetic elements in Dictyostelium discoideum. Science 244, 1493-1496 ( Abstract )

Gebhart, E., and Dingermann, Th. (1989). Molecular biology of human colorectal cancer. Cancer Bull. 41, 318-324

Dingermann, Th., Reindl, N., Werner, H., Hildebrandt, M., Nellen, W., Harwood, A. Williams, J., and Nerke, K. (1989). Optimization and in situ detection of Escherichia coli ß-galactosidase gene expression in Dictyostelium discoideum. Gene 85, 353-362

Michelsen, U., Bösl, M., Dingermann, Th., and Kersten, H. (1989). The tyrT locus of Eschericha coli exhibits a regulatory function for glycine metabolism. J. Bact. 171, 5987-5994

Dingermann, Th. (1989). Structure, organization and expression of eukaryotic transfer RNA genes Mol. Gen. (Life Sci. Adv.) 8, 57-64.

Dingermann, Th., Nerke, K., Blöcker, H., and Frank, R. (1988). Structural requirements for synthesis of tRNATrp from Dictyostelium discoideum in yeast Biochimie 70, 711-719.

Von Heimendahl, G., Gebhart, E., and Dingermann, Th. (1988). Proto-oncogene activation in surgical specimens of rectal carcinoma. Anticancer Res. 8, 805-812.

Marschalek, R and Dingermann, Th. (1988). Identification of a protein factor binding to the 5'-flanking region of a tRNA gene and being involved in modulation of tRNA gene transcription in vivo in Saccharomyces cerevisiae. Nucl. Acids Res. 16, 6737-6752.

Dingermann, Th., Amon-Böhm, E., Bertling, W., Marschalek, R., and Nerke, K. (1988). The gene family of nonallelic tRNAVal(GUU) genes from the cellular slime mold Dictyostelium discoideum. Gene 73, 373-384

Bertling, W., Kaiserwerth, M., and Dingermann, Th. (1987). Comparative study of 5´-flanking sequences of eukaryotic tRNA genes: possible functional implications. Int. J. Biol. Macromol. 9, 63-70.

Dingermann, Th., Amon E., Williams, K.L., and Welker, D.L. (1987). Chromosomal mapping of tRNA genes from Dictyostelium discoideum. Mol. Gen. Gene 207, 176-187.

Dingermann, Th., and Nerke, K. (1987). Primer extension analysis of tRNA gene transcripts synthesized in vitro and in vivo Analytical Biochem. 162, 466-475.

Dingermann, Th., Nerke, K., and Marschalek, R. (1987). Influence of different 5´-flanking sequences of tRNA genes on their in vivo transcription efficiencies. Eur. J. Biochem. 170, 217-224.

Dingermann, Th., Amon-Böhm, E., Bertling, W., Marschalek, R., and Nerke, K. (1987). Structure, genomic organization and developmental expression of members of a tRNAVal(GUU) gene family of the cellular slime mold Dictyostelium discoideum. Mol. Gen. (Life Sci. Adv.) 6, 152-159.

Dingermann, Th., Bertling, W., Brechner, Th., Nerke, K., Peffley, D.M., and Sogin, M.L. (1986). Structure of two trna genes from Dictyostelium discoideum. Nucl. Acids Res. 14, 1127.

Frendewey, D., Dingermann, Th., Cooley, L. and Söll, D. (1985). Processing of precursor tRNAs in Drosophila: processing of the 3´ end involves an endonucleolytic cleavage and occures after 5´ end maturation. J. Biol. Chem. 260, 449-454.

Dingermann, Th., Bertling, W., Pistel, F. and Amon, E. (1985). Characterisation of a Dictyostelium discoideum DNA fragment coding for a putative tRNAVal (GUU) gene: evidence for a single transcription unit consisting of two overlapping class III genes. Eur. J. Biochem. 146, 449-458.

Thorbjarnardóttir, S., Uemura, H., Dingermann, Th., Rafnar, Th., Thorsteinsdóttir, S., Söll, D., and Eggertsson, G. (1985). Escherichia coli supH suppressor: temperature-sensitive missens suppression caused by an anticodon change in tRNASer(2). J. Bact. 161, 207-211.

Thorbjarnardóttir, S., Dingermann, Th., Rafnar, Th., Andersson, O.S., Söll, D., and Eggertsson, G. (1985). Leucine tRNA family of Escherichia coli: nucleotide sequence of the supP(am) suppressor gene. J. Bact. 161, 219-222.

Schaack, J., Sharp, S., Dingermann, Th., Burke, D.J., Cooley, L. and Söll, D. (1984). The extend of a eucaryotic tRNA gGene: 5´- and 3´-flanking sequence dependence for transcription and stable complex formation. J. Biol. Chem. 259, 1461-1467.

Sharp, S., Dingermann, Th., Schaack, J., DeFranco, D. and Söll, D. (1983). Transcription of eucaryotic tRNA genes in vitro: I. Analysis of control regions using a competition assay. J. Biol. Chem. 258, 2440-2446.

Schaack, J., Sharp, S., Dingermann, Th. and Söll, D. (1983). Transcription of eucaryotic tRNA genes in vitro: II. Formation of stable complexes. J. Biol. Chem. 258, 2447-2453.

Sharp, S., Dingermann, Th., Schaack, J., Scharp, J.A., Burke, D.J., DeRobertis, E.M. and Söll, D. (1983). Each element of the Drosophila tRNAArg gene split promoter directs transcription in Xenopus oocytes. Nucl. Acids Res. 11, 8677-8690.

Sharp, S., Cooley, L., DeFranco, D., Dingermann, Th. and Söll, D. (1983). Organisation and expression of tRNA genes in Drosophila melanogaster. In Recent Results in Cancer Research Vol. 84, G. Nass (ed.), Springer Verlag Berlin, pp. 1-14.

Dingermann, Th., Sharp, S., Schaack, J. and Söll, D. (1983). Stable transcription complex formation of eucaryotic tRNA genes is dependent on a limited separation of the two intragenic control regions. J. Biol. Chem. 258, 10395-10402.

Dingermann, Th., Sharp, S., Schaack, J., DeFranco, D., Johnson, D.L., Cooley, L. and Söll, D. (1982). The in vitro transcription of Drosophila tRNA genes. In: Gene Regulation, UCLA Symposia on Molecular and Cellular Biology, Vol. XXVI, Bert O´Maley and C. Fred Fox (eds.), Academic Press, New York, NY., pp. 219-234.

Dingermann, Th., Burke, B.J., Sharp, S., Schaack, J. and Söll, D. (1982). The 5´ flanking sequences of Drosophila tRNAArg genes control their in vitro transcription in a Drosophila cell extract. J. Biol. Chem. 257, 14738-14744.

DeFranco, D., Dingermann, Th., Johnson, D.L., Sharp, S. and Söll, D. (1982). Eukaryotic tRNA gene transcription is controlled by signals within and outside the mature coding sequence. In: Primary and Tertiary Structure of Nucleic Acids and Cancer Research, M.Miwa et al. (eds.), Japan Sci. Soc. Press, Tokyo, pp. 63-72.

Sharp, S., Dingermann, Th. and Söll, D. (1982). The minimum intragenic sequences required for promotion of eucaryotic tRNA gene transcription. Nucl. Acids. Res. 10, 5393-5406.

Dingermann, Th., Sharp, S., Appel, B., DeFranco, D., Mount, S., Heiermann, R., Pongs, O. and Söll, D. (1981). Transcription of cloned tRNA and 5S RNA genes in a Drosophila cell free extract. Nucl. Acids Res. 9, 3907-3918

Dingermann, Th., Ogilvie, A., Pistel, F., Mühlhofer, W. and Kersten, H. (1981). Reduced aminoacylation of asparagine-transfer RNA early in the developmental cycle of Dictyostelium discoideum: modification pattern and possible significance of the uncharged isoacceptor tRNAAsn(3). Hoppe Seyler´s Z. Physiol. Chem. 362, 763-773.

Sharp, S., DeFranco, D., Dingermann, Th., Farrel, P. and Söll, D. (1981). Internal control regions for transcription of eucaryotic tRNA genes. Proc. Natl. Acad. Sci. U.S.A. 78, 6657-6661.

Dingermann, Th., Pistel, F. and Kersten, H. (1980). Functional role of ribothymidine in transfer RNA. Eur. J. Biochem. 104, 33-40.

1977

Dingermann, Th., Schmidt, W. and Kersten, H. (1977). Modified bases in tRNA of Dictyostelium discoideum: alterations in the ribothymidine content during development. FEBS Letters 80, 205-208.