Publications

2024

  • Novischi SYP, Karoly-Lakatos A, Chok K, Bonifer C, Becker-Baldus J, Glaubitz C. Probing the allosteric NBD-TMD crosstalk in the ABC transporter MsbA by solid-state NMR. Commun Biol. 2024 Jan 5;7(1):43. doi: 10.1038/s42003-023-05617-0. PMID: 38182790; PMCID: PMC10770068.

  • Jiafei Mao, Xinsheng Jin, Man Shi, David Heidenreich, Linda J. Brown, Richard C.D. Brown, Moreno Lelli, Xiao He and Clemens Glaubitz. Mechanistic Complexity and Evolutionary Robustness of a Color Switch in Proteorhodopsins. Science Advances. 2024 10, eadj0384. accepted. doi: 10.1126/sciadv.adj0384

2023

  • Becker-Baldus J, Yeliseev A, Joseph TT, Sigurdsson ST, Zoubak L, Hines K, Iyer MR, van den Berg A, Stepnowski S, Zmuda J, Gawrisch K, Glaubitz C. Probing the Conformational Space of the Cannabinoid Receptor 2 and a Systematic Investigation of DNP-Enhanced MAS NMR Spectroscopy of Proteins in Detergent Micelles. ACS Omega. 2023 Aug 28;8(36):32963-32976. https://pubs.acs.org/doi/10.1021/acsomega.3c04681. PMID: 37720784; PMCID: PMC10500644.
  • Zhang J, Kriebel CN, Wan Z, Shi M, Glaubitz C, He X. Automated Fragmentation Quantum Mechanical Calculation of 15N and 13C Chemical Shifts in a Membrane Protein. J Chem Theory Comput. 2023 Oct 24;19(20):7405-7422. doi: 10.1021/acs.jctc.3c00621. Epub 2023 Oct 3. PMID: 37788419.
  • Weber R, Chok K, Junek S, Glaubitz C, Heckel A. Rhodamine-Sensitized Two-Photon Activation of a Red Light-Absorbing BODIPY Photocage. Chemistry. 2023 May 2;29(25):e202300149. doi: 10.1002/chem.202300149. Epub 2023 Mar 20. PMID: 36785982.

2022

  • Kriebel CN, Asido M, Kaur J, Orth J, Braun P, Becker-Baldus J, Wachtveitl J, Glaubitz C. Structural and functional consequences of the H180A mutation of the light-driven sodium pump KR2. Biophys J. 2022 Dec 16:S0006-3495(22)03933-9. doi: 10.1016/j.bpj.2022.12.023. Epub ahead of print. PMID: 36528791. Download Accepted Author Version.
  • Kriebel CN, Becker-Baldus J, Glaubitz C. Solid-state NMR spectroscopy on icrobial rhodopsins. Methods Mol Biol 2022;2501:181-206. doi: 10.1007/978-1-0716-2329-9_9. Download Preprint.
  • Mezhyrova J, Mörs K, Glaubitz C, Dötsch V, Bernhard F. Applications of Cell-Free Synthesized Membrane Protein Precipitates. Methods Mol Biol. 2022;2406:245-266. doi: 10.1007/978-1-0716-1859-2_15. PMID: 35089562.

2021

  • Bonifer C, Glaubitz C. MsbA: an ABC transporter paradigm. Biochem Soc Trans. 2021 Nov 25:BST20211030. doi: 10.1042/BST20211030. Download Accepted Author Version.
  • Dai D, Wang X, Liu Y, Yang XL, Glaubitz C, Denysenkov V, He X, Prisner T, Mao J. Room-temperature dynamic nuclear polarization enhanced NMR spectroscopy of small biological molecules in water. Nat Commun. 2021 Nov 25;12(1):6880. doi: 10.1038/s41467-021-27067-0. PMID: 34824218; PMCID: PMC8616939.
  • Asido M, Kar RK, Kriebel CN, Braun M, Glaubitz C, Schapiro I, Wachtveitl J. Transient Near-UV Absorption of the Light-Driven Sodium Pump Krokinobacter eikastus Rhodopsin 2: A Spectroscopic Marker for Retinal Configuration. J Phys Chem Lett. 2021 Jul 15;12(27):6284-6291. doi: 10.1021/acs.jpclett.1c01436. Epub 2021 Jul 2. PMID: 34213348.
  • Doroudgar M, Morstein J, Becker-Baldus J, Trauner D, Glaubitz C. How Photoswitchable Lipids Affect the Order and Dynamics of Lipid Bilayers and Embedded Proteins. J Am Chem Soc. 2021 Jun 16. doi: 10.1021/jacs.1c03524. Epub ahead of print.https://doi.org/10.1021/jacs.1c03524
  • Becker-Baldus J, Leeder A, Brown LJ, Brown RCD, Bamann C, Glaubitz C. The Desensitized Channelrhodopsin-2 Photointermediate Contains 13-cis,15-syn Retinal Schiff Base Angew Chem Int Ed Engl. 2021, epub ahead of print. doi.org/10.1002/anie.202015797
  • Pintér G, Hohmann KF, Grün JT, Wirmer-Bartoschek J, Glaubitz, C, Fürtig B, Schwalbe H. Magn Reson. 2021, 2, 291-320. doi.org/10.5194/mr-2-291-2021
  • Jakdetchai O, Eberhardt P, Asido M, Kaur J, Kriebel CN, Mao J, Leeder AJ,
    Brown LJ, Brown RCD, Becker-Baldus J, Bamann C, Wachtveitl J, Glaubitz C.
    Probing the photointermediates of light-driven sodium ion pump KR2 by DNP-
    enhanced solid-state NMR. Sci Adv. 2021 Mar 12;7(11):eabf4213. doi:
    10.1126/sciadv.abf4213
    . PMID: 33712469; PMCID: PMC7954446.
  • Li J, Shen Y, Chen Y, Zhang Z, Ma S, Wan Q, Tong Q, Glaubitz C, Liu M, Yang
    J. Structure of membrane diacylglycerol kinase in lipid bilayers. Commun Biol.
    2021 Mar 5;4(1):282. doi: 10.1038/s42003-021-01802-1. PMID: 33674677; PMCID:
    PMC7935881.

2020

  • Schulte L, Mao J, Reitz J, Sreeramulu S, Kudlinzki D, Hodirnau VV, Meier-
    Credo J, Saxena K, Buhr F, Langer JD, Blackledge M, Frangakis AS, Glaubitz C,
    Schwalbe H. Cysteine oxidation and disulfide formation in the ribosomal exit
    tunnel. Nat Commun. 2020 Nov 4;11(1):5569. doi: 10.1038/s41467-020-19372-x.
    PMID: 33149120; PMCID: PMC7642426.
  • Krug U, Gloge A, Schmidt P, Becker-Baldus J, Bernhard F, Kaiser A, Montag C,
    Gauglitz M, Vishnivetskiy SA, Gurevich VV, Beck-Sickinger AG, Glaubitz C, Huster
    D. The Conformational Equilibrium of the Neuropeptide Y2 Receptor in Bilayer
    Membranes. Angew Chem Int Ed Engl. 2020 Aug 13. doi: 10.1002/anie.202006075.
    Epub ahead of print. PMID: 32790043.
  • Kubatova N, Mao J, Eckert CE, Saxena K, Gande SL, Wachtveitl J, Glaubitz C,
    Schwalbe H. Light Dynamics of the Retinal-Disease-Relevant G90D Bovine Rhodopsin
    Mutant. Angew Chem Int Ed Engl. 2020 Jun 30;59(36):15656–64. doi:
    10.1002/anie.202003671
    . Epub ahead of print. PMID: 32602600; PMCID: PMC7496284.a
  • de Mos J, Jakob A, Becker-Baldus J, Heckel A, Glaubitz C. Light-induced uncaging for time-resolved observations of biochemical reactions by MAS NMR spectroscopy. Chemistry. 2020 Apr 2.  [Epub ahead of print] PubMed PMID: 32240561, DOI: 10.1002/chem.202000770

2019

  • Mao J, Aladin V, Jin X, Leeder AJ, Brown LJ, Brown RCD, He X, Corzilius B, Glaubitz C. Exploring Protein Structures by DNP-Enhanced Methyl Solid-State NMR Spectroscopy. J Am Chem Soc. 2019 Nov 22. [Epub ahead of print] PubMed PMID: 31756090.
  • Price DJ, Nair A, Becker-Baldus J, Glaubitz C, Kuentz M, Dressman J, Saal C. Incorporation of HPMCAS during loading of glibenclamide onto mesoporous silica improves dissolution and inhibits precipitation. Eur J Pharm Sci. 2020 Jan 1;141:105113. doi: 10.1016/j.ejps.2019.105113. Epub 2019 Oct 23. PubMed PMID: 31655207.
  •  Ditzinger F, Price DJ, Nair A, Becker-Baldus J, Glaubitz C, Dressman JB, Saal  C, Kuentz M. Opportunities for Successful Stabilization of Poor Glass-Forming Drugs: A Stability-Based Comparison of Mesoporous Silica Versus Hot Melt Extrusion Technologies. Pharmaceutics. 2019 Nov 4;11(11). pii: E577. doi:10.3390/pharmaceutics11110577. PubMed PMID: 31689980.
  • Maciejko J, Kaur J, Becker-Baldus J, Glaubitz C. Photocycle-dependent conformational changes in the proteorhodopsin cross-protomer Asp-His-Trp triad revealed by DNP-enhanced MAS-NMR. PNAS. 2019, 201817665.
  • Becker-Baldus J, Glaubitz, C. Cryo-trapped Intermediates of Retinal Proteins Studied by DNP-enhanced MAS NMR Spectroscopy. eMagRes, 2018, Vol 7: 79–92.
  • Möbius K, Kazemi S, Güntert P, Jakob A, Heckel A, Becker-Baldus J, Glaubitz C. Global response of diacylglycerol kinase towards substrate binding observed by 2D and 3D MAS NMR. Scientific Reports. 2019, 9 (1), 3995.
  • Ntountaniotis D, Andreadelis I, Kellici TF, Karageorgos V, Leonis G, Christodoulou E, Kiriakidi S, Becker-Baldus J, Stylos EK, Chatziathanasiadou MV, Chatzigiannis CM, Damalas DE, Aksoydan B, Javornik U, Valsami G, Glaubitz C, Durdagi S, Thomaidis NS, Kolocouris A, Plavec J, Tzakos AG, Liapakis G, Mavromoustakos T. Host-Guest Interactions between Candesartan and Its Prodrug Candesartan Cilexetil in Complex with 2-Hydroxypropyl-β-cyclodextrin: On the Biological Potency for Angiotensin II Antagonism. Mol Pharm. 2019 Mar 4;16(3):1255-1271. doi: 10.1021/acs.molpharmaceut.8b01212. Epub 2019 Feb 13. PubMed PMID: 30681344.
  • Asido M, Eberhardt P, Kriebel CN, Braun M, Glaubitz C, Wachtveitl J. Time-resolved IR spectroscopy reveals mechanistic details of ion transport in the sodium pump Krokinobacter eikastus rhodopsin 2. Phys Chem Chem Phys. 2019 Feb 20;21(8):4461-4471. doi: 10.1039/c8cp07418f. PubMed PMID: 30734791.

2018

  • Kaur, H; Abreu, B; Akhmetzyanov, D; Lakatos-Karoly, A; Soares, C; Prisner, T; Glaubitz, C. Unexplored nucleotide binding modes for the ABC exporter MsbA. J Am Chem Soc 2018 Oct 31;140(43):14112-14125.
  • Jawurek M, Droden J, Peter B, Glaubitz C, Hauser K. Lipid-induced dynamics of photoreceptors monitored by time-resolved step-scan FTIR spectroscopy. Chem Phys 2018, 512, 53-61
  • Tošner Z, Sarkar R, Becker-Baldus J, Glaubitz C, Wegner S, Engelke F, Glaser SJ, Reif B. Overcoming Volume Selectivity of Dipolar Recoupling in Biological Solid-State NMR Spectroscopy. Angew Chem Int Ed Engl. 2018 Jul 10.  [Epub ahead of print] PubMed PMID: 29989288.
  • Kaur J, Kriebel CN, Eberhardt P, Jakdetchai O, Leeder AJ, Weber I, Brown LJ, Brown RCD, Becker-Baldus J, Bamann C, Wachtveitl J, Glaubitz C. Solid-state NMR analysis of the sodium pump Krokinobacter rhodopsin 2 and its H30A mutant. J Struct Biol. 2018 Jun 4. pii: S1047-8477(18)30139-4. [Epub ahead of print] PubMed PMID: 29879487.
  • Joedicke L*, Mao J*°, Kuenze G*, Reinhart C, Kalavacherla T, Jonker H, Richter C, Schwalbe H, Meiler J, Preu J, Michel H° & Glaubitz C°. The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors. Nature Chem Biol 2018. published online 15.1.2018. (*) shared authorships
  • Spadaccini R, Kaur H, Becker-Baldus J, Glaubitz C. The effect of drug binding on specific sites in transmembrane helices 4 and 6 of the ABC exporter MsbA studied by DNP-enhanced solid-state NMR. Biochim Biophys Acta. 2018 Apr;1860(4):833-840. doi: 10.1016/j.bbamem.2017.10.017. Epub 2017 Oct 22. PubMed PMID: 29069570.

2017

  • Hu J, Dziumbla S, Lin J, Bibli SI, Zukunft S, de Mos J, Awwad K, Frömel T, Jungmann A, Devraj K, Cheng Z, Wang L, Fauser S, Eberhart CG, Sodhi A, Hammock BD, Liebner S, Müller OJ, Glaubitz C, Hammes HP, Popp R, Fleming I. Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy. Nature. 2017 Dec 6.
  • Leeder AJ, Brown LJ, Becker-Baldus J, Mehler M, Glaubitz C, Brown RCD. Synthesis of Isotopically Labelled All-Trans Retinals for DNP-Enhanced Solid State NMR Studies of Retinylidene Proteins. J Labelled Comp Radiopharm. 2017 Oct  28.
  • Mehler M, Eckert CE, Leeder AJ, Kaur J, Fischer T, Kubatova N, Brown LJ, Brown RCD, Becker-Baldus J, Wachtveitl J, Glaubitz C. Chromophore Distortions in Photointermediates of Proteorhodopsin visualized by DNP-enhanced solid-state NMR. J Am Chem Soc. 2017 Oct 13.
  • Köhler T, Weber I, Glaubitz C, Wachtveitl J. Proteorhodopsin Photocycle Kinetics Between pH 5 and pH 9. Photochem Photobiol. 2017 May;93(3):762-771.
  • Eckert CE, Kaur J, Glaubitz C, Wachtveitl J. Ultrafast Photoinduced Deactivation Dynamics of Proteorhodopsin. J Phys Chem Lett. 2017 Jan 19;8(2):512-517.

2016

  • Kaur H, Lakatos-Karoly A, Vogel R, Nöll A, Tampé R, Glaubitz C. Coupled ATPase-adenylate kinase activity in ABC transporters. Nature Commun. 2016 Dec 22;7:13864.
  • Lehnert E*, Mao J*, Mehdipour AR, Hummer G, Abele R, Glaubitz C°, Tampé R°. Antigenic Peptide Recognition on the Human ABC Transporter TAP Resolved by DNP-Enhanced Solid-State NMR Spectroscopy.J Am Chem Soc. 2016: 138(42), 13967-13974, (*) shared authorships
  • Jawurek, M, Glaubitz C, Hauser, K. Impact pf the lipid environment on the protonation dynamics of bacteriorhodopsin studied with time-resolved step-scan FTIR spectroscopy. Biomed Spect Imag 2016 5(2), 167-174.

2015

  • Mehler M, Eckert CE, Busche A, Kulhei J, Michaelis J, Becker-Baldus J, Wachtveitl J, Dötsch V, Glaubitz C. Assembling a Correctly Folded and Functional Heptahelical Membrane Protein by Protein Trans-splicing. J Biol Chem. 2015 Nov 13;290(46):27712-22.
  • Hellmich UA, Mönkemeyer L, Velamakanni S, van Veen HW, Glaubitz C. Effects of nucleotide binding to LmrA: A combined MAS-NMR and solution NMR study. Biochim Biophys Acta. 2015 Dec;1848(12):3158-65. doi: 10.1016/j.bbamem.2015.10.003.
  • Becker-Baldus J, Bamann C, Saxena K, Gustmann H, Brown LJ, Brown RC, Reiter C, Bamberg E, Wachtveitl J, Schwalbe H, Glaubitz C. Enlightening the photoactive site of channelrhodopsin-2 by DNP-enhanced solid-state NMR spectroscopy. Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):9896-901.
  • Maciejko J, Mehler M, Kaur J, Lieblein T, Morgner N, Ouari O, Tordo P, Becker-Baldus J, Glaubitz C. Visualizing Specific Cross-Protomer Interactions in the Homo-Oligomeric Membrane Protein Proteorhodopsin by Dynamic-Nuclear-Polarization-Enhanced Solid-State NMR. J Am Chem Soc. 2015 Jul 22;137(28):9032-43.
  • Bühl E, Braun M, Lakatos A, Glaubitz C, Wachtveitl J. Fluorescence and excited state dynamics of the deprotonated Schiff base retinal in proteorhodopsin. Biol Chem. 2015 Sep;396(9-10):1109-15.
  • Kaur H, Lakatos A, Spadaccini R, Vogel R, Hoffmann C, Becker-Baldus J, Ouari O, Tordo P, Mchaourab H, Glaubitz C. The ABC exporter MsbA probed by solid state NMR – challenges and opportunities. Biol Chem. 2015 Sep;396(9-10):1135-49.
  • Kellici TF, Ntountaniotis D, Leonis G, Chatziathanasiadou M, Chatzikonstantinou AV, Becker-Baldus J, Glaubitz C, Tzakos AG, Viras K, Chatzigeorgiou P, Tzimas S, Kefala E, Valsami G, Archontaki H, Papadopoulos MG, Mavromoustakos T. Investigation of the interactions of silibinin with 2-hydroxypropyl-β-cyclodextrin through biophysical techniques and computational methods. Mol Pharm. 2015 Mar 2;12(3):954-65.

2014

  • Mao J, Do NN, Scholz F, Reggie L, Mehler M, Lakatos A, Ong YS, Ullrich SJ, Brown LJ, Brown RC, Becker-Baldus J, Wachtveitl J, Glaubitz C. Structural basis of the green-blue color switching in proteorhodopsin as determined by NMR spectroscopy. J Am Chem Soc. 2014 Dec 17;136(50):17578-90.
  • Jakdetchai O, Denysenkov V, Becker-Baldus J, Dutagaci B, Prisner TF, Glaubitz C. Dynamic nuclear polarization-enhanced NMR on aligned lipid bilayers at ambient temperature. J Am Chem Soc. 2014 Nov 5;136(44):15533-6.
  • Ntountaniotis D, Kellici T, Tzakos A, Kolokotroni P, Tselios T, Becker-Baldus  J, Glaubitz C, Lin S, Makriyannis A, Mavromoustakos T. The application of solid-state NMR spectroscopy to study candesartan cilexetil (TCV-116) membrane interactions. Comparative study with the AT1R antagonist drug olmesartan. Biochim Biophys Acta. 2014 Oct;1838(10):2439-50.
  • Dutagaci B, Becker-Baldus J, Faraldo-Gomez J, Glaubitz, C. Ceramide - Lipid Interactions studied by MD Simulations and Solid-State NMR. Biochim Biophys Acta. 2014; 1838(10): 2511-9.
  • Bamann C, Bamberg E, Wachtveitl J, Glaubitz C. Proteorhodopsin. Biochim Biophys Acta. 2014 May;1837(5):614-625.
  • Ullrich SJ, Hölper S, Glaubitz C. Paramagnetic doping of a 7TM membrane protein in lipid bilayers by Gd³⁺-complexes for solid-state NMR spectroscopy. J Biomol NMR. 2014 Jan;58(1):27-35.
  • Chen Y, Zhang Z, Tang X, Li J, Glaubitz C, Yang J. Conformation and Topology of Diacylglycerol Kinase in E.coli Membranes Revealed by Solid-state NMR Spectroscopy. Angew Chem Int Ed Engl. 2014 Apr 2.
  • Becker-Baldus J, Glaubitz, C. Symmetrically Asymmetric: EmrE Seen from the NMR Perspective. In: Membrane Transport Mechanism. Springer 2014, Ed. Ziegler/Krämer.

2013

  •  Mao J, Akhmetzyanov D, Ouari O, Denysenkov V, Corzilius B, Plackmeyer J, Tordo P, Prisner TF, Glaubitz C. Host-guest complexes as water-soluble high-performance DNP polarizing agents. J Am Chem Soc. 2013 Dec 26;135(51):19275-81.
  • Ong YS, Lakatos A, Becker-Baldus J, Pos KM, Glaubitz C. Detecting substrates bound to the secondary multidrug efflux pump EmrE by DNP-enhanced solid-state NMR. J Am Chem Soc. 2013 Oct 23;135(42):15754-62.
  • Mehler M, Scholz F, Ullrich SJ, Mao J, Braun M, Brown LJ, Brown RC, Fiedler SA, Becker-Baldus J, Wachtveitl J, Glaubitz C. The EF loop in green proteorhodopsin affects conformation and photocycle dynamics. Biophys J. 2013 Jul 16;105(2):385-97.
  • Ullrich SJ, Glaubitz C. Perspectives in enzymology of membrane proteins by solid-state NMR. Acc Chem Res. 2013 Sep 17;46(9):2164-71.
  • Janke C, Scholz F, Becker-Baldus J, Glaubitz C, Wood PG, Bamberg E, Wachtveitl J, Bamann C. Photocycle and vectorial proton transfer in a rhodopsin from the eukaryote Oxyrrhis marina. Biochemistry. 2013 Apr 23;52(16):2750-63.
  • Mörs K, Roos C, Scholz F, Wachtveitl J, Dötsch V, Bernhard F, Glaubitz C. Modified lipid and protein dynamics in nanodiscs. Biochim Biophys Acta. 2013 Apr;1828(4):1222-9.
  • Stehle J, Scholz F, Löhr F, Reckel S, Roos C, Blum M, Braun M, Glaubitz C, Dötsch V, Wachtveitl J, Schwalbe H. Characterization of the ground state dynamics of proteorhodopsin by NMR and optical spectroscopies. J Biomol NMR. 2012 Dec;54(4):401-13.
  • Mörs K, Hellmich UA, Basting D, Marchand P, Wurm JP, Haase W, Glaubitz C. A lipid-dependent link between activity and oligomerization state of the M. tuberculosis SMR protein TBsmr. Biochim Biophys Acta. 2013 Feb;1828(2):561-7.

2012

  • Herz J, Verhoefen MK, Weber I, Bamann C, Glaubitz C, Wachtveitl J. Critical role of Asp227 in the photocycle of proteorhodopsin. Biochemistry. 2012 Jul 17;51(28):5589-600.
  • Lakatos, A., Mörs, K., Glaubitz, C. (2011) How to investigate interactions between membrane proteins and ligands by solid-state NMR. Meth. Mol. Biol. 2012;914:65-86.
  • Hellmich UA, Lyubenova S, Kaltenborn E, Doshi R, van Veen HW, Prisner TF, Glaubitz C. Probing the ATP hydrolysis cycle of the ABC multidrug transporter LmrA by pulsed EPR spectroscopy. J Am Chem Soc. 2012 Apr 4;134(13):5857-62.
  • Reckel S, Lopez JJ, Löhr F, Glaubitz C, Dötsch V. In-cell solid-state NMR as a tool to study proteins in large complexes. Chembiochem. 2012 Mar 5;13(4):534-7.

2011

  • Reggie, L., Lopez, J.J., Collinson, I., Glaubitz, C., Lorch, M. (2011) Dynamic Nuclear Polarization-Enhanced Solid-State NMR of a (13)C-Labeled Signal Peptide Bound to Lipid-Reconstituted Sec Translocon. J Am Chem Soc, 133(47) 19084-6
  • Hellmich, U.A., Duchardt-Ferner, E., Glaubitz, C., Wöhnert, J. (2011) Backbone NMR resonance assignments of the nucleotide binding domain of the ABC multidrug transporter LmrA from Lactococcus lactis in its ADP-bound state.Biomol NMR Assign, in press
  • Reckel, S., Gottstein, D., Stehle, J., Löhr, F., Verhoefen, M.K., Takeda, M., Silvers, R., Kainosho, M., Glaubitz, C., Wachtveitl, J., Bernhard, F., Schwalbe, H., Güntert, P., Dötsch, V. (2011) Solution NMR structure of Proteorhodopsin. Angew Chem Int Ed  50, 1-6
  • Hüsch, J., Dutagaci, B., Glaubitz, C., Geppert, T., Schneider, G., Harms, M., Müller-Goymann, C.C., Fink, L., Schmidt, M.U., Setzer, C., Zirkel, J., Rebmann, H., Schubert-Zsilavecz, M., Abdel-Tawab, M. (2011) Structural properties of co-called NSAID-phospholipid-complexes. Eur. J. Pharm. Sci. 44, 103-116
  • Verhoefen, M.K, Schaefer, G., Shastri, S., Weber, I., Glaubitz, C., Maentele, W., Wachtveitl, J. (2011) Low temperature FTIR spectroscopy provides new insights in the pH-dependent proton pathway of proteorhodopsin.Biochim Biophys Acta 1807, 1583-90
  • Taylor, G.F., Wood, S.P., Moers, K., Glaubitz, C., Werner, J., Williamson, P.T.F (2011) Morphologiacal Differences between ß2-Microglobulin in Fibrils and Inclusion Bodies. ChemBioChem 12, 556-558
  • Hempelmann, F., Hölper, S., Verhoefen, M.K., Wörner, A., Köhler, T., Fiedler, S.A., Pfleger, N., Wachtveitl., S., Glaubitz. C. (2011) The His75-Asp97 Cluster in Green Proteorhodopsin. J. Am. Chem. Soc.133, 4645-54
  • Yang, J., Aslimovska, L., Glaubitz, C. (2011) Molecular Dynamics of Green Proteorhodopsin in Lipid Bilayers by Solid-state NMR., J. Am. Chem. Soc. 133, 4874-4881
  • Ullrich, S.J., Hellmich, U.A., Ullrich, S., Glaubitz, C. (2011) Interfacial enzyme kinetics of a membrane bound kinase analyzed by real-time MAS -NMR. Nature Chem. Biol. 7, 263-270
  • Zutz, A., Hoffmann, J., Hellmich, U.A., Glaubitz, C., Ludwig, B., Brutschy, B., Tampe, R. (2011) Asymmetric ATP Hydrolysis Cycle of the Heterodimeric Multidrug ABC Transport Complex TmrAB from Thermus thermophilus. J. Biol. Chem. 286, 7104-7115
  • Hefke F, Bagaria A, Reckel S, Ullrich SJ, Dötsch V, Glaubitz C, Güntert P. (2011) Optimization of amino acid type-specific (13)C and (15)N labeling for the backbone assignment of membrane proteins by solution- and solid-state NMR with the UPLABEL algorithm. J. Biomol. NMR 49, 75-84

2010

  • Maslennikov, I, Klammt, C., Hwang, E., Kefala, G., Okamura, M., Esquivies, L., Mörs, K., Glaubitz, C., Kwiatkowski, W., Jeon, Y.H., Choe, S. (2010) Membrane domain structures of three classes of histidine kinase receptros by cell-free expression and rapid NMR analysis.Proc.Natl.Acad.Sci.U.S.A. 107, 10902-10907
  • Hoffmann, J., Aslimovska, L., Bamann, C., Glaubitz, C., Bamberg, E., Brutschy, B.(2010) Studying the stoichiometries of membrane proteins by mass spectrometry: microbial rhodopsins and a potassium ion channel.Phys.Chem.Chem.Phys. 12, 3480-5
  • Cherepanov, A. V., Glaubitz, C., Schwalbe, H. (2010) High resolution studies of uniformly C-13, N15- labelled RNA by solid-state NMR spectroscopy.Angewandte Chemie Int. Ed. 49, 4747-4750
  • Kumar, J., Sreeramulu, S., Schmidt, T.L., Richter, C., Vonck, J., Heckel, A., Glaubitz, C., Schwalbe, H. (2010) Prion Protein Amyloid Formation Involves Structural Rearrangements in the C-Terminal Domain, ChemBioChem 11, 1208-1213
  • Hoffmann, M., Lopez, J.J., Pergola, C., Feisst, C., Pawelczik, S., Jakobsson, P.J., Sorg, B.L., Glaubitz, C., Steinhilber, D., Werz, O. (2010) Hyperforin induces Ca2+-independent arachidonic acid release in human 2 platelets by facilitating cytosolic phospholipase A2 activation through select 3 phosphilipid interactions, BBA Biomembranes 1801, 462-72.

2009

  • Lopez, J.J., Kaiser, C., Asami, S., Glaubitz, C. (2009) Higher sensitivity through selective 13C excitation in solid-state NMR spectroscopy. J.Am.Chem.Soc. 131, 15970-15971
  • Lörinczi, E., Verhoefen, M.K., Wachtveitl., J., Woerner, A.C., Glaubitz, C., Engelhard, M., Bamberg, E., Friedrich, T. (2009) Voltage- and pH-Dependet Changes in Vectoriality of Photocurrents Mediated by Wild-type and Mutant Proteorhodopsins upon Expression in Xenopus Oocytes, J.Mol. Biol. 393, 320-341
  • Maier, T.J. Schiffmann, S., Birod, K., Angioni.C., Hoffmann, M., Lopez, J.J., Glaubitz, C., Steinhilber, D., Geisslinger, G., Grösch, S. (2009) Cellular membranes function as a storage compartments for celecoxib, J. Mol. Med. 87, 981-993
  • Rinnenthal, J., Richter, C., Nozinovic., S., Fürtig, B., Lopez, J.J., Glaubitz, C., Schwalbe, H.. (2009) RNA phosphodiester backbone dynamics of a perdeuterated cUUCg tetraloop RNA from phosphorous-31 NMR relaxation analysis, J. Biomol. NMR 45, 143-155
  • Hellmich, U.A., Glaubitz, C. (2009) NMR and EPR Studies of Membrane Transporters, Biol. Chem.390, 815-834
  • Pfleger, N., Woerner, A.C., Yang, J., Shastri, S., Hellmich, .A., Aslimovska, L., Maier, M.S.M., Glaubitz, C. (2009) Solid-state NMR and functional studies on proteorhodopsin, BBA Bioenergetics, 1787, 697-705
  • Hellmich, U.A., Pfleger, N., Glaubitz, C. (2009) 19F-MAS NMR on Proteorhodopsin: Enhanced protocol for site-specific labeling for general application to membrane proteins, Photochem Photobiol. 85, 535-539
  • Schäfer, G., Shastri, S., Verhoefen, M.K., Vogel, V., Glaubitz, C., Wachtveitl, J., Mäntele, W. (2009) Characterizing the structure and photocycle of PR 2D crystals with CD-and FTIR spectroscopy, Photochem Photobiol. 85, 529-534
  • Verhoefen, M.K., Neumann, K., Weber, I., Glaubitz C., Wachtveitl, J. (2009) Primary reaction dynamics of proteorhodopsin mutant D97N observed by femtossecond infrared and visible spectroscopy, Photochem. Photobiol. 85, 540-549

2008

  • Göbel, M.W., Dürner, G., Lopez, J.L., Breitung, S.T., Suhartono, M., Glaubitz, C. (2008) A practical Synthesis of the 13C/15N-labelled Tripeptide N-Formyl-Met-Leu-Phe, useful as a Reference in Solid-State NMR  Spectroscopy, Beilstein J.Org Chem, 4,35
  • Hellmich, U.A., Haase, W., Velamakanni, S., van Veen, H., Glaubitz, C., (2008) Caught in the Act: ATP hydrolysis of an ABC-Multidrug transporter followed by real-time Magic Angle Spinning NMR, Febs Letters 582, 3557-62
  • Gieldon, A., Lopez. J.J., Glaubitz, C., Schwalbe, H. (2008) Theoretical Study of the Human Bradykinin - Bradykinin B2 Receptor Complex Supported by Solid-State NMR Spectrocopy Data, ChemBioChem 9, 2487-2497
  • Neumann, K., Verhoefen, M.K., Weber, I., Glaubitz, C., Wachtveitl, J. (2008) Initial reaction dynamics of proteorhodopsin observed by femtosecond infrared and visible spectroscopy, Biophys. J. 94, 4796-4897
  • Lopez, J.J., Kaiser*, C., Shastri, S., Glaubitz, C. (2008) Double quantum filtering homonuclear MAS NMR correlation spectra: A tool for membrane protein studies, J. Biomol. NMR 41, 97-104
  • Lehner, I., Basting, D., Meyer, B., Haase, W., Manolikas, T., Kaiser, C., Karas, M., Glaubitz C. (2008) The key residue for substrate transpor in the EmrE dimer is asymmetric, J. Biol. Chem, 283, 3281-3288
  • Lopez., J.J., Shukla, A.K., Reinhart, C., Schwalbe, H., Michel, H., Glaubitz, C. (2008) The structure of bradykinin bound to the human GPCR bradykini-2 as determined by solid-state NMR, Angew., Chem. Int. Ed. 47, 1668-1671
  • Klyszejnko*, A.L., Shastri*, S., Mari. S.A., Grubmüller, H., Müller, D.J., Glaubitz, C. (2008) Folding and Assembly of Proteorhodopsin, JMB 376, 35-41
  • Pfleger, N. Lorch, M., Wörner, A, Shastri, S., Glaubitz, C. (2008) Characterisation of Schiff base and Chromophore in Green Proteorhodopsin by Solid-State NMR, J. Biomol. NMR 40, 15-21
  • Basting, D., Lorch*, M., Lehner, I., GLaubitz, C. (2008) Transport Cycle Intermediate in Small Multidrug Resistance Protein is revealed by Substrate Fluorescence, FASEB J 22, 365-373

2007

  • Kaiser, C., Lopez, J.J., Bermel, W., Glaubitz, C. (2007) Dual Transormation of Homonuclear Solid-State NMR Spectra - an Option to Decrease Measuring Time, BBA Biomem. 1768, 3107-3115
  • Shastri, S., Vonck, J. Haase, W., Pfleger, N., Kuehlbrandt, W., Glaubitz, C. (2007) Proteorhodopsin: Characterisation of 2D Crystals by Electron Microscopy and Solid-State NMR, BBA Biomemm 1768, 3012-3019
  • Diller, A., Roy, E., Gast, P., van Gorkum, H.J., Glaubitz, C., Jeschke, G. Matysik, J., Alia, A. (2007) 15N photochemically induced dynamic nuclear polarization magic-angle spinning NMR analysis of the electron donor of photosystem II, PNAS 104, 12767-12771
  • Siarheyeva, A., Lopez, J.J., Lehner, I., Hellmich, U.A., van Veen, H., Glaubitz, C. (2007) Probing the Molecular Dynamics of the ABC Multidrug Transpporter LmrA by Deuterium Solid-State NMR, Biochemistry 46, 3075-83
  • Werner, K., Lehner, I., Dhiman, H.K., Richter, C., Glaubitz, C., Schwalbe, H., Klein-Seetharaman, J., Khorana, G. (2007) Combined solid state ans solution NMR sutdies of alpha, epsilon-N-15 labeled bovine rhodopsin, J. Biomol. NMR 37, 303-312
  • Lenz, M., Woerner, A., Glaubitz, C., Wachtveitl, J., (2007) Photoisomerization in Proteorhodopsin mutant D97N, Photochem Photobiol 83, 226-231
  • Lopez, J.J., Mason, A.J., Kaiser, C., Glaubitz, C. (2007) Separated Local Field NMR Experiments on riented Samples Rotating at the Magic Angle, J. Biomol. NMR 37, 97-111

2006

  • Siarheyeva, A., Lopez, J.J., Glaubitz, C. (2006) Localization of multidrug transporter substrates within model membranes, Biochemistry 45, 6203-11
  • Basting, D., Lehner, I., Lorch, M. and Glaubitz, C. (2006) Investigating transport proteins by solid state NMR, Naunyn-Schmiedberg´s Arch Pharmacol 372, 451-464

2005

  • Mason, A.J., Martinez, A., Glaubitz, C., Danos, O., Kichler, A. and Bechinger, B. (2005) The antibiotic and DNA-transfecting peptide LAH4 selectively associates with, and disorders, anionic lipids in mixed membranes, FASEB J 19, 320-322
  • Lorch, M., Fahem, S., Kaiser, C., Weber, I., Mason, A.J., Bowie, J., Glaubitz, C. (2005) How to prepare membrane proteins for solid-state NMR - A case study on the alpha-helical membrane protein DGK from E.coli, ChemBioChem 6, 1693-1700
  • Lorch, M., Lehner, I., Siarheyeva, A., Basting D., Pfleger, N., Manolikas, T., Glaubitz, C. (2005) NMR and fluorescence spectroscopy approaches to seconndary - and primary active multidrug efflux pumps, BioChemSocTrans 33, 873-877
  • Mason, A.J., Lopez, J.J., Beyermann, M., Glaubitz, C. (2005) A spectroscopic Study of the Membrane Interaction of Tuberoinfundibular Peptide of 39 Residues (TIP39), BBA Biomembranes 1714, 1-10
  • Diller, A., Alia, Roy, E., Gast, P., van Gorkum, H.J.M., Zaanem, J., de Groot, HJM, Glaubitz, C., Matysik, J. (2005) Photo-CIDNP solid-state NMR on photosystems I and II: What makes P680 special ?, Photosynthesis Research 84, 303-308
  • Mason, A.J., Turner, G., Glaubitz, C. (2005) Conformational Heterogeneity of transmembrane residues after the Schiff base reprotonation of bacteriorhodopsin - N-15 CPMAS NMR of D85N/T170C membranes,FEBS J 272, 2152-2164

before 2005

  • Mason, A.J., Siarheyeva, A., Haase, W., Lorch, M., van Veen, H. Glaubitz, C. (2004) Amino acid type selctive isotpe labelling of the multidrug ABC transporter LmrA for solid-state NMR studies, FEBS Lett 568, 117-121
  • Mason, A.J., Grage, S.L., Straus, S.K., Glaubitz, C., Watts, A. (2004) Identifying anisotropic constraints in multiply labeled bacteriorhodopsin by N-15 MAOSS NMR: A general apporach to structural studies of membrane proteins, Biophys. J. 86, 1610-1617
  • Klammt, C., Lohr, F., Schäfer, B., Haase, W., Dötsch, V., Rüterjans, H., Glaubitz, C. Bernhard, F. (2004) High level cell-free expression and specific labeling of integral membrane proteins, Eur. J. Biochem. 271, 568-580
  • Spooner, P.J.R., Sharples, J.M., Verhoeven, M.A., Lugtenburg, J., Glaubitz, C., Watts, A. (2002) Relative orientation between the beta-ionone ring and the polyene chain for the chromophore of rhodopsin in native membranes, Biochemistry 41, 7549-7555
  • Glaubitz, C., Carravetta, M., Eden, M., Levitt, M. (2001) Toward recoupling in marcoscopically ordered samples of membrane proteins, Persp. on Solid State NMR (ef. Kiihne, de Groot), 71-81
  • Middleton, D.A., Ahmed, Z., Glaubitz, C., Watts, A. (2000) REDOR NMR on a hysdrophobic peptide in oriented membranes, J Magn Reson 147, 366-370
  • Gaubitz, C., Groger, A., Gottschalk, K., Spooner, P., Watts, A., Schuldiner, S., Kessler, H. (2000) P-31-CP-MAS NMR studies on TPP+ bound to the ion-coupled multidrug transport protein EmrE, Febs Lett 480, 127-131
  • Grobner, G., Burnett, I.J., Glaubitz, C., Choi, G., Mason, A.J., Watts, A. (2000) Observations of light induced structural changes of retinal within rhodopsin, Nature 405, 810-813
  • Glaubitz, C. (2000) An introduction to MAS NMR spectroscopy on oirented membrane proteins, Conceps in Magnetic Resonance 12, 137-151
  • Glaubitz, C., Grobner, G., Watts, A. (2000) Structural and orientational information of teh membrane embedded M13 coat protein by C-13-MAS NMR spectroscopy, BBA Biomembranes 1463, 151-161
  • Grobner, G., Glaubitz, C., Watts, A. (1999) Probing membrane surfaces and the location of membrane-embedded peptides by C-13 MAS NMR using lanthanide ions, J. Magn Reson 141, 335-339
  • Watts, A., Burnett, I.J., Glaubitz, C., Grobner, G., Middleton, D.A., Spooner, P.J.R., Watts, J.A., Williamson, P.T.F. (1999) Membrane protein stucture determination by solid state NMR, Nat. Prod. Rep. 16, 419-423
  • Glaubitz, C., Burnett, I.J., Grobner, G., Mason, A.J., Watts, A. (1999) Deuterium-MAS NMR spectroscopy on oriented membrane proteins: Applications to photointermediates of bacteriorhodopsin, J Am Chem Soc 121, 5787-5794
  • Areas, J.A.G., Grobner, G., Glaubitz, C., Watts, A. (1998) Interaction of a type II myosin with biological membranes studied by H-2 solid state NMR, Biochemistry 37, 5582-5588
  • Glaubitz, C., Watts, A. (1998) Magic angle-oriented sample spinning (MAOSS): A new approach toward biomembrane studies, J Magn Reson 130, 305-316
  • Grobner, G., Choi, G., Burnett, I.J., Glaubitz, C., Verdegem, P.J.E., Lugtenburg, J., Watts, A. (1998) Photoreceptor rhodopsin: structural and conformational study of its chromophore 11-cis retinal in oriented membranes by deuterium solid state NMR, FEBS LETT 422, 201-204
  • Areas, J.A.G., Grobner, G.J., Pellacani, L.B., Glaubitz, C., Watts, A. (1997) Use of solid-state H-2 NMR for studying protein-lipid interactions at emulsion interfaces, Magn Reson Chem 35, 119-124
  • Grobner, G., Taylor, A., Williamson, P.T.F., Choi. G., Glaubitz, C., Watts, J.A., deGrip, W.J., Watts, A. (1997) Macroscopic orientation of natural and model membranes for structural studies, Anal Biochem 254, 132-138