Publications

Metrics and Publication records in databases:

h-index (Web of Science): 10
Number of published articles (PubMed): 41
ResearcherID H-3178-2011 Link
ORCID: Link
ResearchGate: Link

Original articles

  1. Exploring the druggability of conserved RNA regulatory elements in the SARS-CoV-2 genome.
    Sreeramulu S, Richter C, Berg H, Wirtz Martin MA, Ceylan B, Matzel T, Adam J, Altincekic N, Azzaoui K, Bains JK, Blommers MJJ, Ferner J, Fürtig B, Göbel M, Grün JT, Hengesbach M, Hohmann KF, Hymon D, Knezic B, Martins J, Mertinkus KR, Niesteruk A, Peter SA, Pyper DJ, Qureshi NS, Scheffer U, Schlundt A, Schnieders R, Stirnal E, Sudakov A, Tröster A, Vögele J, Wacker A, Weigand JE, Wirmer-Bartoschek J, Wöhnert J, Schwalbe H.
    Angew Chem Int Ed Engl. 2021 Jun 23.
    doi: 10.1002/anie.202103693. Online ahead of print.
  2. Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications
    Altincekic N*, Korn SM*, Qureshi NS*, Dujardin M*, Ninot-Pedrosa M*, Abele R, Abi Saad MJ, Alfano C, Almeida FCL, Alshamleh I, de Amorim GC, Anderson TK, Anobom CD, Anorma C, Bains JK, Bax A, Blackledge M, Blechar J, Bockmann A#, Brigandat L, Bula A, Butikofer M, Camacho-Zarco AR, Carlomagno T, Caruso IP, Ceylan B, Chaikuad A, Chu F, Cole L, Crosby MG, de Jesus V, Dhamotharan K, Felli IC, Ferner J, Fleischmann Y, Fogeron ML, Fourkiotis NK, Fuks C, Furtig B, Gallo A, Gande SL, Gerez JA, Ghosh D, Gomes-Neto F, Gorbatyuk O, Guseva S, Hacker C, Hafner S, Hao B, Hargittay B, Henzler-Wildman K, Hoch JC, Hohmann KF, Hutchison MT, Jaudzems K, Jovic K, Kaderli J, Kalnins G, Kanepe I, Kirchdoerfer RN, Kirkpatrick J, Knapp S, Krishnathas R, Kutz F, Zur Lage S, Lambertz R, Lang A, Laurents D, Lecoq L, Linhard V, Lohr F, Malki A, Bessa LM, Martin RW, Matzel T, Maurin D, McNutt SW, Mebus-Antunes NC, Meier BH, Meiser N, Mompean M, Monaca E, Montserret R, Marino Perez L, Moser C, Muhle-Goll C, Neves-Martins TC, Ni X, Norton-Baker B, Pierattelli R, Pontoriero L, Pustovalova Y, Ohlenschlager O, Orts J, Da Poian AT, Pyper DJ, Richter C, Riek R, Rienstra CM, Robertson A, Pinheiro AS, Sabbatella R, Salvi N, Saxena K, Schulte L, Schiavina M, Schwalbe H#, Silber M, Almeida MDS, Sprague-Piercy MA, Spyroulias GA, Sreeramulu S, Tants JN, Tars K, Torres F, Tows S, Trevino MA, Trucks S, Tsika AC, Varga K, Wang Y, Weber ME, Weigand JE, Wiedemann C, Wirmer-Bartoschek J, Wirtz Martin MA, Zehnder J, Hengesbach M# and Schlundt A#
    Front Mol Biosci, 2021, 8, 653148.
    doi: 10.3389/fmolb.2021.653148
  3. Eukaryote specific RNA and protein features facilitate assembly and catalysis of H/ACA snoRNPs
    Trucks S
    *, Hanspach G* and Hengesbach M#
    Nucleic Acids Res, 2021, 49, 4629-4642.
    doi: 10.1093/nar/gkab177
  4. The protective role of m1A during stress-induced granulation
    Alriquet M, Calloni G, Martinez-Limon A, Delli Ponti R, Hanspach G, Hengesbach M, Tartaglia GG and Vabulas RM
    J Mol Cell Biol, 2021, 12, 870-880.
    doi: 10.1093/jmcb/mjaa023
  5. Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy
    Wacker A*, Weigand JE*, Akabayov SR, Altincekic N, Bains JK, Banijamali E, Binas O, Castillo-Martinez J, Cetiner E, Ceylan B, Chiu LY, Davila-Calderon J, Dhamotharan K, Duchardt-Ferner E, Ferner J, Frydman L, Furtig B, Gallego J, Grun JT, Hacker C, Haddad C, Hahnke M, Hengesbach M, Hiller F, Hohmann KF, Hymon D, de Jesus V, Jonker H, Keller H, Knezic B, Landgraf T, Lohr F, Luo L, Mertinkus KR, Muhs C, Novakovic M, Oxenfarth A, Palomino-Schatzlein M, Petzold K, Peter SA, Pyper DJ, Qureshi NS, Riad M, Richter C, Saxena K, Schamber T, Scherf T, Schlagnitweit J, Schlundt A, Schnieders R, Schwalbe H, Simba-Lahuasi A, Sreeramulu S, Stirnal E, Sudakov A, Tants JN, Tolbert BS, Vogele J, Weiss L, Wirmer-Bartoschek J, Wirtz Martin MA, Wohnert J and Zetzsche H
    Nucleic Acids Res, 2020, 48, 12415-12435.
    doi: 10.1093/nar/gkaa1013
  6. Structural dynamics govern substrate recruitment and catalytic turnover in H/ACA RNP pseudouridylation Schmidt A*, Hanspach G* and Hengesbach M#
    RNA Biol, 2020, 1-10.
    doi: 10.1080/15476286.2020.1842984
  7. RNA secondary structure dependence in METTL3-METTL14 mRNA methylation is modulated by the N-terminal domain of METTL3
    Meiser N
    *, Mench N and Hengesbach M#
    Biol Chem, 2020, 402, 89-98.
    doi: 10.1515/hsz-2020-0265
  8. Site-Specific Detection of Arginine Methylation in Highly Repetitive Protein Motifs of Low Sequence Complexity by NMR
    Altincekic N*, Lohr F, Meier-Credo J, Langer JD, Hengesbach M, Richter C and Schwalbe H#
    J Am Chem Soc, 2020, 142, 7647-7654.
    doi: 10.1021/jacs.0c02308
  9. Genetic Code Expansion Facilitates Position-Selective Labeling of RNA for Biophysical Studies
    A. Hegelein*, D. Müller*, S. Größl, M. Göbel, M. Hengesbach, H. Schwalbe#
    Chemistry – A European Journal, 26 (8), 1800-1810 (Highlighted with Journal Cover)
    doi: 10.1002/chem.201904623
  10. Assembly of Proteins by Free RNA during the Early Phase of Proteostasis Stress
    M. Alriquet M., A. Martínez-Limón, G. Hanspach, M. Hengesbach, G. G Tartaglia, G. Calloni, R.M. Vabulas
    J Proteome Res. 2019;18(7):2835–2847.
    doi:10.1021/acs.jproteome.9b00143
  11. Combined smFRET and NMR analysis of riboswitch structural dynamics
    Bains JK*, J. Blechar*, V. de Jesus*, N. Meiser*, H. Zetzsche, B. Fürtig#, H. Schwalbe#, and M. Hengesbach#
    Methods, 2019 Jan 15;153:22-34.
    doi: 10.1016/j.ymeth.2018.10.004
  12. The Protein Microenvironment Governs the Suitability of Labeling Sites for Single-Molecule Spectroscopy of RNP Complexes.
    Schmidt A
    , N. Altincekic, H. Gustmann, J. Wachtveitl and M. Hengesbach#
    ACS Chem Biol, 2018 13(9): 2472-2483
  13. NMR Structural Profiling of Transcriptional Intermediates Reveals Riboswitch Regulation by Metastable RNA Conformations
    Helmling, A. Wacker, M.T. Wolfinger, I.L. Hofacker, M. Hengesbach, B. Fürtig, and H. Schwalbe#
    JACS, 2017 Feb. 139(7):2647-2656
  14. Ligand-modulated folding of the full-length adenine riboswitch probed by NMR and single-molecule FRET spectroscopy
    S. Warhaut, K.R. Mertinkus, P. Höllthaler, B. Fürtig,M. Heilemann, M. Hengesbach, and H. Schwalbe#
    Nucleic Acids Res. 2017 Feb 15.
    doi: 10.1093/nar/gkx110
  15. Rapid NMR screening of RNA secondary structure and binding
    Helmling, S. Keyhani, F. Sochor, B. Fürtig, M. Hengesbach, and H. Schwalbe#
    Journal of Biomolecular NMR 2015 Sep;63(1):67-76.
  16. Differential scanning fluorimetry for monitoring RNA stability
    Silvers, H. Keller, H. Schwalbe#, M. Hengesbach#
    ChemBioChem 2015 May 4;16(7):1109-14 (Highlighted as Inside Cover)
  17. Single molecule FRET reveals a rugged folding energy landscape for the human telomerase RNA pseudoknot domain
    Hengesbach, N.-K. Kim, J. Feigon, and M.D. Stone
    Angewandte Chemie International Edition, 2012 Jun 11;51(24):5876-9.
  18. Single-molecule FRET reveals a cooperative effect of two methyl group modifications in the folding of human mitochondrial tRNALys
    Yu. Kobitski, M. Hengesbach, S. Seidu-Larry, K. Dammertz, C. S. Chow, A. van Aerschot, G.U. Nienhaus and M. Helm
    Chemistry & Biology, 2011 Jul 29;18(7):928-36
  19. Single-molecule FRET studies of counterion effects on the free energy landscape of human mitochondrial
    lysine tRNA
    Dammertz, M. Hengesbach, M. Helm, G.U. Nienhaus, and A. Yu.Kobitski
    Biochemistry, 2011 Apr 19;50(15):3107-15
  20. 4. Formation of a stalled early intermediate of Pseudouridine synthesis monitored by real-time FRET
    Hengesbach, F. Voigts-Hoffmann, B. Hofmann and M. Helm
    RNA, 2010 Mar;16(3):610-20.
    Sculpting an RNA conformational energy landscape by a methyl group modification
    - a single-molecule FRET study
    Yu. Kobitski, M. Hengesbach, M. Helm, and G.U. Nienhaus
    Angewandte Chemie International Edition, 2008. 47(23): p. 4326-30
    (Arbeit in deutscher Sprache: Angewandte Chemie, 2008. 120(23): p. 4398-4402)
  21. Use of DNAzymes for site-specific analysis of ribonucleotide modifications
    Hengesbach*, M. Meusburger*, F. Lyko and M. Helm
    RNA, 2008 Jan. 14(1): p. 180-7
  22. A Methyl Group Controls Conformational Equilibrium in Human Mitochondrial tRNALys
    Voigts-Hoffmann, M. Hengesbach, A. Yu. Kobitski, A. van Aerschot, P. Herdewijn, G.U. Nienhaus, and M. Helm
    JACS, 2007 Nov. 129(44): p. 13382-3

Reviews & Methods

  1. From Antisense RNA to RNA Modification: Therapeutic Potential of RNA-Based Technologies
    Adachi H, Hengesbach M, Yu YT and Morais P
    Biomedicines, 2021, 9
    doi: 10.3390/biomedicines9050550M.
  2. NMR Spectroscopy of Large Functional RNAs: From Sample Preparation to Low-Gamma Detection
    Schnieders R, Knezic B, Zetzsche H, Sudakov A, Matzel T, Richter C, Hengesbach M, Schwalbe H and Furtig B
    Curr Protoc Nucleic Acid Chem, 2020, 82, e116.
    doi: 10.1002/cpnc.116
  3. Genetic Code Expansion Facilitates Position-Selective Modification of Nucleic Acids and Proteins
    Muller D, Trucks S, Schwalbe H and Hengesbach M#
    Chempluschem, 2020, 85, 1233-1243.
    doi: 10.1002/cplu.202000150
  4. Cooperative Analysis of Structural Dynamics in RNA-Protein Complexes by Single-Molecule Forster Resonance Energy Transfer Spectroscopy
    Meiser N, Fuks C and Hengesbach M
    Molecules, 2020, 25,
    doi: 10.3390/molecules25092057
  5. Strategic labelling approaches for RNA single-molecule spectroscopy
    Hanspach G, Trucks S, Hengesbach M. #
    RNA Biology. 2019 Mar 15:1-14.
    doi: 10.1080/15476286.2019.1593093.
  6. Single-molecule Analysis of Telomerase Structure and Function
    M. Hengesbach, B.M. Akiyama, and M.D. Stone
    Current Opinion in Chemical Biology, 2011 Dec;15(6):845-52.
  7. A post-labeling Approach for the Characterization and Quantification of RNA modifications Based on Site-directed Cleavage by DNAzymes
    M. Meusburger*, M. Hengesbach*, and M. Helm
    Methods in Molecular Biology: DNA and RNA editing, 2011, 718; p259-70
  8. RNA Intramolecular Dynamics by Single-Molecule FRET
    M. Hengesbach, A. Kobitski, F. Voigts-Hoffmann, C. Frauer, G.U. Nienhaus, and M. Helm
    Current Protocols in Nucleic Acid Chemistry, Sep 2008, Chapter 11; Unit 11.12
  9. Exploring the folding free energy landscape of small RNA molecules by single-pair Förster resonance energy transfer
    A. Yu. Kobitski, A.  Nierth, M. Hengesbach, A.  Jäschke, M. Helm, and G.Ulrich Nienhaus
    Biophysical Reviews and Letters, 2008. 3(4): p. 439-457.

NMR assignment publications

  1. (1)H, (13)C, (15)N and (31)P chemical shift assignment for stem-loop 4 from the 5'-UTR of SARS-CoV-2
    Vogele J, Ferner JP, Altincekic N, Bains JK, Ceylan B, Furtig B, Grun JT, Hengesbach M, Hohmann KF, Hymon D, Knezic B, Lohr F, Peter SA, Pyper D, Qureshi NS, Richter C, Schlundt A, Schwalbe H, Stirnal E, Sudakov A, Wacker A, Weigand JE, Wirmer-Bartoschek J, Wohnert J and Duchardt-Ferner E
    Biomol NMR Assign, 2021,
    doi: 10.1007/s12104-021-10026-7
  2. (1)H, (13)C and (15)N chemical shift assignment of the stem-loop 5a from the 5'-UTR of SARS-CoV-2
    Schnieders R, Peter SA, Banijamali E, Riad M, Altincekic N, Bains JK, Ceylan B, Furtig B, Grun JT, Hengesbach M, Hohmann KF, Hymon D, Knezic B, Oxenfarth A, Petzold K, Qureshi NS, Richter C, Schlagnitweit J, Schlundt A, Schwalbe H, Stirnal E, Sudakov A, Vogele J, Wacker A, Weigand JE, Wirmer-Bartoschek J and Wohnert J
    Biomol NMR Assign, 2021, 15, 203-211.
    doi: 10.1007/s12104-021-10007-w
  3. (1)H, (13)C and (15)N backbone chemical shift assignments of SARS-CoV-2 nsp3a
    Salvi N, Bessa LM, Guseva S, Camacho-Zarco A, Maurin D, Perez LM, Malki A, Hengesbach M, Korn SM, Schlundt A, Schwalbe H and Blackledge M
    Biomol NMR Assign, 2021, 15, 173-176.
    doi: 10.1007/s12104-020-10001-8
  4. (1)H, (13)C, and (15)N backbone chemical shift assignments of the C-terminal dimerization domain of SARS-CoV-2 nucleocapsid protein
    Korn SM, Lambertz R, Furtig B, Hengesbach M, Lohr F, Richter C, Schwalbe H, Weigand JE, Wohnert J and Schlundt A
    Biomol NMR Assign, 2021, 15, 129-135.
    doi: 10.1007/s12104-020-09995-y
  5. (1)H, (13)C, and (15)N backbone chemical shift assignments of coronavirus-2 non-structural protein Nsp10
    Kubatova N, Qureshi NS, Altincekic N, Abele R, Bains JK, Ceylan B, Ferner J, Fuks C, Hargittay B, Hutchison MT, de Jesus V, Kutz F, Wirtz Martin MA, Meiser N, Linhard V, Pyper DJ, Trucks S, Furtig B, Hengesbach M#, Lohr F, Richter C, Saxena K, Schlundt A, Schwalbe H#, Sreeramulu S, Wacker A, Weigand JE, Wirmer-Bartoschek J and Wohnert J
    Biomol NMR Assign, 2021, 15, 65-71.
    doi: 10.1007/s12104-020-09984-1
  6. (1)H, (13)C, and (15)N backbone chemical shift assignments of the apo and the ADP-ribose bound forms of the macrodomain of SARS-CoV-2 non-structural protein 3b
    Cantini F, Banci L, Altincekic N, Bains JK, Dhamotharan K, Fuks C, Furtig B, Gande SL, Hargittay B, Hengesbach M, Hutchison MT, Korn SM, Kubatova N, Kutz F, Linhard V, Lohr F, Meiser N, Pyper DJ, Qureshi NS, Richter C, Saxena K, Schlundt A, Schwalbe H, Sreeramulu S, Tants JN, Wacker A, Weigand JE, Wohnert J, Tsika AC, Fourkiotis NK and Spyroulias GA
    Biomol NMR Assign, 2020, 14, 339-346.
    doi: 10.1007/s12104-020-09973-4
  7. (1)H, (13)C, and (15)N backbone chemical shift assignments of the nucleic acid-binding domain of SARS-CoV-2 non-structural protein 3e
    Korn SM, Dhamotharan K, Furtig B, Hengesbach M, Lohr F, Qureshi NS, Richter C, Saxena K, Schwalbe H, Tants JN, Weigand JE, Wohnert J and Schlundt A
    Biomol NMR Assign, 2020, 14, 329-333.
    doi: 10.1007/s12104-020-09971-6

Book Chapters

  1. Handbook of RNA Biochemistry, 2nd edition, 2014
    Editors: Roland K. Hartmann, Albrecht Bindereif, Astrid Schön, Eric Westhof
    Chapter „RNA Ligation“, J.J. Turunen, L.V. Pavlova, M. Hengesbach, M. Helm, S. Müller, R.K. Hartmann, and M.J. Frilander

Commentaries

  1. The how & why of looking at individual RNAs
    Hengesbach M. #
    RNA Biol. 2019;16(9):1075–1076.
  2. Structural basis for regulation of ribosomal RNA 2'-O-methylation
    M. Hengesbach, H. Schwalbe#
    Angewandte Chemie International Edition, 2014 Feb 10;53(7):1742-4
    (Article in German: Angewandte Chemie, 2014. 126(7): p. 1770-1772)

  

Editorial activities & Outreach

  1. Einzelmolekül-FRET-Spektroskopie
    Trendberichte, Nachrichten aus der Chemie August 2021
  2. Gemeinschaftlich in Krisenzeiten: NMR-Strukturbiologie gegen COVID-19.
    Schlundt A, Wirtz MA, Knezic B, Hengesbach M, Fürtig B, Weigand JE, Wöhnert J, Ferner J, Saxena K, Wacker A, Richter C, Sreeramulu S, Wirmer-Bartoschek J, Schwalbe H; Im Namen von Mehr als 50 Wissenschaftlerinnen und Wissenschaftlern in Frankfurt und Darmstadt.
    Biospektrum (Heidelb). 2020;26(4):440-441.
    doi: 10.1007/s12268-020-1396-0
  3. Single molecule techniques – Special focus issue in RNA Biology 04/2019
    Editor: M. Hengesbach

            

 *: Joint authorship

#: Corresponding authorship