Navigationshilfe

Hauptnavigation

Seiteninhalt

titelleiste_lang

MelanieHB

Melanie Weber

Doctoral student

Research project

Active hearing in the bushcricket Mecopoda elongata

The tympanal hearing organs of insects emit distortion-product otoacoustic emissions (DPOAEs) whose characteristics are similar to those measured in vertebrates. In vertebrates such emissions provide evidence of nonlinearities in the cochlear mechanics and of active sound amplification. In contrast to vertebrates, the exact cellular origin of DPOAEs in insects is still unknown.

In my doctoral thesis I use the ear of the bushcricket Mecopoda elongata as an experimental model to answer the following questions: Do the sensory cells of the tympanal organ (or its accessory structures) act as active force amplifiers? And do such activities generate the DPOAEs? To detect the cellular elements (such as tubulin, myosin, prestin) which may potentially be involved in DPOAE generation, I apply immunohistochemical, histological, and biomolecular techniques.

In collaboration with Doreen Moeckel, we test whether the DPOAEs depend on intrinsic properties of the tympanal sensilla. Hence we evoke and record DPOAEs while manipulating the sensory cells of the tympanal organ mechanically or with pharmacological substances

meco_bein
Fig 1 (a) Adult female of the tropical bushcricket M. elongata raised in our laboratory. The auditory organ is situated in the tibia of each foreleg (arrow). (b) The sensory neurons (sn) are linearly arranged next to the tympanum (tym) while the cap cells (cc) are arranged above the auditory trachea.

Support by a stipend from the Jürgen Manchot Foundation.

Further readings

Weber M (2004): Untersuchungen über neuroaktive Substanzen in tympanalen Hörorganen der Laubheuschrecke Mecopoda elongata. Diplomarbeit, Fachbereich Biologie und Informatik, J.W. Goethe-Universität, Frankfurt a. M. pp81.

Publications

2009, 2008, 2006, 2005

 

 

geändert am 02. März 2012  E-Mail: Webmaster AK NBabendroth@bio.uni-frankfurt.de

|

| Zur Navigationshilfe
empty

Seitenabschlussleiste


Druckversion: 02. März 2012, 16:19
http://www.uni-frankfurt.de/fb/fb15/institute/inst-2-zellb-neuro/AK-Koessl/Group_members/m_weber/index.html