Publikationen Prof. Jörg Stehle

Original- und Übersichtsarbeiten | Artikel und Bücher

2011 - 2019

Jilg A, Bechstein P, Saade A, Dick M, Li TX, Tosini G, Rami A, Zemmar A, Stehle JH (2019) Melatonin modulates daytime-dependent synaptic plasticity and learning efficiency. J Pineal Res, 66: e12553

Cordani L, Tagliazucchi E, Vetter C, Hassemer C, Roenneberg T, Stehle JH, Kell CA (2018) Endogenous modulation of human visual cortex activity improves perception at twilight. Nat Commun, 9: 1274

Rawashdeh O, Jilg A, Maronde E, Fahrenkrug J, Stehle JH (2016) Period1 gates the circadian modulation of memory-relevant signaling in mouse hippocampus by regulating the nuclear shuttling of the CREB kinase pP90RSK. J Neurochem, 138: 731-745

Stehle JH, Rawashdeh O (2016) Ribosomal RNA - a tail wagging the dog? J Neurochem, 136: 673-676

Serchov T, Jilg A, Wolf CT, Radtke I, Stehle JH, Heumann R (2016) Ras Activity Oscillates in the Mouse Suprachiasmatic Nucleus and Modulates Circadian Clock Dynamics. Mol Neurobiol, 53: 1843-1855

Rawashdeh O, Jilg A, Jedlicka P, Slawska J, Thomas L, Saade A, Schwarzacher SW, Stehle JH (2014) PERIOD1 coordinates hippocampal rhythms and memory processing with daytime. Hippocampus, 24:712-723

Wunderer F, Kühne S, Jilg A, Ackermann K, Sebesteny T, Maronde E, Stehle JH (2013) Clock gene expression in the human pituitary gland. Endocrinology, 154: 2046-2057

Maronde E, Saade A, Ackermann K, Goubran-Botros H, Pagan C, Bux R, Bourgeron T, Dehghani F, Stehle JH (2011) Dynamics in enzymatic protein complexes offer a novel principle for the regulation of melatonin synthesis in the human pineal gland. J Pineal Res. 51:145-155

Stehle JH, Saade A, Rawashdeh O, Ackermann K, Jilg A, Sebestény T, Maronde E (2011) A survey of molecular details in the human pineal gland in the light of phylogeny, structure, function and chronobiological diseases. J Pineal Res, 51:17-43

2006 - 2010

Jilg A, Lesny S, Peruzki N, Schwegler H, Selbach O, Dehghani F, Stehle JH (2010) Temporal dynamics of mouse hippocampal clock gene expression support memory processing. Hippocampus 20: 377-388

Rawashdeh O, Stehle JH (2010) Ageing or NOT, clock genes are important for memory processes: an interesting hypothesis raising many questions. Aging, 2: 259-260

Rami A, Bechmann I, Stehle JH (2008) Exploiting endogenous anti-apoptotic proteins for novel therapeutic strategies in cerebral ischemia. Prog Neurobiol, 85: 273-296

Ackermann K, Dehghani F, Bux R, Kauert G, Stehle JH (2007) Day-night expression patterns of clock genes in the human pineal gland. J Pineal Res 43: 185-94

Maronde E, Pfeffer M, Glass Y, Stehle JH (2007) Transcription factor dynamics in pineal gland and liver of the Syrian hamster (Mesocricetus auratus) adapts to prevailing photoperiod. J Pineal Res 43: 16-24

Ackermann K, Bux R, Rub U, Korf HW, Kauert G, Stehle JH (2006) Characterization of human melatonin synthesis using autoptic pineal tissue. Endocrinology 147: 3235-3242

Ackermann K, Stehle JH. (2006) Melatonin synthesis in the human pineal gland: advantages, implications, and difficulties. Chronobiol Int 23:369-379

2000 - 2005

Karolczak M, Korf HW, Stehle JH (2005) The rhythm and blues of gene expression in the rodent pineal gland. Endocrine 27: 89-100

Jilg A, Moek J, Weaver DR, Korf HW, Stehle JH, von Gall C (2005) Rhythms in clock proteins in the mouse pars tuberalis depend on MT1 melatonin receptor signalling. Eur J Neurosc, 22: 2845-2854

Kell CA, Stehle JH (2005) Just the two of us: melatonin and adenosine in rodent pituitary function. Ann Med, 37: 105-120

Von Gall C, Weaver DR, Moek J, Jilg A, Stehle JH, Korf HW (2005) Melatonin plays a crucial role in the regulation of rhythmic clock gene expression in the mouse pars tuberalis. Ann N Y Acad Sci, 1040: 508-511

Kell CA, Dehghani F, Wicht H, Molina CA, Korf HW, Stehle JH (2004) Distribution of transcription factor inducible cyclicAMP early repressor (ICER) in rodent brain and pituitary. J Comp Neurol 478: 379-394

Karolczak M, Burbach GJ, Sties G, Korf HW, Stehle JH (2004) Clock gene mRNA and protein rhythms in the pineal gland of mice. Eur J Neurosci. 2004 19: 3382-8

Jin X, von Gall C, Pieschl RL, Gribkoff VK, Stehle JH, Reppert SM, Weaver DR (2003) Targeted disruption of the mouse Mel1b Melatonin receptor. Mol Cell Biol 23: 1054-1060

Stehle JH, von Gall C, Korf HW (2003) Melatonin – a clock output, a clock-input. J Neuroendocrinol 15:383-389

HW Korf, C. v. Gall, JH Stehle (2003) The circadian system and melatonin: lessons from rats and mice. Chronobiol Int 20:697-710

Von Gall C, Garabette ML, Frenzel S, Kell CA, Dehghani F, Schumm-Draeger PM, Weaver DR, Korf HW, Hastings MH & Stehle JH (2002). Rhythmic gene expression in mouse pituitary depends on heterologous sensitisation by the neurohormone melatonin. Nature Neuroscience 5: 234-238

Stehle JH, von Gall C, Korf HW (2002) Organisation of the circadian system in melatonin-proficient C3H and melatonin-deficient C57BL mice: a comparative investigation. Cell Tissue Res 309: 73-182

von Gall C, Stehle JH, Weaver DR (2002) Mammalian melatonin receptors: molecular biology and signal transduction Cell Tissue Res 309: 151-162

Von Gall C, Schneider-Hüther I, Pfeffer M, Dehghani F, Korf HW & Stehle JH (2001) Clock gene protein mPER1 is rhythmically synthesised and under cAMP control in the mouse pineal gland. J Neuroendocrinol 13: 313-316

Stehle JH, Gall C & Korf HW (2001) Analysis of cell signalling in the rodent pineal gland deciphers regulators of dynamic transcription in neuro-/endocrine cells. Eur J Neurosci 14:1-9

Stehle JH, von Gall C, Schomerus C & Korf HW (2001) Of rodents and ungulates and melatonin: creating a uniform code for darkness by different signalling mechanisms. J Biol Rhythms 16:312-325

von Gall C, Lewy A, Schomerus C, Vivien-Roels B, Pevét P, Korf HW & Stehle JH (2000) Transcription factor dynamics and neuroendocrine signalling in the mouse pineal gland: a comparative analysis between melatonin 'knockdown' C57BL mice and melatonin-proficient C3H mice. Eur J Neurosci 12: 964-972

von Gall, Weaver DR, Kock M, Korf HW & Stehle JH (2000) Melatonin limits transcriptional impact of phosphoCREB in the mouse SCN via the Mel1a receptor. Neuroreport 11: 1803-1807

Staiger JF, Bisler S, Schleicher A, Gass P, Stehle JH & Zilles K (2000) Exploration of a novel environment leads to the expression of inducible transcription factors in barrel-related columns. Neuroscience 99: 7-16

1992 - 1999

Maronde E, Pfeffer M, Olcese J, Molina CM, Schlotter F, Dehghani F, Korf HW & Stehle JH (1999) Transcription factors in neuroendocrine regulation: rhythmic changes in phosphoCREB and ICER levels frame melatonin synthesis J Neurosci19:3326-3336

Pfeffer M, Maronde M, Molina CA, Korf HW & Stehle JH (1999) Inducibility of ICER protein in rat pinealocytes: a highly sensitive natural reporter for regulated gene transcription. Mol Pharmacol 56: 279-289

Pfeffer M, Kühn R, Krug L, Korf HW & Stehle JH (1998) Rhythmic variation in b1-adrenergic receptor mRNA levels in rat pineal gland: circadian and developmental regulation. Eur J Neurosci 10: 2896-2904

von Gall C, Duffield G, Kopp M, Hastings M, Korf H-W & Stehle JH (1998) CREB in the mouse SCN: a molecular integrator coding the phase adjusting stimuli of light, glutamate, PACAP and melatonin for clockwork access. J Neurosci 18: 10389-10397

Stehle JH & Korf HW (1996) Neuroendokrine Signaltransduktion: das Pinealorgan als Modell für cAMP-modulierte Genexpression. Neuroforum 4/96:13-22

Stehle JH, Foulkes N, Pévet P & Sassone-Corsi P (1995) Developmental maturation of pineal gland function: synchronized CREM inducibility and adrenergic stimulation. Mol Endocrinol 9: 706-716

Stehle JH (1995) Pineal gene expression: dawn in a dark matter. J Pineal Res 19:179-190

Weaver D, Stehle JH, Stopa E & Reppert S (1993) Melatonin receptors in human and monkey hypothalamus and pituitary: implications for circadian and reproductive responses to melatonin. J Clin Endocr Metab 76: 295-301

Stehle JH, Foulkes N, Molina C, Simonneaux V, Pévet P & Sassone-Corsi P (1993) Adrenergic signals direct rhythmic expression of a transcriptional repressor CREM in the pineal gland. Nature 365: 314-320

Stehle JH, Rivkees S, Lee J, Weaver D, Deeds J & Reppert S (1992) Molecular cloning of the cDNA for an A2-like adenosine receptor. Mol Endocrinol 6: 384-393

Artikel und Bücher


Korf HW, Schomerus C & Stehle JH (1998) The Pineal Organ, its Hormone Melatonin, and the Photoneuroendocrine System. Advances in Anatomy, Embryology, and Cell Biology, Springer, Berlin, New York, Vol 146, pp. 1-100