The Glaubitz Lab: Membrane Protein Research by NMR

Welcome to the Glaubitz Lab!
The Glaubitz Lab resolves the molecular mechanisms of membrane proteins. Current research focuses on 7TM receptors, novel microbial retinal proteins (KR2, PR ChR-2), ABC transporters and membrane-bound kinases. In addition, we study the effect of lipid-protein interactions and the influence of small molecules on membrane order, dynamics and polymorphism. Our methodological approach is centered around solid-state NMR, which enables working directly with proteoliposomes, and is complemented by many additional biochemical and biophysical techniques. Our work involves both high-field MAS-NMR (up to 850 MHz) as well as dynamic nuclear polarization, a novel hybrid method combining the advantages from both NMR and EPR spectroscopy, which pushes sensitivity by orders of magnitude. This website provides an introduction to our research, lists recent publications, informs about teaching activities and announces work opportunities for those interested in joining the lab. We are part of the Institute for Biophysical Chemistry, the Centre for Biomolecular Magnetic Resonance (BMRZ) and the Cluster of Excellence Macromolecular Complexes (CEF).
Joining the lab
Publications & Theses

Publications & Theses
Latest publications and PhD theses:
- New paper in ACS Omega: DNP-enhanced MAS NMR on the CB2 Receptor
- New paper in Biophysical Journal: Ion selectivity of the KR2 light-driven sodium pump
- New paper in JACS: The effect of photoswitchable lipids on membranes and proteins
- New paper in Angewandte Chemie: Retinal on the Channelrhodopsin-2 desenitized state
- New paper in Science Advances: DNP-NMR on KR2 photointermediates
- New paper in Nature Commun: DNP-NMR on nascent chain ribosome complexes
Group Members
Group Members
Teaching

Teaching
Biophysical Chemistry/Structural Biology/General Spectroscopy/NMR Spectroscopy
Equipment
