Group members

Group Head

 

Univ.-Prof. Dr. Stefan Knapp

Raum: N140-020

Tel.: 069/798-29871
E-Mail: knapp[at]pharmchem.uni-frankfurt.de

Prof Stefan Knapp studied Chemistry at the University of Marburg (Germany) and at the University of Illinois (USA). He did his PhD in protein crystallography at the Karolinska Institute in Stockholm (Sweden) (1996) and continued his career at the Karolinska Institute as a postdoctoral scientist (1996-1999). In 1999, he joined the Pharmacia Corporation as a principal research scientist in structural biology and biophysics. He left the company in 2004 to set up a research group at the Structural Genomics Consortium at Oxford University (SGC). From 2008 to 2015 he was a Professor of Structural Biology at the Nuffield Department of Clinical Medicine (NDM) at Oxford University (UK) and between 2012 and 2015 he was the Director for Chemical Biology at the Target Discovery Institute (TDI). He joined Frankfurt University (Germany) in 2015 as a Professor of Pharmaceutical Chemistry and the Buchmann Institute of Molecular Life Sciences. Since 2017 he is the CSO of the newly founded SGC node at the Goethe-University Frankfurt.

Sekretariat


 

Martina Scholz

Raum: N250/3.05

Tel.: 069/798-29303
E-Mail: scholz[at]iap.uni-frankfurt.de

Bio 1

Dr. Krishna Saxena
Group leader

Raum: BMLS 3.654

Tel.: 069/798-42510
E-mail: saxena[at]em.uni-frankfurt.de

Frederic Farges
PhD student

Raum:

Tel.: 069/798-
E-Mail: farges[at]pharmchem.uni-frankfurt.de

Christopher Lenz
PhD student

Raum: 2.638 Buchmann Inst.

Tel.: 069/798-42510
E-Mail: lenz[at]pharmchem.uni-frankfurt.de

Dr. Christian Munoz Sosa
Research assistant

BMLS 2.638a

Tel.: 069/798-42708
Email: munozsosa[at]pharmchem.uni-frankfurt.de

Martin Schwalm
PhD student

Raum: BMLS 3.671

Tel.: 069/798-42701
E-mail: Schwalm[at]pharmchem.uni-frankfurt.de

Bio 2

 

Dr. Andreas Joerger
Group leader

Raum: N240/303a

Tel.: 069/798-29875
E-Mail: Joerger[at]pharmchem.uni-frankfurt.de

Dimitrios Ilias Balourdas
PhD student

Raum: N100/2.11

Tel.: 069/798-29307
E-mail: balourdas[at]pharmchem.uni-frankfurt.de

Crystallography

Dr. Andreas Krämer
Group leader

Raum: N240/303a

Tel.: 069/798-29875
E-Mail: kraemer[at]pharmchem.uni-frankfurt.de

Yeojin Kim

Raum N100-211

Tel.: 269/798-29307
E-Mail: kim[at]pharmchem.uni-frankfurt.de

Dr. Adarsh Kumar

Raum N100/2.11

Tel.: 069/798-29307
Email: Kumar[at]pharmchem.uni-frankfurt.de

Dr. Xiaomin Ni

Raum N240/3.03b

Tel.: 269/798-29401
E-Mail: ni[at]em.uni-frankfurt.de

Rezart Zhubi
Technician

Raum: N100/ 2.11

Tel.: 069/798-29307
E-Mail: zhubi[at]pharmchem.uni-frankfurt.de

Medchem (Kinases)

Dr. Thomas Hanke
Group leader

Raum: N250/210

Tel.: 069/798-29313
E-Mail: Hanke[at]pharmchem.uni-frankfurt.de

Jennifer Amrhein
PhD student

Raum: N250/2.07

Tel.: 069/798-29874
E-Mail: Amrhein[at]pharmchem.uni-frankfurt.de


 

Joshua Gerninghaus
PhD student

Raum N250/2.10

Francesco Aleksy Greco
PhD student

Raum N250/2.10

Tel.: 069/798-29313
E-Mail: greco[at]pharmchem.uni-frankfurt.de

Theresa Mensing
PhD student

Raum: N250/2.07

Tel.: 069/798-29874
E-mail: mensing[at]pharmchem.uni-frankfurt.de

Nicolai Raig
PhD student

Raum: N250/ 2.07

Tel.: 069/798-29874
E-Mail:raig[at]pharmchem.uni-frankfurt.de

Marcel Rak
PhD student

Raum N260/2.09

Tel.: 069/798-29317
E-Mail: rak[at]pharmchem.uni-frankfurt.de

 

E3s and PROTACs

Dr. Vaclav Nemec
Group leader

Raum: N240/2.03

Tel.: 069/798-29914
Email: nemec[at]pharmchem.uni-frankfurt.de

Nicolas Bauer
PhD student

Raum N240 2.10

Tel.: 069/798-29496
E-Mail: bauer[at]pharmchem.uni-frankfurt.de


 

Dr. Jelena Bozilovic

Raum: N240/2.07

Tel.: 069/798-29800
E-Mail: bozilovic[at]chemie.uni-frankfurt.de


 

Dr. Anton Ruben Hamann
Postdoc

Raum: N250-207

Tel.: 069/798-xxxxx
E-Mail: hamann[at]pharmchem.uni-frankfurt.de

Lasse Hoffmann
PhD student

Raum: N 260-207

Tel.: 069/798-29800
E-Mail: La.Hoffmann[at]pharmchem.uni-frankfurt.de

Nebojsa Miletic
PhD student

Raum N240/2.10

Tel.: 069/798-29496
E-mail: miletic[at]pharmchem.uni-frankfurt.de


 

Nikos To
Technician

Raum:

Tel.: 069/798-
E-Mail: To[at]pharmchem.uni-frankfurt.de

Janik Weckesser
PhD student

Raum: N260/ 2.09

Tel.: 069/798-29317
E-Mail: weckesser[at]pharmchem.uni-frankfurt.de

Management

  Ralf Braden
Technician

Raum: N260/2.05

Tel.: 069/798-29315
E-Mail: Braden[at]pharmchem.uni-frankfurt.de

Dr. Sandra Häberle

BMLS 3.655

Tel.:
Email: Haeberle[at]pharmchem.uni-frankfurt.de

Dr. Natalie Schneider

Raum: BMLS 3.651

Tel.: 069/798-42707
E-Mail: natalie.schneider[at]bio.uni-frankfurt.de

Maria Trallero
European Affairs and Financial Coordinator

Raum: BMLS 3.655

Tel.: 069/798-42507
E-mail: maria.trallero[at]pharmchem.uni-frankfurt.de

Dr. Claudia Tredup
Scientific Coordinator

Raum N240/303b

Tel.: 069/798-29401
Email: tredup[at]pharmchem.uni-frankfurt.de

Haotian Wang
Senior Laboratory Coordinator

Raum: BMLS 3.639

Tel.: 069/798-42524
E-Mail: H.Wang[at]em.uni-frankfurt.de
Lilia Weizel
Technician

Raum: N260/2.07

Tel.: 069/798-29800
E-Mail: Weizel[at]pharmchem.uni-frankfurt.de

Molecular Tools to Explore Cellular Networks

The group creates a diverse range of cellular model systems to establish the efficacy of novel inhibitors and PROTACs on their cognate target protein and characterize the effects of the compounds on cellular health. We further explore the biological function of the targeted proteins as well as validate their role in different disease models as target for pharmacological intervention.

Dr. Susanne Müller-Knapp
Group Leader

Raum: BMLS 3.637

Tel.: 069/798-42714
E-Mail: susanne.mueller-knapp(at)bmls.de

Dr. Benedict-Tilman Berger
Team leader

Raum: BMLS 3.672

Tel.: 069/798-42422
E-Mail: b.berger[at]chemie.uni-frankfurt.de 

Lena Berger
PhD student

Raum BMLS 3.672

Tel.: 069/798-42422
E-Mail: kilian[at]pharmchem.uni-frankfurt.de


 

Lewis Elson
Technician

Raum: BMLS 3.631

Tel.: 069/798-42706
E-Mail: Elson[at]pharmchem.uni-frankfurt.de

Amelie Tjaden
PhD student

Raum BMLS 3.672

Tel.: 069/798-42422
E-mail: tjaden[at]pharmchem.uni-frankfurt.de

Autophagy

Dr. Vladimir Rogov
Group Leader

Raum: BMLS 3.657

Tel.: 069/798-
E-mail: rogov[at]pharmchem.uni-frankfurt.de

 

Viktoria Morasch
Technician

Raum: BMLS 3.672

Tel.: 069/798-42422
E-Mail: morasch[at]pharmchem.uni-frankfurt.de

Pseudokinases and Baculo Expression

Neurodegeneration is a burning issue of our aging population, but there are no reliable cures. We work on better understanding the Parkinson's disease risk factors LRRK2 and RAB10 (also on related kinases and GTPases) to identify prospects for therapeutic intervention. With the focus on enzymatic assays and structural biology, we explore different modalities to targeting these proteins (reversible and covalent inhibitors, PROTACs).

Dr. Sebastian Mathea
Group Leader

Raum: BMLS 3.639

Tel.: 069/798-42707
E-Mail: mathea[at]pharmchem.uni-frankfurt.de

Kamal Rayees Abdul Azeez
PhD student

Raum: 2.638 Buchmann Inst.

Tel.: 069/798-42510
E-Mail: abdulazeez[at]pharmchem.uni-frankfurt.de

Dr. Deep Chatterjee

Raum: N100/2.11

Tel.: 069/798-29307
E-Mail: chatterjee[at]nmr.uni-frankfurt.de

Dr. Verena Dederer

Raum: BMLS 3.670

Tel.: 069/798-
Email: dederer[at]pharmchem.uni-frankfurt.de

Covalent Inhibitors

Dr. Sandra Röhm
Group Leader

Raum: N260/2.09

Tel.: 069/798-29317
Email: roehm[at]pharmchem.uni-frankfurt.de

Sebastian Mandel
PhD student

Raum: N240/2.10

Tel.: 069/798-29496
E-mail: mandel[at]pharmchem.uni-frankfurt.de


 

Guiqun Wang
PhD student

Raum: N100/2.11

Tel.: 069/798-29307
E-mail:Wang[at]pharmchem.uni-frankfurt.de

Alumni

Apirat Chaikuad (2014 - 2022)

Christian Kurz (2017 -2021)

Tim Weiser (2016 -2021)

Anja Dölle (2017 - 2021)

Nadine Ruß (2016 - 2021)

Rosa Aghighi (2019 - 2021)

Martin Schröder (2016 - 2021)

Marek Wanior (2015 - 2021)

Kathrin Cartsburg (2014 - 2021)

Roberta Tesch (2018 - 2021)

Leonore Novak (2020 - 2021)

Romain Lucas (2018 - 2020)

Anaïs Lucas (2018 - 2020)

Claire Mestdagh (2019 - 2020)

Mishal McAuley (2017 - 2020)

David Heidenreich (2016 - 2019)