ResearcherID H-3178-2011

Original Articles

  1. 1H, 13C, and 15N backbone chemical shift assignments of the C-terminal dimerization domain of SARS-CoV-2 nucleocapsid protein
    Korn SM, Lambertz R, Fürtig B, Hengesbach M, Löhr F, Richter C, Schwalbe H, Weigand JE, Wöhnert J, Schlundt A
    Biomol NMR Assign. 2020 Dec 3:1-7.
    doi: 10.1007/s12104-020-09995-y
  2. Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy
    Wacker A*, Weigand JE*, Akabayov SR, Altincekic N, Bains JK, Banijamali E, Binas O, Castillo-Martinez J, Cetiner E, Ceylan B, Chiu LY, Davila-Calderon J, Dhamotharan K, Duchardt-Ferner E, Ferner J, Frydman L, Fürtig B, Gallego J, Grün JT, Hacker C, Haddad C, Hähnke M, Hengesbach M, Hiller F, Hohmann KF, Hymon D, de Jesus V, Jonker H, Keller H, Knezic B, Landgraf T, Löhr F, Luo L, Mertinkus KR, Muhs C, Novakovic M, Oxenfarth A, Palomino-Schätzlein M, Petzold K, Peter SA, Pyper DJ, Qureshi NS, Riad M, Richter C, Saxena K, Schamber T, Scherf T, Schlagnitweit J, Schlundt A, Schnieders R, Schwalbe H, Simba-Lahuasi A, Sreeramulu S, Stirnal E, Sudakov A, Tants JN, Tolbert BS, Vögele J, Weiß L, Wirmer-Bartoschek J, Wirtz Martin MA, Wöhnert J, Zetzsche H.
    Nucleic Acids Res. 2020 Dec 16;48(22):12415-12435. Labeled as Breakthrough Paper by NAR
    doi: 10.1093/nar/gkaa1013
  3. Structural dynamics govern substrate recruitment and catalytic turnover in H/ACA RNP pseudouridylation
    Schmidt A*, Hanspach G*, Hengesbach M.
    RNA Biol. 2020 Nov 10:1-10.
    doi: 10.1080/15476286.2020.1842984
  4. 1H, 13C, and 15N backbone chemical shift assignments of coronavirus-2 non-structural protein Nsp10
    Kubatova N, Qureshi NS, Altincekic N, Abele R, Bains JK, Ceylan B, Ferner J, Fuks C, Hargittay B, Hutchison MT, de Jesus V, Kutz F, Wirtz Martin MA, Meiser N, Linhard V, Pyper DJ, Trucks S, Fürtig B, Hengesbach M#, Löhr F, Richter C, Saxena K, Schlundt A, Schwalbe H#, Sreeramulu S, Wacker A, Weigand JE, Wirmer-Bartoschek J, Wöhnert J.
    Chemistry – A European Journal, 26 (8), 1800-1810 (Highlighted with Journal Cover)
    doi: 10.1002/chem.201904623
  5. RNA secondary structure dependence in METTL3-METTL14 mRNA methylation is modulated by the N-terminal domain of METTL3
    Meiser N, Mench N, Hengesbach M
    Biol Chem. 2020 Oct 19:/j/bchm.ahead-of-print/hsz-2020-0265/hsz-2020-0265.xml.
    doi: 10.1515/hsz-2020-0265
  6. 1H, 13C, and 15N backbone chemical shift assignments of the apo and the ADP-ribose bound forms of the macrodomain of SARS-CoV-2 non-structural protein 3b
    Cantini F, Banci L, Altincekic N, Bains JK, Dhamotharan K, Fuks C, Fürtig B, Gande SL, Hargittay B, Hengesbach M, Hutchison MT, Korn SM, Kubatova N, Kutz F, Linhard V, Löhr F, Meiser N, Pyper DJ, Qureshi NS, Richter C, Saxena K, Schlundt A, Schwalbe H, Sreeramulu S, Tants JN, Wacker A, Weigand JE, Wöhnert J, Tsika AC, Fourkiotis NK,
    Spyroulias GA
    Biomol NMR Assign.2020 Oct;14(2):339-346.
    doi: 10.1007/s12104-020-09973-4.
  7. 1H, 13C, and 15N backbone chemical shift assignments of the nucleic acid-binding domain of
    SARS-CoV-2 non-structural protein 3e.
    Korn SM, Dhamotharan K, Fürtig B, Hengesbach M, Löhr F, Qureshi NS, Richter C, Saxena K, Schwalbe H, Tants JN, Weigand JE, Wöhnert J, Schlundt A.
    Biomol NMR Assign.2020 Oct;14(2):329-333.
    doi: 10.1007/s12104-020-09971-6
  8. The protective role of m1A during stress-induced granulation
    Alriquet M, Calloni G, Martínez-Limón A, Ponti RD, Hanspach GHengesbach M, Tartaglia GG, Vabulas RM
    J Mol Cell Biol. 2020 May 27:mjaa023.
    doi: 10.1093/jmcb/mjaa023
  9. Site-Specific Detection of Arginine Methylation in Highly Repetitive Protein Motifs of
    Low Sequence Complexity by NMR
    Altincekic N, Löhr F, Meier-Credo J, Langer JD, Hengesbach M, Richter C, Schwalbe H.
    J Am Chem Soc. 2020 Apr 22;142(16):7647-7654.
    doi: 10.1021/jacs.0c02308
  10. Genetic Code Expansion Facilitates Position-Selective Labeling of RNA for Biophysical Studies
    Hegelein, D. Müller, S. Größl, M. Göbel, M. Hengesbach, H. Schwalbe
    Chemistry – A European Journal, 26 (8), 1800-1810 (Highlighted with Journal Cover)
    doi: 10.1002/chem.201904623
  11. Assembly of Proteins by Free RNA during the Early Phase of Proteostasis Stress
    Alriquet M., A. Martínez-Limón, G. Hanspach,M. Hengesbach, G. G Tartaglia, G. Calloni, R.M. Vabulas
    J Proteome Res. 2019;18(7):2835–2847. doi:10.1021/acs.jproteome.9b00143
  12. Combined smFRET and NMR analysis of riboswitch structural dynamics
    Bains JK*, J. Blechar*, V. de Jesus*,  Meiser*, H. Zetzsche, B. Fürtig, H. Schwalbe,and M. Hengesbach
    Methods, 2019 Jan 15;153:22-34. doi: 10.1016/j.ymeth.2018.10.004
  13. The Protein Microenvironment Governs the Suitability of Labeling Sites for Single-Molecule Spectroscopy of RNP Complexes
    Schmidt A
    , N. Altincekic, H. Gustmann, J. Wachtveitl and  Hengesbach
    ACS Chem Biol, 2018 13(9): 2472-2483
  14. NMR Structural Profiling of Transcriptional Intermediates Reveals Riboswitch Regulation by Metastable RNA Conformations
    Helmling, A. Wacker, M.T. Wolfinger, I.L. Hofacker,  Hengesbach, B. Fürtig, and H. Schwalbe
    JACS, 2017 Feb. 139(7):2647-2656
  15. Ligand-modulated folding of the full-length adenine riboswitch probed by NMR and single-molecule FRET spectroscopy
    Warhaut, K.R. Mertinkus, P. Höllthaler, B. Fürtig,M. Heilemann, Hengesbach, and H. Schwalbe
    Nucleic Acids Res.2017 Feb 15. doi: 10.1093/nar/gkx110
  16. Rapid NMR screening of RNA secondary structure and binding
    Helmling C, Keyhani S, Sochor F, Fürtig B, Hengesbach M, Schwalbe H.
    J Biomol NMR. 2015 Sep;63(1):67-76. doi: 10.1007/s10858-015-9967-y.
  17. Differential Scanning Fluorimetry for Monitoring RNA Stability
    Silvers, H. Keller, H. Schwalbe and M. Hengesbach
    ChemBioChem, 2015 May 7; (7)16: 1014.
    Highlighted as Inside Cover
  18. Single molecule FRET reveals a rugged folding energy landscape for the human telomerase RNA pseudoknot domain
    , N.-K. Kim, J. Feigon, and M.D. Stone
    Angewandte Chemie International Edition, 2012 Jun 11;51(24):5876-9.
  19. Single-molecule FRET reveals a cooperative effect of two methyl group modifications in the folding of human mitochondrial tRNALys
    Yu. Kobitski, M. Hengesbach, S. Seidu-Larry, K. Dammertz, C. S. Chow, A. van Aerschot, G.U. Nienhaus and M. Helm
    Chemistry & Biology, 2011 Jul 29;18(7):928-36
  20. Single-molecule FRET studies of counterion effects on the free energy landscape of human mitochondrial lysine tRNA
    Dammertz, M. Hengesbach, M. Helm, G.U. Nienhaus, and A. Yu.Kobitski
    Biochemistry, 2011 Apr 19;50(15):3107-15
  21. Formation of a stalled early intermediate of Pseudouridine synthesis monitored by real-time FRET
    , F. Voigts-Hoffmann, B. Hofmann and M. Helm
    RNA, 2010 Mar;16(3):610-20.
  22. Sculpting an RNA conformational energy landscape by a methyl group modification - a single-molecule FRET study
    Yu. Kobitski, M. Hengesbach, M. Helm, and G.U. Nienhaus
    Angewandte Chemie International Edition, 2008. 47(23): p. 4326-30
    (Arbeit in deutscher Sprache:Angewandte Chemie, 2008. 120(23): p. 4398-4402)
  23. Use of DNAzymes for site-specific analysis of ribonucleotide modifications
    , M. Meusburger*, F. Lyko and M. Helm
    RNA, 2008. 14(1): p. 180-7
  24. A Methyl Group Controls Conformational Equilibrium in Human Mitochondrial tRNALys
    Voigts-Hoffmann, M. Hengesbach, A. Yu. Kobitski, A. van Aerschot, P. Herdewijn, G.U. Nienhaus, and M. Helm
    JACS, 2007. 129(44): p. 13382-3


Reviews & Methods

R8. NMR Spectroscopy of Large Functional RNAs:
       From Sample Preparation to Low-Gamma Detection
Schnieders R, Knezic B, Zetzsche H, Sudakov A, Matzel T, Richter C, Hengesbach M, Schwalbe H, Fürtig B
       Current Protocols in Nucleic Acid Chemistry. 2020 Sep;82(1):e116.
       doi: 10.1002/cpnc.116

R7. Genetic Code Expansion Facilitates Position-Selective
       Modification of Nucleic Acids and Proteins
Müller D, Trucks S, Schwalbe H, Hengesbach M.
Chempluschem. 2020 Jun;85(6):1233-1243.
       doi: 10.1002/cplu.202000150

R6. Cooperative Analysis of Structural Dynamics in RNA-Protein Complexes by
       Single-Molecule Förster Resonance Energy Transfer Spectroscopy
       Meiser N, Fuks C, Hengesbach M.
Molecules. 2020 Apr 28;25(9):2057.
       doi: 10.3390/molecules25092057

R5. Strategic labelling approaches for RNA single-molecule spectroscopy
       Hanspach G, Trucks S, Hengesbach M.
       RNA Biology. 2019 Mar 15:1-14. doi: 10.1080/15476286.2019.1593093.

R4. Single-molecule Analysis of Telomerase Structure and Function
       M. Hengesbach
, B.M. Akiyama, and M.D. Stone
       Current Opinion in Chemical Biology, 2011 Dec;15(6):845-52.

R3. A post-labeling Approach for the Characterization and Quantification of RNA
      modifications Based on Site-directed Cleavage by DNAzymes

        M. Meusburger*, M. Hengesbach*, and M. Helm
Methods in Molecular Biology: DNA and RNA editing, 2011, 718; p259-70

 R2. RNA Intramolecular Dynamics by Single-Molecule FRET
       M. Hengesbach
, A. Kobitski, F. Voigts-Hoffmann, C. Frauer, G.U. Nienhaus, and M. Helm
        Current Protocols in Nucleic Acid Chemistry
, Sep 2008, Chapter 11; Unit 11.12

R1. Exploring the folding free energy landscape of small RNA molecules by single-pair
       Förster resonance energy transfer
A. Yu. Kobitski, A.  Nierth, M. Hengesbach, A.  Jäschke, M. Helm, and G.Ulrich Nienhaus
        Biophysical Reviews and Letters
, 2008. 3(4): p. 439-457.

Book Chapters

B1. Handbook of RNA Biochemistry, 2nd edition
       Herausgeber: Prof. Roland K. Hartmann
      Kapitel zur Ligation von RNA, im Druck


C2. The how & why of looking at individual RNAs
       Hengesbach M., 
RNA Biol. 2019;16(9):1075–1076.

C1. Structural basis for regulation of ribosomal RNA 2'-O-methylation
       M. Hengesbach
, H. Schwalbe
       Angewandte Chemie International Edition, 2014 Feb 10;53(7):1742-4
       (Arbeit in deutscher Sprache: Angewandte Chemie, 2014. 126(7): p. 1770-1772)

 *: joint first authors