Original- und Übersichtsarbeiten 2011-2015

Anatomie I


Becker D, Deller T, Vlachos A (2015) Tumor necrosis factor (TNF)-receptor 1 and 2 mediate homeostatic synaptic plasticity of denervated mouse dentate granule cells. Sci Rep-Uk, 5: 12726

Hennchen M, Stubbusch J, Abarchan-El Makhfi I, Kramer M, Deller T, Pierre-Eugene C, Janoueix-Lerosey I, Delattre O, Ernsberger U, Schulte JB, Rohrer H (2015) Lin28B and Let-7 in the Control of Sympathetic Neurogenesis and Neuroblastoma Development. J Neurosci, 35: 16531-16544

Jedlicka P, Benuskova L, Abraham WC (2015) A Voltage-Based STDP Rule Combined with Fast BCM-Like Metaplasticity Accounts for LTP and Concurrent "Heterosynaptic" LTD in the Dentate Gyrus In Vivo. Plos Comput Biol, 11: e1004588

Jedlicka P, Vnencak M, Krueger DD, Jungenitz T, Brose N, Schwarzacher SW (2015) Neuroligin-1 regulates excitatory synaptic transmission, LTP and EPSP-spike coupling in the dentate gyrus in vivo. Brain Struct Funct, 220: 47-58

Lenz M, Platschek S, Priesemann V, Becker D, Willems LM, Ziemann U, Deller T, Müller-Dahlhaus F, Jedlicka P, Vlachos A (2015) Repetitive magnetic stimulation induces plasticity of excitatory postsynapses on proximal dendrites of cultured mouse CA1 pyramidal neurons. Brain Struct Funct, 220: 3323-3337

Mazzoni A, Lindén H, Cuntz H, Lansner A, Panzeri S, Einevoll GT (2015) Computing the Local Field Potential (LFP) from Integrate-and-Fire Network Models. Plos Comput Biol, 11: e1004584

Radic T, Al-Qaisi O, Jungenitz T, Beining M, Schwarzacher SW (2015) Differential Structural Development of Adult-Born Septal Hippocampal Granule Cells in the Thy1-GFP Mouse, Nuclear Size as a New Index of Maturation. Plos One, 10: e0135493

Rüb U, Stratmann K, Heinsen H, Del Turco D, Ghebremedhin E, Seidel K, den Dunnen W, Korf HW (2015) Hierarchical Distribution of the Tau Cytoskeletal Pathology in the Thalamus of Alzheimer's Disease Patients. J Alzheimers Dis, 49: 905-915

Rüb U, Seidel K, Vonsattel J, Lange H, Eisenmenger W, Götz M, Del Turco D, Bouzrou M, Korf H, Heinsen H (2015) Huntington's disease (HD): Neurodegeneration of Brodmann's primary visual area 17 (BA17). Brain Pathol, 25: 701-711

Stein ES, Itsekson-Hayosh Z, Aronovich A, Reisner Y, Bushi D, Pick CG, Tanne D, Chapman J, Vlachos A, Maggio N (2015) Thrombin induces ischemic LTP (iLTP): implications for synaptic plasticity in the acute phase of ischemic stroke. Sci Rep-Uk, 5: 7912

Tosovic D, Seidl L, Ghebremedhin E, Brown MJ (2015) Determining minimal stimulus intensity for mechanomyographic analysis. J Electromyogr Kines, 25: 749-753

Vnencak M, Paul MH, Hick M, Schwarzacher SW, Del Turco D, Müller UC, Deller T, Jedlicka P (2015) Deletion of the amyloid precursor-like protein 1 (APLP1) enhances excitatory synaptic transmission, reduces network inhibition but does not impair synaptic plasticity in the mouse dentate gyrus. J Comp Neurol, 523: 1717-1729

Ben Shimon M, Lenz M, Ikenberg B, Becker D, Shavit Stein E, Chapman J, Tanne D, Pick CG, Blatt I, Neufeld M, Vlachos A, Maggio N (2015) Thrombin regulation of synaptic transmission and plasticity: implications for health and disease. Front Cell Neurosci, 9: 151

Lenz M, Vlachos A, Maggio N (2015) Ischemic long-term-potentiation (iLTP): perspectives to set the threshold of neural plasticity toward therapy. Neural Regen Res, 10: 1537-9


Del Turco D, Schlaudraff J, Bonin M, Deller T (2014) Upregulation of APP, ADAM10 and ADAM17 in the Denervated Mouse Dentate Gyrus. PLoS One, 9: e84962

Jedlicka P, Vnencak M, Krueger DD, Jungenitz T, Brose N, Schwarzacher SW (2014) Neuroligin-1 regulates excitatory synaptic transmission, LTP and EPSP-spike coupling in the dentate gyrus in vivo. Brain Struct Funct [Epub ahead of print]

Jungenitz T, Radic T, Jedlicka P, Schwarzacher SW (2014) High-Frequency Stimulation Induces Gradual Immediate Early Gene Expression in Maturing Adult-Generated Hippocampal Granule Cells. Cereb Cortex [Epub ahead of print]

Lötsch J, Schaeffeler E, Mittelbronn M, Winter S, Gudziol V, Schwarzacher SW, Hummel T, Doehring A, Schwab M, Ultsch A (2014) Functional genomics suggest neurogenesis in the adult human olfactory bulb. Brain Struct Funct [Epub ahead of print]


Baj G, Del Turco D, Schlaudraff J, Torelli L, Deller T, Tongiorgi E (2013) Regulation of the spatial code for BDNF mRNA isoforms in the rat hippocampus following pilocarpine-treatment: a systematic analysis using laser microdissection and quantitative real-time PCR. Hippocampus, 23: 413-423

Becker D, Zahn N, Deller T, Vlachos A (2013) Tumor necrosis factor alpha maintains denervation-induced homeostatic synaptic plasticity of mouse dentate granule cells. Front Cell Neurosci, 7: 257

Cuntz H, Forstner F, Schnell B, Ammer G, Raghu SV, Borst A (2013) Preserving neural function under extreme scaling. PLoS One, 8: e71540

Maggio N, Blatt I, Vlachos A, Tanne D, Chapman J, Segal M (2013) Treating seizures and epilepsy with anticoagulants? Front Cell Neurosci, 7: 19

Majdazari A, Stubbusch J, Müller CM, Hennchen M, Weber M, Deng CX, Mishina Y, Schütz G, Deller T, Rohrer H (2013) Dendrite complexity of sympathetic neurons is controlled during postnatal development by BMP signaling. J Neurosci, 33: 15132-15144

Meltendorf C, Deller T, Ackermann H, von Pape U (2013) Reply to the letter by Zhang and Hoffman: Comments on corneal intrastromal tissue modeling with the femtosecond laser. Graef Arch Clin Exp, 251: 379-380

Müller-Dahlhaus F, Vlachos A (2013) Unraveling the cellular and molecular mechanisms of repetitive magnetic stimulation. Front Mol Neurosci, 6: 50

Pietzner J, Baer PC, Duecker RP, Merscher MB, Satzger-Prodinger C, Bechmann I, Wietelmann A, Del Turco D, Doering C, Kuci S, Bader P, Schirmer S, Zielen S, Schubert R (2013) Bone marrow transplantation improves the outcome of Atm-deficient mice through the migration of ATM-competent cells. Hum Mol Genet, 22: 493-507

Priester M, Copanaki E, Vafaizadeh V, Hensel S, Bernreuther C, Glatzel M, Seifert V, Groner B, Kögel D, Weissenberger J (2013) STAT3 silencing inhibits glioma single cell infiltration and tumor growth. Neuro Oncol, 15: 840-852

Rüb U, Hoche F, Brunt E, Heinsen H, Seidel K, Del Turco D, Paulson H, Bohl J, von Gall C, Vonsattel J, Korf H, den Dunnen W (2013) Degeneration of the cerebellum in Huntington's disease (HD): Possible relevance for the clinical picture and potential gateway to pathological mechanisms of the disease process. Brain Pathol, 23: 165-177

Rüb U, Schöls L, Paulson H, Auburger G, Kermer P, Jen JC, Seidel K, Korf HW, Deller T (2013) Clinical features, neurogenetics and neuropathology of the polyglutamine spinocerebellar ataxias type 1, 2, 3, 6 and 7. Prog Neurobiol, 104: 38-66

Vlachos A, Helias M, Becker D, Diesmann M, Deller T (2013) NMDA-receptor inhibition increases spine stability of denervated mouse dentate granule cells and accelerates spine density recovery following entorhinal denervation in vitro. Neurobiol Dis, 59: 267-276

Vlachos A, Ikenberg B, Lenz M, Becker D, Reifenberg K, Bas-Orth C, Deller T (2013) Synaptopodin regulates denervation-induced homeostatic synaptic plasticity. Proc Natl Acad Sci USA, 110: 8242-8247

Vlachos A, Reddy-Alla S, Papadopoulos T, Deller T, Betz H (2013) Homeostatic Regulation of Gephyrin Scaffolds and Synaptic Strength at Mature Hippocampal GABAergic Postsynapses. Cereb Cortex, 23: 2700-2711


Becker D, Willems LM, Vnencak M, Zahn N, Schuldt G, Jedlicka P, Maggio N, Deller T, Vlachos A (2012) Functional and structural properties of dentate granule cells with hilar basal dendrites in mouse entorhino-hippocampal slice cultures. PLoS One, 7: e48500

Benuskova L, Jedlicka P (2012) Computational modelling of long-term depression of synaptic weights: insights from STDP, metaplasticity and spontaneous activity. Neural Network World, 22: 161-180

Cernescu M, Stark T, Kalden E, Kurz C, Leuner C, Deller T, Göbel MW, Eckert GP, Brutschy B (2012) Laser-induced liquid bead ion desorption mass spectrometry: an approach to precisely monitor the oligomerization of the ß-amyloid peptide. Anal Chem, 84: 5276-5284

Cuntz H (2012) The dendritic density field of a cortical pyramidal cell. Front Neuroanat, 6: 2

Damrath E, Heck MV, Gispert S, Azizov M, Nowock J, Seifried C, Rüb U, Walter M, Auburger G (2012) ATXN2-CAG42 Sequesters PABPC1 into Insolubility and Induces FBXW8 in Cerebellum of Old Ataxic Knock-In Mice. Plos Genet, 8: e1002920

Hoche F, Seidel K, Theis M, Vlaho S, Schubert R, Zielen S, Kieslich M (2012) Neurodegeneration in ataxia telangiectasia: what is new? What is evident? Neuropediatrics, 43: 119-129

Jedlicka P, Owen M, Vnencak M, Tschäpe JA, Hick M, Müller UC, Deller T (2012) Functional consequences of the lack of amyloid precursor protein in the mouse dentate gyrus in vivo. Exp Brain Res, 217: 441-447

Joshi KB, Vlachos A, Mikat V, Deller T, Heckel A (2012) Light-activatable molecular beacons with a caged loop sequence. Chem Commun, 48: 2746-2748

Jungblut D, Vlachos A, Schuldt G, Zahn N, Deller T, Wittum G (2012) SpineLab: tool for three-dimensional reconstruction of neuronal cell morphology. J Biomed Opt, 17: 076007

Kallenborn-Gerhardt W, Lu R, Lorenz J, Gao W, Weiland J, Del Turco D, Deller T, Laube B, Betz H, Geisslinger G, Schmidtko A (2012) Prolonged zymosan-induced inflammatory pain hypersensitivity in mice lacking glycine receptor alpha2. Behav Brain Res, 226: 106-111

Kallenborn-Gerhardt W, Schröder K, Del Turco D, Lu R, Kynast K, Kosowski J, Niederberger E, Shah AM, Brandes RP, Geisslinger G, Schmidtko A (2012) NADPH oxidase-4 maintains neuropathic pain after peripheral nerve injury. J Neurosci, 32: 10136-45

Kögel D, Deller T, Behl C (2012) Roles of amyloid precursor protein family members in neuroprotection, stress signaling and aging. Exp Brain Res, 217: 471-479

Lebedeva E, Stingl JC, Thal DR, Ghebremedhin E, Strauss J, Ozer E, Bertram L, von Einem B, Tumani H, Otto M, Riepe MW, Högel J, Ludolph AC, von Arnim CAF (2012) Genetic variants in PSEN2 and correlation to CSF ß-amyloid42 levels in AD. Neurobiol Aging, 33: 201.e9-18

Miroci H, Schob C, Kindler S, Ölschläger-Schütt J, Fehr S, Jungenitz T, Schwarzacher SW, Bagni C, Mohr E (2012) Makorin ring zinc finger protein 1 (MKRN1), a novel poly(A)-binding protein-interacting protein, stimulates translation in nerve cells. J Biol Chem, 287: 1322-1334

Müller UC, Pietrzik CU, Deller T (2012) The physiological functions of the ß-amyloid precursor protein APP. Exp Brain Res, 217: 325-329

Rüb U, Bürk K, Timmann D, den Dunnen W, Seidel K, Brunt E, Heinsen H, Egensperger R, Bornemann A, Schwarzacher S, Korf HW, Schöls L, Bohl J, Deller T (2012) Spinocerebellar ataxia type 1 (SCA1): New pathoanatomical and clinico-pathological insights. Neuropath Appl Neuro, 38: 665-680

Scherzed W, Brunt ER, Heinsen H, de Vos RA, Seidel K, Bürk K, Schöls L, Auburger G, Del Turco D, Deller T, Korf HW, den Dunnen WF, Rüb U (2012) Pathoanatomy of Cerebellar Degeneration in Spinocerebellar Ataxia Type 2 (SCA2) and Type 3 (SCA3). Cerebellum, 11: 749-760

Schwarzacher SW, Rüb U, Deller T (2012) Response to Fernagut et al.: The ambiguous nucleus ambiguus. Brain, 135: e206

Vlachos A (2012) Synaptopodin and the spine apparatus organelle-Regulators of different forms of synaptic plasticity? Ann Anat, 194: 317-320

Vlachos A, Becker D, Jedlicka P, Winkels R, Roeper J, Deller T (2012) Entorhinal denervation induces homeostatic synaptic scaling of excitatory postsynapses of dentate granule cells in mouse organotypic slice cultures. Plos One, 7: e32883

Vlachos A, Orth CB, Schneider G, Deller T (2012) Time-lapse imaging of granule cells in mouse entorhino-hippocampal slice cultures reveals changes in spine stability after entorhinal denervation. J Comp Neurol, 520: 1891-902


Eckert GP, Chang S, Eckmann J, Copanaki E, Hagl S, Hener U, Müller WE, Kögel D (2011) Liposome-incorporated DHA increases neuronal survival by enhancing non-amyloidogenic APP processing. BBA-Biomembranes, 1808: 236-243

Ferreira A, Marguti I, Bechmann I, Jeney V, Chora A, Palha NR, Rebelo S, Henri A, Beuzard Y, Soares MP (2011) Sickle hemoglobin confers tolerance to Plasmodium infection. Cell, 145: 398-409

Fork C, Bauer T, Golz S, Geerts A, Weiland J, Del Turco D, Schömig E, Gründemann D (2011) OAT2 catalyses efflux of glutamate and uptake of orotic acid. Biochem J, 436: 305-312

Glaschke A, Weiland J, Del Turco D, Steiner M, Peichl L, Glösmann M (2011) Thyroid hormone controls cone opsin expression in the retina of adult rodents. J Neurosci, 31: 4844-4851 

Heine S, Michalakis S, Kallenborn-Gerhardt W, Lu R, Lim HY, Weiland J, Del Turco D, Deller T, Tegeder I, Biel M, Geisslinger G, Schmidtko A (2011) CNGA3: a target of spinal nitric oxide/cGMP signaling and modulator of inflammatory pain hypersensitivity. J Neurosci, 31: 11184-11192

Hoche F, Balikó L, den Dunnen W, Steinecker K, Bartos L, Sáfrány E, Auburger G, Deller T, Korf HW, Klockgether T, Rüb U, Melegh B (2011) Spinocerebellar Ataxia Type 2 (SCA2): Identification of Early Brain Degeneration in One Monozygous Twin in the Initial Disease Stage.Cerebellum, 10: 245-253

Hundelt M, Fath T, Selle K, Oesterwind K, Jordan J, Schultz C, Götz J, von Engelhardt J, Monyer H, Lewejohann L, Sachser N, Bakota L, Brandt R (2011) Altered phosphorylation but no neurodegeneration in a mouse model of tau hyperphosphorylation. Neurobiol Aging, 32: 991-1006

Jedlicka P, Hoon M, Papadopoulos T, Vlachos A, Winkels R, Poulopoulos A, Betz H, Deller T, Brose N, Varoqueaux F, Schwarzacher SW (2011) Increased Dentate Gyrus Excitability in Neuroligin-2-Deficient Mice in Vivo. Cereb Cortex, 21: 357-367

Jedlicka P, Deller T, Gutkin BS, Backus KH (2011) Activity-dependent intracellular chloride accumulation and diffusion controls GABA(A) receptor-mediated synaptic transmission. Hippocampus, 21: 885-898

Lebedeva E, Stingl JC, Thal DR, Ghebremedhin E, Strauss J, Ozer E, Bertram L, von Einem B, Tumani H, Otto M, Riepe MW, Högel J, Ludolph AC, von Arnim CAF (2011) Genetic variants in PSEN2 and correlation to CSF -amyloid42 levels in AD. Neurobiol Aging, 33: 201

Meltendorf C, Deller T, Ackermann H, von Pape U (2011) Reply to the letter by Zhang and Hoffman: Comments on corneal intrastromal tissue modeling with the femtosecond laser. Graef Arch Clin Exp, [Epub ahead of print]

Meltendorf C, Deller T, Ackermann H, von Pape U. (2011) Corneal intrastromal tissue modeling with the femtosecond laser. Graefes Arch Clin Exp Ophthalmol. 249: 1661-1666

Prodinger C, Bunse J, Krüger M, Schiefenhövel F, Brandt C, Laman JD, Greter M, Immig K, Heppner F, Becher B, Bechmann I (2011) CD11c-expressing cells reside in the juxtavascular parenchyma and extend processes into the glia limitans of the mouse nervous system. Acta Neuropathol, 121: 445-458

Raasch J, Zeller N, van Loo G, Merkler D, Mildner A, Erny D, Knobeloch KP, Bethea JR, Waisman A, Knust M, Del Turco D, Deller T, Blank T, Priller J, Brück W, Pasparakis M, Prinz M (2011) IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system. Brain, 134: 1184-1198

Schwarzacher SW, Rüb U, Deller T (2011) Response to Fernagut et al.: The ambiguous nucleus ambiguus. Brain, Aug 22. [Epub ahead of print]

Schwarzacher SW, Rüb U, Deller T (2011) Neuroanatomical characteristics of the human pre-Bötzinger complex and its involvement in neurodegenerative brainstem diseases. Brain, 134: 24-35

Stubbusch J, Majdazari A, Schmidt M, Schütz G, Deller T, Rohrer H (2011) Generation of the tamoxifen-inducible DBH-Cre transgenic mouse line DBH-CT. Genesis, [Epub ahead of print]

Vuksic M, Del Turco D, Vlachos A, Schuldt G, Müller CM, Schneider G, Deller T (2011) Unilateral entorhinal denervation leads to long-lasting dendritic alterations of mouse hippocampal granule cells. Exp Neurol, 230: 176-185