Publikationen Prof. Erik Maronde

Original- und Übersichtsarbeiten | Buchartikel

2016 - 2021

Dumas G, Goubran-Botros H, Matondo M, Pagan C, Boulègue C, Chaze T, Chamot-Rooke J, Maronde E, Bourgeron T (2021) Mass-spectrometry analysis of the human pinealproteome during night and day and in autism. J Pineal Res, 70: e12713. doi: 10.1111/jpi.12713. Epub 2021 Jan 11. PMID: 33368564; PMCID: PMC8047921

Maronde E (2020) Influence of Phosphodiesterase Inhibition on CRE- and EGR1-Dependent Transcription in a Mouse Hippocampal Cell Line. Int J Mol Sci, 21: 8658. doi: 10.3390/ijms21228658. PMID: 33212816; PMCID: PMC7696530

Stenzinger M, Karpova D, Unterrainer C, Harenkamp S, Wiercinska E, Hoerster K, Pfeffer M, Maronde E, Bonig H (2019) Hematopoietic-Extrinsic Cues Dictate Circadian Redistribution of Mature and Immature Hematopoietic Cells in Blood and Spleen. Cells, 8: 1033. doi: 10.3390/cells8091033. PMID: 31491915; PMCID: PMC6769956.

Bahlmann O, Schürmann C, Maronde E (2019) Altered laryngeal morphology in Period1 deficient mice. Ann Anat, 223: 43-48

Maronde E (2018) Trehalose Activates CRE-Dependent Transcriptional Signaling in HT22 Mouse Hippocampal Neuronal Cells: A Central Role for PKA Without cAMP Elevation. Front Mol Neurosci, 11: 386

Kim P, Oster H, Lehnert H, Schmid SM, Salamat N, Barclay JL, Maronde E, Inder W, Rawashdeh O (2019) Coupling the Circadian Clock to Homeostasis: The Role of Period in Timing Physiology. Endocr Rev, 40: 66-95

Rawashdeh O, Parsons R, Maronde E (2018) Clocking In Time to Gate Memory Processes: The Circadian Clock Is Part of the Ins and Outs of Memory. Neural Plast, 2018:6238989. doi: 10.1155/2018/6238989

Benabou M, Rolland T, Leblond CS, Millot GA, Huguet G, Delorme R, Leboyer M, Pagan C, Callebert J, Maronde E, Bourgeron T (2017) Heritability of the melatonin synthesis variability in autism spectrum disorders. Sci Rep, 7: 17746

Pagan C, Goubran-Botros H, Delorme R, Benabou M, Lemière N, Murray K, Amsellem F, Callebert J, Chaste P, Jamain S, Fauchereau F, Huguet G, Maronde E, Leboyer M, Launay JM, Bourgeron T (2017) Disruption of melatonin synthesis is associated with impaired 14-3-3 and miR-451 levels in patients with autism spectrum disorders. Sci Rep, 7: 2096

Rawashdeh O, Jilg A, Maronde E, Fahrenkrug J, Stehle JH (2017) Period1 gates the circadian modulation of memory-relevant signaling in mouse hippocampus by regulating the nuclear shuttling of the CREB kinase pP90RSK. J Neurochem, 138: 731-745

2011 - 2015

Bechstein P, Rehbach NJ, Yuhasingham G, Schürmann C, Göpfert M, Kössl M, Maronde E (2014) The clock gene Period1 regulates innate routine behaviour in mice. Royal Society B, 2014 Jan 28. [accepted]

Benz AH, Renné C, Maronde E, Koch M, Grabiec U, Kallendrusch S, Rengstl B, Newrzela S, Hartmann S, Hansmann ML, Dehghani F (2013) Expression and functional relevance of cannabinoid receptor 1 in hodgkin lymphoma. PLoS One, 8: e81675

Botros HG, Legrand P, Pagan C, Bondet V, Weber P, Ben-Abdallah M, Lemière N, Huguet G, Bellalou J, Maronde E, Beguin P, Haouz A, Shepard W, Bourgeron T (2013) Crystal structure and functional mapping of human ASMT, the last enzyme of the melatonin synthesis pathway. J Pineal Res, 54: 46-57

Jäger K, Wolf S, Dobrowolny H, Steiner J, Nave H, Maronde E, Bogerts B, Bernstein HG (2013) Differential topochemistry of three cationic amino acid transporter proteins, hCAT1, hCAT2 and hCAT3, in the adult human brain. Amino Acids, 44: 423-433

Kim M, Fekadu J, Maronde E, Rami A (2013) Alleviation of autophagy by knockdown of Beclin-1 enhances susceptibility of hippocampal neurons to proapoptotic signals induced by amino acid starvation. Histochem Cell Biol, 139: 99-108

Schob S, Schicht M, Sel S, Stiller D, Kekulé AS, Paulsen F, Maronde E, Bräuer L (2013) The detection of surfactant proteins A, B, C and D in the human brain and their regulation in cerebral infarction, autoimmune conditions and infections of the CNS. PLoS One, 8: e74412

Wiebking N, Maronde E, Rami A (2013) Increased neuronal injury in clock gene Per-1 deficient-mice after cerebral ischemia. Curr Neurovasc Res, 10: 112-125

Wunderer F, Kühne S, Jilg A, Ackermann K, Sebesteny T, Maronde E, Stehle JH (2013) Clock gene expression in the human pituitary gland. Endocrinology, 154: 2046-2057

Rawashdeh O, Maronde E (2012) The hormonal Zeitgeber melatonin: role as a circadian modulator in memory processing. Front Mol Neurosci, 5: 27

Koch M, Kreutz S, Böttger C, Benz A, Maronde E, Ghadban C, Korf HW, Dehghani F (2011) Palmitoylethanolamide protects dentate gyrus granule cells via peroxisome proliferator-activated receptor-alpha. Neurotox Res, 19: 330-340

Maronde E, Saade A, Ackermann K, Goubran-Botros H, Pagan C, Bux R, Bourgeron T, Dehghani F, Stehle JH (2011) Dynamics in enzymatic protein complexes offer a novel principle for the regulation of melatonin synthesis in the human pineal gland. J Pineal Res., 51: 145-155

2006 - 2010

Benz A, Shajari M, Peruzki N, Dehghani F, Maronde E (2010) A novel mechanism for transient Egr-1 protein induction via FGF-1-induced MAPK phosphorylation and PKB/Akt-dephosphorylation in hippocampal neurons. Br J Pharmacol, 160: 1621-1630

Koch M, Kreutz S, Böttger C, Benz A, Maronde E, Ghadban C, Korf HW, Dehghani F (2010) Palmitoylethanolamide (PEA) protects dentate gyrus granule cells via peroxisome proliferator-activated receptor (PPAR)-alpha. Neurotoxicity Research, in press

Maronde E, Schilling AF, Seitz S, Schinke T, Schmutz I, van der Horst G, Amling M, Albrecht U (2010) The Clock Genes Period 2 and Cryptochrome 2 Differentially Balance Bone Formation. PLoS One, 5: e11527

John H, Maronde E, Forssmann WG, Meyer M, Adermann K (2008) N-terminal acetylation protects glucagon-like peptide GLP-1-(7-34)-amide from DPP-IV-mediated degradation retaining cAMP- and insulin-releasing capacity. Eur J Med Res, 13: 73-78

Motzkus D, Loumi S, Cadenas C, Vinson C, Forssmann WG, Maronde E (2007) Activation of human Period-1 by PKA or CLOCK/BMAL1 is conferred by separate signal transduction pathways. Chronobiol Int 24: 783-792

Maronde E, Pfeffer M, Glass Y, Stehle JH (2007) Transcription factor dynamics in pineal gland and liver of the Syrian hamster (Mesocricetus auratus) adapts to prevailing photoperiod. J Pineal Res 43:16-24

Stephan S, Bonaterra G, van de Flierdt J, Luomi S, Kramer FJ, Fehr M, Forssmann WG, Maronde E (2007) Intermittent administration of the circulating form of human parathyroid hormone (hPTH-1-37) prevents bone loss in ovariectomized rats. Eur J Med Res 12:13-20

Motzkus D, Schulz-Maronde S, Heitland A, Schulz A, Forssmann WG, Jübner M and Maronde E. (2006) The novel beta-defensin DEFB123 prevents lipopolysaccharide-mediated effects in vitro and in vivo. Fasebj 20:1701-2

2000 - 2005

Mitrovic V, Lüss H, Nitsche K, Forssmann K, Fricke K, Maronde E, Forssmann WG, Meyer M (2005) Effects of the Renal Natriuretic Peptide Urodilatin (INN: Ularitide) in Patients with Decompensated Chronic Heart Failure A Double-Blind, Placebo-Controlled, Ascending Dose Trial (2005) Am Heart J 150:1239

Fricke K, Schulz A, John H, Forssmann WG, Maronde E (2005) Isolation and characterisation of a novel POMC-derived peptide from hemofiltrate of chronic renal failure patients. Endocrinology 146: 2060-2068

Kutzleb C, Busmann A, Wendland M, Maronde E (2005) Discovery of Novel Regulatory Peptides by Reverse Pharmacology: Spotlight on Chemerin and the RF-amide Peptides Metastin and QRFP. In: Exploiting the Peptide Pool: New Structures, Novel Functions and Therapeutic Opportunities Guest Editor: Knut Adermann. Current Protein and Peptide Science 6: 265-278

Fricke K, Heitland A, Maronde E (2004)Cooperative activation of lipolysis by protein kinase A and protein kinase C pathways in 3T3-L1 adipocytes. Endocrinology 145: 4940-4947

Maronde E, Motzkus D (2003) Oscillation of human period 1 (hPER1) reporter gene activity in human neuroblastoma cells in vivo. Chronobiol Int 20: 671-681

Lammerich HP, Busmann A, Kutzleb C, Wendland M, Seiler P, Meyer U, Meyer M, Forssmann WG, Maronde (2003) Hemorphins VV-H-7 and LVV-H-7 activate the orphan bombesin type 3 receptor. British Journal of Pharmacology 138: 1431-1440

Krause A, Sillard R, Kleemeier B, Klüver E, Maronde E, Conejo-García JR, Forssmann WG, Schulz-Knappe P, Nehls MC, Wattler F, Wattler S, Adermann K (2003) Isolation and biochemical characterisation of LEAP-2, a novel blood peptide expressed in the liver. Protein Science 12: 143-152

Revermann M, Maronde E, Ruth P, Korf HW (2002) Protein kinase G Type I is colocalized with Arginine-Vasopressin in the Rat Suprachiasmatic Nucleus. Neuroscience Letters 334: 119-122

Schöniger S, Maronde E, Kopp MDA, Korf HW, Nürnberger F (2002) The transcription factor CREB and its stimulus-dependent phosphorylation in the bovine subcommissural organ, Cell Tissue Res 308: 131-142

Schöniger S, Kopp MDA, Schomerus C, Maronde E, Dehghani F, Meiniel A, Rodríguez EM, Korf HW, Nürnberger F (2002) Effects of neuroactive substances on the activity of subcommissural organ cells in dispersed cell and explant cultures. Cell Tissue Res 307: 101-114

Motzkus D, Albrecht U, Maronde E (2002) The human Per1 gene is inducible by interleukin-6. J Mol Neurosci 18: 105-109

Oster H, Maronde E, Albrecht U (2002) The Circadian Clock as a Molecular Calendar. Chronobiol Int 19: 507-516

Krause A, Liepke C, Meyer M, Adermann K, Forssmann WG, Maronde E (2001) Human natriuretic peptides exhibit antimicrobial activity. Eur J Med Res: 215-218

Hirsch J, Kruhoffer M, Adermann K, Heitland A, Maronde E, Meyer M, Forssmann WG, Herter P, Plenz G, Schlatter E (2001) Cellular localization, membrane distribution, and possible function of guanylate cyclases A and 1 in collecting ducts of rat. Cardiovascular Res 51: 553-561

Maronde E, Korf HW, Niemann P, Genieser HG (2001) Direct comparison of the potency of three novel cAMP analogs to induce CREB-phosphorylation in rat pinealocytes. J Pineal Res  31: 183-185

Motzkus D, Maronde E, Grunenberg U, Lee CC, Forssmann WG, Albrecht U (2000) The human PER1 gene is transcriptionally regulated by multiple signaling pathways. FEBS Lett 486: 315-319

Dehghani F, Maronde E, Schachmayer W, Korf HW (2000) Expression of neurofilament and its prognostic value in oligodendrogliomas. Acta Neuropathologia 100: 122-130

Kroeber S, Meissl H, Maronde E, Korf HW (2000) Analysis of signal transduction cascades reveal an essential role of calcium ions for the regulation of melatonin biosynthesis in the light sensitve pineal organ of the rainbow trout (Oncorhyncus mykiss). J Neurochem 74: 2478-2489

Kulaksiz H, Arnold R, Göke B, Maronde E, Meyer M, Fahrenholz F, Forssmann WG, Eissele R (2000) Expression and cell-specific localization of the cholecystokinin B/gastrin receptor in the human stomach. Cell Tiss Res 299: 289-298

Pfeffer M, Maronde E, Korf HW, Stehle JH (2000) Antisense experiments reveal molecular details on mechanisms of ICER suppressing cAMP-inducible genes in rat pinealocytes. J Pineal Res 29: 24-34

Schwede F, Maronde E, Genieser HG, Jastorff B (2000) Cyclic nucleotide analogs as biochemical tools and prospective drugs. Pharmacology and Therapeutics 87: 199-226

1992 - 1999

Maronde E, Wicht H, Tasken K, Olcese JM, Korf HW (1999) Melatonin biosynthesis in the rat pineal gland is regulated via cAMP-dependent protein kinase type II and phosphorylation of the transcription cAMP-regulated element binding protein. J Pineal Res 27: 170-182

Pfeffer M, Maronde E, Olcese JM, Korf HW, Stehle JH (1999) The transcription factor ICER is a natural reporter for cAMP-gated signal transduction pathways. Mol Pharmacol 56: 279-289

Maronde E, Pfeffer M, Molina CA, Olcese JM, Korf HW, Stehle JH (1999) Temporal gating of melatonin synthesis in rat pineal gland. J Neurosci 9: 3326-3336

Wicht H, Maronde E, Olcese JM, Korf HW (1999) The recording of dose-response curves in immunocytochemical preparations by semi-quantitative image analysis. Histochem Cytochem 47: 411-419

Maronde E, Pfeffer M, von Gall C, Dehghani F, Schomerus C, Kroeber S, Olcese J, Stehle J, Korf HW (1999) Adv Exp Med Biol 460: 109-131

Maronde E, Schomerus C, Stehle JH, Korf HW (1997) Control of CREB phosphorylation and its role for induction of melatonin synthesis in rat pinealocytes. Biology of the Cell 89: 511-515

Korf HW, Schomerus C, Maronde E, Stehle JH (1997) Role of calcium, p-CREB and ICER for signal transduction in the photoneuroendocrine pineal organ of mammals - Imaging of signal transduction mechanisms in the rat pineal organ. Naturwissenschaften 83: 535-543

Telgmann R, Maronde E, Tasken K, Gellersen B (1997) Activated protein kinase A is required for differentiation dependent transcription of the decidual prolactin gene expression in human endometrial stromal cells. Endocrinology 138: 929-937

Letz B, Schomerus C, Maronde E, Korf HW, Korbmacher C (1997) Electrical properties of isolated rat pinealocytes and functional evidence for a nicotinic acetylcholine receptor. J Physiol 499: 329-340

Maronde E, Middendorff R, Telgmann R, Tasken K, Hemmings B, Müller D, Olcese JM (1997) Melatonin synthesis in the bovine pineal gland is regulated by type II cyclic AMP-dependent protein. J Neurochem 68: 770-777

Schomerus C, Maronde E, Laedtke E, Korf HW (1996) Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) induce phosphorylation of the transcription factor CREB in subpopulations of rat pinealocytes: immunocytochemical and immunochemical evidence. Cell Tiss Res 286: 305-313

Middendorff R, Maronde E, Paust HJ, Müller D, Davidoff M, Olcese JM (1996) Expression of C-type natriuretic peptide (CNP) in the bovine pineal gland. J Neurochem 67: 517-524

Gjertsen BT, Mellgren G, Otten A, Maronde E, Genieser HG, Jastorff B, McKnight GS,  Doskeland SO (1995) Selective inhibition and activation of cAMP kinase I and II in intact cells by selective (Rp-) -cAMPS analogues. J Biol Chem 270: 20599-20607

Maronde E, Middendorff R, Mayer B, Olcese JM (1995) The effects of NO-Donors in bovine and rat pinealocytes: Stimulation of cGMP and cGMP-independent inhibition of melatonin production. J Neuroendocrinol 7: 207-214

Vintermyr OK, Gjertsen BT, Boe R, Maronde E, Aakvag A, Doskeland SO (1995) Forskolin and cAMP analogues inhibit MCF-7 cell growth by activation of cAMP dependent protein kinase. Roles of 8-Cl- and 8-amino-cAMP in cytotoxicity. Endocrinology 136: 2513-2520

Zorn M, Maronde E, Jastorff B, Richter-Landsberg C (1993) Differential effects of two structurally related N6-substituted cAMP analogues on C6 glioma cells. Eur J Cell Biol 60: 351-357

Musgrave IF, Genieser HG, Maronde E, Seifert R (1993) Preparations of Rp-cyclic adenosine 3',5'-phosphorothioate can contain biologically active amounts of adenosine. Febs Lett 318: 227-230

Richter-Landsberg C, Maronde E, Besser A (1993) Ecto-5'-Nucleotidase is synergistically modulated by Nerve Growth Factor and 8-Br-cAMP. Neurosci Res Comm 12: 51-56

Doskeland SO, Maronde E, Gjertsen BT (1993) The genetic subtypes of cAMP-dependent protein kinase - functionally different or redundant ? Biochem Biophys Acta 1178: 249–258

Yokozaki H, Tortora G, Pepe S, Maronde E, Genieser HG, Jastorff B, Cho-Chung YS (1992) Unhydrolyzable analogues of adenosine 3':5'-monophosphate demonstrating growth inhibition and differentiation in human cancer cells. Cancer Res 52: 2504-2508

Artikel und Bücher


Kutzleb C, Busmann A, Wendland M, Maronde E (2005) Discovery of Novel Regulatory Peptides by Reverse Pharmacology: Spotlight on Chemerin and the RF-amide Peptides Metastin and QRFP. In: Exploiting the Peptide Pool: New Structures, Novel Functions and Therapeutic Opportunities, Guest Editor: Knut Adermann. Current Protein and Peptide Science 6: 265-278

Korf HW, Schomerus C, Maronde E, Stehle JH (2001) Signal transduction in the rodent pineal organ: activation of membrane-bound receptors stimulates gene expression. In Perspective in Comparative Endocrinology: Unity and Diversity, HJT Goos, RK Rastogi, H Vaudry, R Pierantoni (Eds), Bologna, Monduzzi Editore: 63-71

Olcese JM, Maronde E (1997) Species heterogeneity in pineal signal transduction mechanisms. In: Pineal Update edited by S.M. Webb et al., PJD Publications Westbury, NY: 161- 171

Olcese JM, Middendorff R, Maronde E, Paust HJ, Davidoff M (1996) C-type natriuretic peptide (CNP) in the mammalian pineal gland: an endogenous autocrine peptide ? In: The peptidergic neuron: 297 - 302 Eds.: B. Krisch and R. Mentlein. Birkhäuser. Basel Boston Berlin

Jastorff B, Maronde E, van Bemmelen MXP, Zorn M, Störmann R (1992) Cyclic Nucleotide Metabolism as a target in Chemotherapy in: "Molecular Aspects of Chemotherapy", 3rd Int. Symp. 1991, Eds.: Shugar, Rode, Borowski: 73 - 104, PSP, Warzawa and Springer, New York