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Goethe University study on student learning outcomes during COVID-19-related school closures in spring 2020
Effects of remote learning during first lockdown comparable to summer vacation
How effectively do children and teenagers learn in remote classes from home? The issue has been the subject of intensive discussions, not only among experts. A systematic review from the Department of Educational Psychology at Goethe University provides a sobering answer for the spring of 2020. The situation seems to have later improved.
FRANKFURT. Despite diverse efforts to continue school operations as far possible with the help of remote learning and digital options during COVID-19-related schools closures, large deficits came about in the learning progress of many students. This was shown by a systematic review from Education Psychology at Goethe University. In the course of this systematic review, scientific databases were used to identify studies worldwide that examined the effect of COVID-19-related school closures on student achievement.
“We only included publications with appropriate research methods that allow evidence-based conclusions about the effect of COVID-19-related schools closures on student achievement, and that used testing instruments that are suitable for measuring student achievement," explains Professor Andreas Frey, who teaches Educational Psychology with a focus on consulting, measurement and evaluation at Goethe University, and is one of the authors of the study. This showed that, compared to pre-COVID-19 in-person teaching, average student achievement was significantly lower during school closures. “The average student achievement during the school closures in the spring of 2020 is best designated as stagnation, with a tendency toward losses comparable in size to the effect of summer vacation," says Frey. Observed losses in learning were particularly distinct for students from socio-economically disadvantaged homes. “The empirical evidence supports previous assumptions: The gap between rich and poor widened even more during the first COVID-19-related school closures," concludes Frey. However, there are also initial indications that the effects of the later school closures from winter 2020/21 onwards may not necessarily be as drastic. Online teaching has improved in many places, which seems to mitigate the negative effects.
The systematic review written by Svenja Hammerstein, Christoph König, Thomas Dreisörner and Andreas Frey is available as an open access preprint at https://psyarxiv.com/mcnvk/. The work is part of the project "Identifying and Reducing COVID-19-related Educational Disadvantages" (CoBi), which is funded by the Beisheim Foundation and the Goethe Coronavirus Fund. In the CoBi project, an online screening tool is being developed to identify particularly at-risk secondary school students, who are then supported by the MainKind counselling centre at Goethe University.
Publication: https://psyarxiv.com/mcnvk/
Further information
Professor Andreas Frey
Educational Psychology with a focus on consulting, measurement and evaluation
frey@psych.uni-frankfurt.de
Fear of long-term consequences – physical activity could actually help to better manage the pandemic
Physical activity levels and well-being sink worldwide during coronavirus restrictions – study led by Goethe University
During the first lockdown people were a good 40
percent less active, as shown by an international study led by Goethe University
Frankfurt. Psychological well-being sank as well; the portion of people at potential
risk for depression tripled. The authors fear long-term consequences and urge
that this be taken into account going forward.
FRANKFURT. Twenty
scientists from 14 countries warn of a hidden “pandemic within the pandemic“ in
two current publications. On the one hand, physical activity levels have gone
down significantly, on the other hand, psychological well-being has suffered.
“Governments and those responsible for health systems should take our findings
seriously," emphasizes the author team, headed by Dr Jan Wilke from the
Institute for Sport Sciences at Goethe University Frankfurt.
About 15,000 people in participating
countries answered standardised questionaires as part of an international
survey. In April/May 2020, they reported physical activity levels (13,500
participants) as well as their mental and physical well-being (15,000
participants) before and during the pandemic-related restrictions.
Older individuals especially affected
“The results show drastic reductions in
physical activity and well-being," says Wilke. More than two thirds of those
questioned were unable to maintain their usual level of activity. Moderate exercise
decreased by an average of 41 percent according to self-reported data - this
includes anything that increases heart rate and breathing, such as brisk
walking, running, cycling or even strenuous gardening.
The proportion of vigorous exercise during
which people sweat and clearly run out of breath fell by a similar amount (42
percent). The effects were somewhat higher among professional athletes and
particularly active people, as well as comparatively young and old people. The
decline in activity was particularly noticeable among people over 70 years of
age, who were 56 to 67 percent less active than before. "We know that
physical inactivity, especially in older people, can lead to changes that are
difficult to reverse after only two weeks - for example, in body fat percentage
or insulin sensitivity," warn the study authors.
Exercise helps prevents disease and reduces mortality
The WHO recommends at least 150 minutes of
moderate or 75 minutes of intensive physical activity per week - 81 percent of
the study participants achieved this before the pandemic, but only 63 percent
during the lockdowns. Yet sufficient exercise can reduce mortality by up to 39
per cent, as a 2015 study showed. Data suggests that too little exercise plays
a role in about one in ten premature deaths, because physical activity reduces
the likelihood of, for example, high blood pressure, metabolic disorders such
as type 2 diabetes, and cancer.
Exercise is known to activate the immune
system because it promotes blood circulation and activates lymphocytes and
messenger substances (cytokines) that are important for immune defence. Studies
show that physically active people are less susceptible to influenza, rhino and
herpes viruses and respiratory infections in general. So it may be that
exercise also offers protection against severe COVID-19 by reducing risk
factors such as obesity. Physical health and exercise also reduce the risk of
mental health problems such as depression and anxiety disorders.
Mental well-being drastically reduced
In another part of the study, the team of
authors asked about mental well-being during the pandemic restrictions. 73
percent of the study participants stated that their well-being had
deteriorated. The perceived quality of life as measured by the WHO well-being
Index, which measures mood, relaxation, activity, rest and interest, dropped on
average from 68 percent before the pandemic to 52 percent during the first
lockdown phase.
Above all, people felt less "active
and full of energy" and led a life less "filled with interesting
things". The proportion of very low scores indicating a possible risk of depression
tripled from 15 to 45 percent. "These effects were stronger among women
and younger people, " the study says. "More attention should be paid
to the needs of women in particular, as they are significantly more
vulnerable."
Nonetheless, 14 to 20 percent of the
respondents also stated that their health had improved - the authors see more
family time, greater work autonomy, fewer business trips or a changed
perception of health as possible reasons. "But a large part of the
population may still be suffering from barely visible health effects of the
pandemic," the team of authors warns.
This could also translate into rising
health costs: According to US data, the annual expenditure for inactive or
insufficiently active people increases by 1200 and 600 euros respectively -
this would add up to two to four million euros after one year just for the 3104
people from the survey who did not exercise enough during the lockdown.
The results of these first multinational
studies are likely to be relevant for an estimated four billion people
worldwide who were affected by the restrictions of the first coronavirus wave
in the spring of 2020. However, the data was predominantly collected through
electronic media, so populations without internet were not included. Also, no
differentiation was made according to factors such as living environment,
education and social status. In addition, the data is based on
self-assessments, not measurements, which may distort retrospective perceptions
in particular. "Nevertheless, our results show that the issues of physical
activity and well-being belong on the policy agenda," Wilke emphasises.
"Governmental and health-related
decison-makers need to develop strategies to mitigate the loss of physical
activity," write the authors. They suggest better public education,
creating exercise opportunities with a low likelihood of infection, or offering
effective home exercise programmes. Among numerous other health facets, this
would have a particularly positive effect on mental well-being.
Negative effects similar to those observed
in these studies should be avoided at all costs in future pandemics.
"Unfortunately, physical activity and exercise do not have a strong lobby
and are usually neglected in public discourse," says Wilke. "Yet they
can greatly help us to better cope with the pandemic."
Publications:
Jan Wilke et al. A Pandemic within the Pandemic? Physical Activity Levels Substantially
Decreased in Countries Affected by COVID-19. Int. J. Environ. Res. Public
Health, Vol. 18, 5 (2021), https://www.mdpi.com/1660-4601/18/5/2235/htm#B11-ijerph-18-02235
Jan Wilke et al., Drastic Reductions in Mental Well-Being Observed Globally During the
COVID-19 Pandemic: Results from the ASAP Survey. Front. Med. 8:578959
(2021), https://www.frontiersin.org/articles/10.3389/fmed.2021.578959/full
Further
information
Dr Jan Wilke
Institute für Sport Sciences
Goethe University Frankfurt
Tel. +49 (69) 798-24588,
wilke@sport.uni-frankfurt.de
https://www.uni-frankfurt.de/50765300/Arbeitsbereich_Sportmedizin_und_Leistungsphysiologie
Editor: Dr Markus Bernards, Science Editor, PR
& Communication Department, Tel: +49 (0) 69 798-12498, Fax: +49 (0) 69 798-763 12531, bernards@em.uni-frankfurt.de
80 percent of all SARS-CoV-2 proteins produced in the laboratory – protocols available for worldwide research - Goethe University Frankfurt forms the hub of research network from 17 countries
SARS-CoV-2 research accelerator: worldwide network headed by Goethe University develops protocols for laboratories
For the development of drugs or vaccines against
COVID-19, research needs virus proteins of high purity. For most of the
SARS-CoV-2 proteins, scientists at Goethe University Frankfurt and a total of
36 partner laboratories have now developed protocols that enable the production
of several milligrams of each of these proteins with high purity, and allow the
determination of the three-dimensional protein structures. The laboratory protocols
and the required genetic tools are freely accessible to researchers all over
the world.
FRANKFURT. When
the SARS-CoV-2 virus mutates, this initially only means that there is a change
in its genetic blueprint. The mutation may lead, for example, to an amino acid
being exchanged at a particular site in a viral protein. In order to quickly
assess the effect of this change, a three-dimensional image of the viral
protein is extremely helpful. This is because it shows whether the switch in amino
acid has consequences for the function of the protein - or for the interaction
with a potential drug or antibody.
Researchers at Goethe University Frankfurt
and TU Darmstadt began networking internationally from the very start of the
pandemic. Their goal: to describe the three-dimensional structures of
SARS-CoV-2 molecules using nuclear magnetic resonance spectroscopy (NMR). In
NMR spectroscopy, molecules are first labelled with special types of atoms
(isotopes) and then exposed to a strong magnetic field. NMR can then be used to
look in detail and with high throughput at how potentially active compounds
bind to viral proteins. This is done at the Centre for Biomolecular Magnetic
Resonance (BMRZ) at Goethe University and other locations. However, the basic
prerequisite is to produce large quantities of the proteins in high purity and
stability, and with their correct folding, for the large amount of tests.
The network, coordinated by Professor
Harald Schwalbe from the Institute of Organic Chemistry and Chemical Biology at
Goethe University, spans the globe. The elaboration of laboratory protocols for
the production of proteins is already the second milestone. In addition to
proteins, the virus consists of RNA, and the consortium already made all important RNA fragments of SARS-CoV-2 accessible last year. With the expertise of 129 colleagues,
it has now been possible to produce and purify 23 of the total of almost 30
proteins of SARS-CoV-2 completely or as relevant fragments "in the test
tube", and in large amounts.
For this purpose, the genetic information
for these proteins was incorporated into small, ring-shaped pieces of DNA
(plasmids). These plasmids were then introduced into bacteria for protein
production. Some special proteins were also produced in cell-free systems.
Whether these proteins were still correctly folded after their isolation and
enrichment was confirmed, among other things, by NMR spectroscopy.
Dr Martin Hengesbach from the Institute of
Organic Chemistry and Chemical Biology at Goethe University explains: "We
have isolated functional units of the SARS-CoV-2 proteins in such a way that
their structure, function and interactions can now be characterised by
ourselves and others. In doing so, our large consortium provides working
protocols that will allow laboratories around the world to work quickly and
reproducibly on SARS-CoV-2 proteins and also the mutants to come. Distributing
this work from the beginning was one of our most important priorities. In
addition to the protocols, we are also making the plasmids freely
available."
Dr Andreas Schlundt from the Institute for
Molecular Biosciences at Goethe University says: "With our work, we are
speeding up the global search for active agents: Scientific laboratories equipped
for this work do not have to first spend several months establishing and
optimising systems for the production and investigation of SARS-CoV-2 proteins,
but can now start their research work within two weeks thanks to our elaborated
protocols. Given the numerous mutations of SARS-CoV-2 to come, it is
particularly important to have access to reliable, rapid and well-established
methods for studying the virus in the laboratory. This will, for example, also
facilitate research on the so-called helper proteins of SARS-CoV-2, which have
remained under-investigated, but which also play a role in the occurrence of
mutations."
In the meantime, the work in the NMR
consortium continues: Currently, the researchers are working hard to find out
whether viral proteins can bind to potential drugs.
The research work was funded by the German
Research Foundation and the Goethe Coronavirus Fund. The high logistical effort
and constant communication of research results was supported by Signals, a
spin-off company of Goethe University.
Publication:
Nadide Altincekic, Sophie Marianne Korn,
Nusrat Shahin Qureshi, Marie Dujardin, Martí Ninot-Pedrosa
et. al. Large-scale recombinant
production of the SARS-CoV-2 proteome for high-throughput and structural
biology applications. Frontiers in Molecular Biosciences. https://doi.org/10.3389/fmolb.2021.653148
Additional
information: Folding of SARS-CoV2 genome reveals drug
targets – and preparation for “SARS-CoV3" https://tinygu.de/IcOo2
Images
may be downloaded here: www.uni-frankfurt.de/100668377
Caption:
Scientists Martin
Hengesbach (left) und Andreas Schlundt at the nuclear magnetic resonance (NMR)
spectrometre at Goethe-University Frankfurt, Germany. Photo: Uwe Dettmar for
Goethe-University Frankfurt, Germany
The
COVID-19 NMR Consortium:
https://covid19-nmr.de/
Scientific
contacts at Goethe University Frankfurt:
Dr Andreas Schlundt
Emmy Noether Junior Group Leader
Institute for Molecular Biosciences
Goethe University Frankfurt
Tel.: +49 69 798-29699
schlundt@bio.uni-frankfurt.de
Dr Martin Hengesbach
Junior Group Leader
Goethe University Frankfurt
Institute for Organic Chemistry and Chemical Biology
SFB 902 “Molecular Principles of RNA-based Regulation“
Tel.: +49 69 798-29130
hengesbach@nmr.uni-frankfurt.de
Partners:
Brazil
- National Center of Nuclear Magnetic Resonance (CNRMN, CENABIO), Federal University of Rio de Janeiro, Brazil
- Institute of Medical Biochemistry, Federal University of Rio de Janeiro, Brazil
- Multidisciplinary Center for Research in Biology (NUMPEX), Campus Duque de Caxias, Federal University of Rio de Janeiro, Duque de Caxias, Brazil
- Institute of Chemistry, Federal University of Rio de Janeiro, Brazil
- Multiuser Center for Biomolecular Innovation (CMIB), Department of Physics, São Paulo State University (UNESP), São José do Rio Preto, Brazil
- Laboratory of Toxicology, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil
France
- Molecular Microbiology and Structural Biochemistry (MMSB), UMR 5086, CNRS/Lyon University, France
- Université Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France
Germany
- Institute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Germany
- Center of Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt, Germany
- Institute for Molecular Biosciences, Goethe University Frankfurt, Germany
- Institute for Biochemistry, Goethe University Frankfurt, Germany
- Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Germany
- Institute of Biophysical Chemistry, Goethe University Frankfurt, Germany
- BMWZ and Institute of Organic Chemistry, Leibniz University Hannover, Germany
- Group of NMR-based Structural Chemistry, Helmholtz Centre for Infection Research, Braunschweig, Germany
- Structural Genomics Consortium, Buchmann Institute for Molecular Life Sciences (BMLS), Germany
- Signals GmbH & Co. KG, Frankfurt am Main, Germany
- Leibniz Institute on Aging – Fritz Lipmann Institute (FLI), Jena, Germany
- IBG-4, Karlsruhe Institute of Technology, Karlsruhe, Germany
- Department of Biology, Technical University of Darmstadt, Darmstadt, Germany
- Institute of Biochemistry and Biotechnology, Charles Tanford Protein Centre, Martin Luther University Halle-Wittenberg, Halle/Saale, Germany.
Greece
- Department of Pharmacy, University of Patras, Greece
Italy
- Structural Biology and Biophysics Unit, Fondazione Ri.MED, Palermo, Italy
- Magnetic Resonance Centre (CERM), University of Florence, Sesto Fiorentino, Italy
- Department of Chemistry “Ugo Schiff", University of Florence, Sesto Fiorentino, Italy
Latvia
- Latvian Biomedical Research and Study Centre, Riga, Latvia
- Latvian Institute of Organic Synthesis, Riga, Latvia
Switzerland
- Swiss Federal Institute of Technology, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland
Spain
- "Rocasolano" Institute for Physical Chemistry (IQFR), Spanish National Research Council (CSIC), Serrano, Spain
USA
- Institute for Molecular Virology, University of Wisconsin-Madison, WI, United States
- Department of Chemistry, University of California, Irvine, United States
- Laboratory of Chemical Physics, National Institute of Diabetes and Digestive Kidney Diseases, National Institute of Health, United States
- Department of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH, United States
- Department of Molecular Biology and Biochemistry, University of California, Irvine, California, United States
- Department of Molecular Biology and Biophysics, UC 72 onn Health, Farmington, CT, United States
Editor: Dr. Markus Bernards, Science Editor, PR & Communication Department, Tel: -49 (0) 69 798-12498, Fax: +49 (0) 69 798-763 12531, E-Mail: bernards@em.uni-frankfurt.de
Scientists at Goethe University Frankfurt and the Center for European Policies Studies develop a simple formula to estimate the necessary rate of vaccinations
The vaccination formula: rapid vaccination could avoid lockdown even with rising infection numbers
Despite rising infection numbers, contact restrictions could be avoided if the vaccination rate were fast enough. Professor Claudius Gros from Goethe University Frankfurt and Dr Daniel Gros from the Center for European Policies Studies in Brussels have developed a simple mathematical relation which allows to estimate the rate of vaccination necessary to maintain control of the pandemic without a lockdown and while avoiding overwhelming the health system and a spike in death rates. The study has been vetted and is forthcoming in Covid Economics.
FRANKFURT. As it has from the beginning, the pandemic continues to primarily affect older people. If the entire population of Germany became infected with SARS-CoV-2, statistically 1.5 million of those over 60 would die; among those under 60, the death toll would "only" be 75,000. This is why – in addition to certain particularly exposed population groups - vaccination strategies often prioritise the elderly with the aim of avoiding overburdening the health system with severe COVID-19 cases and high death rates. After all, vaccinating just a quarter of the population can prevent 95 percent of deaths.
Professor Claudius Gros from the Institute for Theoretical Physics at Goethe University Frankfurt and Dr Daniel Gros from the Center for European Policies Studies (CEPS) therefore focused on the older segment of the population when developing their vaccination formula. They show that COVID-19 fatalities are determined by three factors: The infection rate, the dependence of the risk on age, and the structure of the age pyramid. Germany, like almost all European countries, is particularly susceptible to the third wave: the average age of the population is high, the new mutant is highly infectious, but the vaccination rate is only slowly increasing. To keep the effects of the pandemic manageable, extensive contact restrictions are therefore necessary in order to keep infection rates low.
According to the two scientists, a rule of thumb can be used to determine the point at which it is possible to relax: They put the weekly increase in the number of infections in relation to the increase in vaccinations per week. Simplified, the relationship is as follows: If x percent more of the population falls ill per week, an additional x*f/100 percent of the population must be vaccinated in the same period. The factor f, which was f=2 at the beginning of the vaccination campaign, increases when part of the population has already been fully vaccinated. Currently we have f=6. This means that if the infection incidence increases by x=20 percent per week, 20*6/100=1.2% of the population would have to be additionally (fully) vaccinated. This applies to the vaccination doses administered by age. It should be taken into account that two vaccination doses are necessary for complete immunisation.
Dr Daniel Gros explains: "Given the low current vaccination rate, the 7-day incidence per week should not increase by more than 13 to 16 percent to prevent the health system from being overwhelmed. Over the past weeks, however, infection rates have increased by 25 percent, making extensive contact restrictions inevitable, otherwise aggressive mutants are likely to spread."
Prof. Claudius Gros says: "The relation we developed allows for a simple and quick estimate of how quickly we would need to vaccinate to keep the consequences of the pandemic for the health system manageable. Unfortunately, we have failed to incentivise pharmaceutical companies to rapidly scale up production, which is costly and resource-intensive, for example through higher prices for an earlier production of vaccine doses. Therefore, as we predicted in an earlier paper, companies have opted for a slow linear increase in production. From a business point of view, this is cost-effective, but it results in us not having sufficient amounts of vaccine available fast enough."
Publication: Claudius Gros and Daniel Gros, „How fast must vaccination campaigns proceed in order to beat rising Covid-19 infection numbers?“ in: Covid Economics (in press), https://arxiv.org/abs/2103.15544
Further information: Professor Claudius Gros Institute for Theoretical Physics Goethe University Frankfurt gros07@itp.uni-frankfurt.de
Editor: Dr. Markus Bernards, Science Editor, PR & Communication Department, Tel: -49 (0) 69 798-12498, Fax: +49 (0) 69 798-763 12531, bernards@em.uni-frankfurt.de
Contributions from more than 2000 large and small donors make numerous research projects at Goethe University and Frankfurt University Hospital on overcoming the pandemic
Goethe Coronavirus Fund reaches 5 million euro mark
A short ten months after Goethe University and
Frankfurt University Hospital first called for donations, the Goethe Coronavirus
Fund has passed the targeted 5 million euro mark. The idea of the Goethe Coronavirus
Fund came about in the first days of the pandemic: researchers require
immediate and unbureaucratic support in order to make their contribution to
overcoming the coronavirus crisis. More than 2000 private individuals,
foundations and companies have meanwhile supported the goal of joining forces
and providing competent help.
FRANKFURT. “Making
a donation to research helped me overcome a feeling of helplessness during the
first days of the coronavirus crisis,” says Raina Jockers, one of the more than
2000 donors for the Goethe Coronavirus Fund, explaining her motivation. The
feelings of the Goethe University graduate are undoubtedly shared by many. The
majority of donors contributed between 10 and 100 euros to the fund. The
smallest donation came from the donation of bonus points from the “payback” programme
and amounted to 2 cents; the largest was almost one million euros. Eight donors
gave sums of more than 100,000 euros.
Using the non-profit online fundraising
platform betterplace.org for the
first time, the university’s call for donations reached even beyond Frankfurt
citizens and foundations and companies from the Rhine-Main area, with donations
coming in from Hamburg, Munich and even the USA. The fundraising platform also
reported regularly on the work of the scientists, which may have motivated some
donors to stick with it: one anonymous donor contributed 20 euros to the fund
every month.
“In the pandemic, we wanted to help with
what we do best: with our research,” says Professor Manfred Schubert-Zsilavecz,
Goethe University Vice President. “So we simply jumped in at the deep end with
our fundraising campaign and set ourselves an ambitious target: 5 million euros
in donations. The fact that we have reached the 5 million euro mark in less than
a year after our first call for donations makes us deeply grateful. Many
private donors, as well as foundations and companies have been extremely
generous. They funded research that helps us all, keeping others in mind during this pandemic. This
should really encourage us for the long road ahead.”
The Goethe Coronavirus Fund provided researchers at Goethe
University and Frankfurt University Hospital with start-up support. Many of
them have in the meantime raised additional funds for research having to do
with SARS-CoV-2. The virologist Professor Sandra Ciesek and the infectologist
Professor Maria Vehreschild, for example, are today part of the EU-funded CARE
Consortium. Sandra Ciesek’s successes in drug research have made her one of the
most prominent coronavirus researchers in Germany. Maria Vehreschild was one of
the first to systematically collect clinical data and samples from COVID-19
patients and supplied her samples to vaccine and drug researchers throughout
Germany; in the meantime, her database has been merged into a Germany-wide
biobank.
But researchers from the social sciences
and humanities have also profited from the Goethe Coronavirus Fund. More than
40 projects are now being funded – including the coronavirus crisis hotline,
and studies by psychologist Professor Ulrich Stagnier on the psychological consequences
of the pandemic.
The latest project supported by the
Coronavirus Fund is dedicated to the work situation of healthcare workers and
doctors in COVID-19 care in Hessian hospitals who are under particular strain.
The cooperation project of the University Hospital Frankfurt and the Protestant
University of Applied Sciences in Darmstadt first examines the effects on the
employees. The results will be used to make recommendations for managers and healthcare
workers, as well as concrete options for workplace health promotion. The
evaluation of the first sub-study of the project is currently underway.
Further
donations possible at: https://www.goethe-corona-fonds.betterplace.org and
through
the donation account: Landesbank Hessen-Thüringen
IBAN: DE95 5005 0000
0001 0064 10
Reason
for payment: Goethe-Corona-Fonds
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