Proteomics is a powerful method for evaluating drug-protein interactions. It is based on evaluating the quantity of thousands of cellular proteins that are produced upon treatment with chemicals.
We can process cell pellets or lysates of cells treated with varying chemicals or concentrations of chemicals.
Technical Specifications
Sample processing:
- From protein extraction to peptide quantification
- TMT-labelling and clean-ups
- Fractionation
- LC-MS3 analysis on mass spectrometer
- Raw file processing for quality control and primary data output
Instrumentation:
- ThermoFisher QExactive HF with EASY 1200
- ThermoFisher Fusion Lumos with EASY 1200
- ThermoFisher Ascend with Vanquish Neo
Responsible: Prof.Christian Münch