Prof. Dr. Jennifer Dressman
Research focus
Prof. Dressman’s research focuses on predicting the in vivo performance of drugs and dosage forms after oral administration. She is best known for pioneering the use of Biorelevant dissolution testing and has made significant contributions to combining dissolution testing with physiologically based pharmacokinetic modelling to achieve quantitative predictions of oral absorption.
Professor Dressman is a Fellow of AAPS, CRS, FIP and APSTJ. Her awards include the Ebert Prize 1986, Phoenix Prize 2003, Distinguished Scientist Award (FIP 2008), Best Paper Award EJBP 2010, Highly Cited Researcher (2016), International Woman Pharmaceutical Scientist of the Year APSTJ 2017 and Most Informative Research Paper Simcyp 2017.
Publications
Top Ten cited papers
C Leuner, JB Dressman
Improving drug solubility for oral drug delivery using solid molecular dispersions.
Invited review, 50th Anniversary edition
Eur. J. Pharm. Biopharm. 50:47-60 (2000)
JB Dressman, GL Amidon, C Reppas, VP Shah
Dissolution testing as a prognostic tool for oral drug absorption: immediate release dosage forms
Pharm. Res. 15: 11-22 (1998)
E Galia, E Nicolaides, D Hörter, R Löbenberg, C Reppas, JB Dressman
Evaluation of various dissolution media for predicting in vivo performance of Class I and II drugs.
Pharm. Res. 15: 698-705 (1998)
M Lindenberg, J Dressman, S Kopp
Classification of orally administered drugs on the WHO „Essential Medicines“ List according to the BCS.
Eur. J. Pharm. Biopharm. 58:265-278 (2004)
D Hörter and JB Dressman
Influence of physicochemical properties on drug dissolution in the GI tract
Advanced Drug Delivery Reviews 25:3-14 (1997)
WNA Charman, CJH Porter, SD Mithani, JB Dressman
Physicochemical and physiological mechanisms for the effects of food on drug absorption: the role of lipids and pH
J. Pharm. Sci. 86:269-282 (1997)
JB Dressman, RR Berardi, LC Dermentzoglou, TL Russell, SP Schmaltz,
JL Barnett, K Jarvenpaa
Upper gastrointestinal pH in young, healthy men and women.
Pharm. Res. 7:756-761 (1990)
JB Dressman, C Reppas
In vitro-in vivo correlations for lipophilic, poorly water-soluble drugs.
Europ. J. Pharm. Sci. 11(Supp 2): S73-S80 (2000)
E Jantratid, N Janßen, C Reppas, J Dressman
Dissolution media simulating conditions in the proximal human gastrointestinal tract: an update
Pharm. Res. (2008) 25:1663-1676
L Kalantzi, K Goumas, V Kalioras, B Abrahamsson, J Dressman, C Reppas
Characterization of the human upper gastrointestinal contents under conditions simulating bioavailability/bioequivalence studies.
Pharm. Res. 23:165-176 (2006)