Ort / Place
Physik Campus Riedberg, Max-von-Laue-Str. 1, 60438 Frankfurt
Großer Hörsaal, Raum 0.111

Zeit / Time
Mittwochs / Wednesday , 16.00 Uhr c.t.



Dr. Stefan Gillessen
Max-Planck-Institut für extraterrestrische Physik, Garching

The Galactic Center: A unique astrophysical laboratory


Prof. Werner Maurer Zürcher
Hochschule Winterthur, Schweiz

Physik der dynamischen Systeme (Systemphysik)


Dr. Hendrik van Hees
Institut für Theoretische Physik, Goethe-Universität Frankfurt

Dileptons and photons Messengers from strongly interacting matter under extreme conditions from the hot and dense state


Prof. Dr. Andrea Markelz
Department of Physics, University at Buffalo, SUNY, Buffalo,  USA
Adjunct Professor, Department of Structural Biology, University at Buffalo, SUNY, Buffalo, USA
Visiting Professor, Department of Physics, Univeristat, Regensburg, Germany

Terahertz Light Fingerprints Biomolecular Dynamics


Prof. Dr. Vladimir Falko
National Graphene Institute University of Manchester Manchester, UK

Moiré superlattices and magnetic minibands in graphene heterostructures


Prof. Dr. Klaus Blaum
Max-Planck-Institut für Kernphysik Heidelberg

Precision Experiments with Stored and Cooled Ions


Dr. Nadine Schwierz-Neumann
Emmy Noether Nachwuchsgruppenleiterin Max-Planck-Institut für Biophysik Frankfurt

Metal cations and RNA - a highly charged problem with a dynamic future


Prof. Dr. Hartmut Wittig              
Institut für Kernphysik, Johannes Gutenberg-Universität Mainz

The limits of the Standard Model and the role of Lattice QCD


Prof. Dr. Werner Mäntele
Institut für Biophysik, Goethe-Universität Frankfurt
-A b s c h i e d s v o r l e s u n g-
Bioanalytical Infrared Spectroscopy: Quo vadis ?

Infrared (IR) spectroscopy has long been established as a routine analytical technique in chemistry, but applications for biological samples seemed impossible due to instrumental limitations such as low emissivity of thermal sources and long recording times. In addition, water as a strong absorber prevented “real” biological samples from being analysed. The introduction of Fourier transform IR (FT-IR) techniques in the 80’s marks the first milestone for bioanalytical IR spectroscopy, and new techniques for the preparation of biological samples led to a rapidly growing field. FT-IR techniques are since used, as reaction-modulated difference techniques, for the analysis of biopolymers, complemented by ultrafast laser techniques. Our community has since then learnt to track and analyse individual bonds in macromolecules, their dynamics and their reactivity, from picoseconds to seconds or minutes. IR spectroscopy is now an established technique complementing structure analysis e.g. by X-ray crystallography or 2-D-NMR spectroscopy.
The advent of quantum cascade lasers (QCL) in the late nineties, powerful narrow-band single wavelength IR emitters, multi-wavelength sources, or, with an external cavity (EC), tunable EC-QCLs presents a further milestone in bioanalytical IR spectroscopy. Their power reaches to hundreds of mW and their tunability can extend over several 100 cm-1, sufficiently broad to scan the entire IR fingerprint region within some msec. This opened IR spectroscopy for biomedical applications ex vivo and in vivo, for sensors and mobile devices.
The lecture presents bioanalytical and biomedical applications of IR technology at some typical examples. We will start from earlier work on the structure, function and dynamics of proteins an move to most recent developments for the analysis of body fluids in vitro and skin parameters in vivo.


Prof. Dr. Joachim Frank
Frank Lab Columbia University New York, USA

The future of cryo-EM

Now that close-to-atomic resolution can be reached almost routinely in many cases, single-particle cryo-EM is about to fill a large gap in the structural database, and this will have a significant impact on the war chest of Molecular Medicine. In terms of future developments I'd like to single out two promising directions:  time-resolved cryo-EM (the ability to image short-lived states), and mapping of a continuum of states of a molecule (especially molecular machines) in a system in equilibrium. 

Rückblick Physikalisches Kolloquium:
SS 2010, WS 2010/11, SS 2011, WS 2011/12, SS 2012, WS 2012/13, SS 2013, WS 2013/14, SS 2014, WS2014/15, SS2015, WS2015/16, SS2016, WS2016/17, SS 2017, WS 2017/18