Original- und Übersichtsarbeiten 2005-1998

Anatomie III


Fricke K, Schulz A, John H, Forssmann WG, Maronde E (2005) Isolation and characterisation of a novel POMC-derived peptide from hemofiltrate of chronic renal failure patients. Endocrinology 146: 2060-2068

Fung C, Schleicher A, Kowalski T, Oelschläger HA (2005 Sep) Mapping auditory cortex in the La Plata dolphin (Pontoporia blainvillei). Brain Res Bull 66: 353-356

Von Gall C, Weaver DR, Moek J, Jilg A, Stehle JH, Korf HW (2005) Melatonin plays a crucial role in the regulation of rhythmic clock gene expression in the mouse pars tuberalis. Ann N Y Acad Sci 1040: 508-511

Jilg A, Moek J, Weaver DR, Korf HW, Stehle JH, von Gall C (2005) Rhythms in clock proteins in the mouse pars tuberalis depend on MT1 melatonin receptor signalling. Eur J Neurosci 22: 2845-2854

Kahles T, Foerch C, Sitzer M, Schroeter M, Steinmetz H, Rami A, Neumann-Haefelin T (2005)Tissue plasminogen activator mediated blood-brain barrier damage in transient focal cerebral ischemia in rats: relevance of interactions between thrombotic material and thrombolytic agent.Vascul Pharmacol 43: 254-259

Karolczak M, Korf HW, Stehle JH (2005) The rhythm and blues of gene expression in the rodent pineal gland. Endocrine 27: 89-100

Kell CA, Stehle JH (2005) Just the two of us: melatonin and adenosine in rodent pituitary function. Ann Med 37:105-120

Konig HG, Kogel D, Rami A, Prehn JH (2005) TGF-{beta}1 activates two distinct type I receptors in neurons: implications for neuronal NF-{kappa}B signaling. J Cell Biol 168:1077-1086

Kutzleb C, Busmann A, Wendland M, Maronde E (2005) Discovery of Novel Regulatory Peptides by Reverse Pharmacology: Spotlight on Chemerin and the RF-amide Peptides Metastin and QRFP. In: Exploiting the Peptide Pool: New Structures, Novel Functions and Therapeutic Opportunities Guest Editor: Knut Adermann. Current Protein and Peptide Science 6: 265-278

Mitrovic V, Lüss H, Nitsche K, Forssmann K, Fricke K, Maronde E, Forssmann WG,  Meyer M (2005) Effects of the Renal Natriuretic Peptide Urodilatin (INN: Ularitide) in Patients with Decompensated Chronic Heart Failure A Double-Blind, Placebo-Controlled, Ascending Dose Trial. American Heart Journal, accepted for publication AHJ40877R1

Nemec P, Burda H, Oelschläger HA (2005 Apr) Towards the neural basis of magnetoreception: a neuroanatomical approach. Naturwissenschaften 92: 151-157

Poth C, Fung C, Gunturkun O, Ridgway SH, Oelschläger HA (2005 Sep) Neuron numbers in sensory cortices of five delphinids compared to a physeterid, the pygmy sperm whale. Brain Res Bull 66: 357-260

Siegelin M, Touzani O, Toutain J, Liston P, Rami A (2005) Induction and redistribution of XAF1, a new antagonist of XIAP in the rat brain after transient focal ischemia. Neurobiol Dis 20: 509-518

Siegelin MD, Kossatz LS, Winckler J, Rami A (2005) Regulation of XIAP and Smac/DIABLO in the rat hippocampus following transient forebrain ischemia. Neurochem Int 46: 41-51

Thees S, Hubbard GB, Winckler J, Schultz C, Rami A (2005) Specific alteration of the Bax/Bcl2 ratio and cytochrome c without execution of apoptosis in the hippocampus of aged baboons. Restor Neurol Neurosci 23: 1-9

Zekri L, Chebli K, Tourriere H, Nielsen FC, Hansen TV, Rami A, Tazi J (2005) Control of fetal growth and neonatal survival by the RasGAP-associated endoribonuclease G3BP. Mol Cell Biol 25: 8703-8716


Fricke K, Heitland A, Maronde E (2004)  Cooperative activation of lipolysis by protein kinase A and protein kinase C pathways in 3T3-L1 adipocytes. Endocrinology 145: 4940-4947

Karolczak M, Burbach GJ, Sties G, Korf HW, Stehle JH (2004) Clock gene mRNA and protein rhythms in the pineal gland of mice. Eur J Neurosci 19: 3382-3388

Kell CA, Dehghani F, Wicht H, Molina CA, Korf HW, Stehle JH (2004) Distribution of transcription factor inducible cyclicAMP early repressor (ICER) in rodent brain and pituitary. J Comp Neurol 478: 379-394


Jin X, von Gall C, Pieschl RL, Gribkoff VK, Stehle JH, Reppert SM, Weaver DR (2003) Targeted disruption of the mouse Mel(1b) melatonin receptor. Mol Cell Biol 23: 1054-1060

Koch M, Mauhin V, Stehle JH, Schomerus C, Korf HW (2003) Dephosphorylation of pCREB by protein serine/threonine phosphatases is involved in inactivation of Aanat gene transcription in rat pineal gland. J Neurochem 85: 170-179

Korf HW, von Gall C, Stehle J (2003) The circadian system and melatonin: lessons from rats and mice. Chronobiol Int 20: 697-710

Krause A, Sillard R, Kleemeier B, Klüver E, Maronde E, Conejo-García JR, Forssmann WG, Schulz-Knappe P, Nehls MC, Wattler F, Wattler S, Adermann K (2003) Isolation and biochemical characterisation of LEAP-2, a novel blood peptide expressed in the liver. Protein Science 12: 143-152

Lammerich HP, Busmann A, Kutzleb C, Wendland M, Seiler P, Meyer U, Meyer M, Forssmann WG, Maronde (2003) Hemorphins VV-H-7 and LVV-H-7 activate the orphan bombesin type 3 receptor. British Journal of Pharmacology 138: 1431-1440

Maronde E, Motzkus D (2003) Oscillation of human period 1 (hPER1) reporter gene activity in human neuroblastoma cells in vivo. Chronobiol Int 20: 671-681

Rami A, Volkmann T, Agarwal R, Schoninger S, Nurnberger F, Saido TC, Winckler J (2003) beta2-Adrenergic receptor responsiveness of the calpain-calpastatin system and attenuation of neuronal death in rat hippocampus after transient global ischemia. Neurosci Res 47: 373-82

Rami A (2003) Ischemic neuronal death in the rat hippocampus: the calpain-calpastatin-caspase hypothesis. Neurobiol Dis 13: 75-88

Rami A, Jansen S, Giesser I, Winckler J (2003) Post-ischemic activation of caspase-3 in the rat hippocampus: evidence of an axonal and dendritic localisation. Neurochem Int 43: 211-223

Rami A, Sims J, Botez G, Winckler J (2003) Spatial resolution of phospholipid scramblase 1 (PLSCR1), caspase-3 activation and DNA-fragmentation in the human hippocampus after cerebral ischemia. Neurochem Int 43: 79-87

Reimertz C, Kogel D, Rami A, Chittenden T, Prehn JH (2003) Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. J Cell Biol 162: 587-597

Sedmera D, Misek I, Klima M, Thompson RP (2003 Aug) Heart development in the spotted dolphin (Stenella attenuata). Anat Rec A Discov Mol Cell Evol Biol 273: 687-699

Stehle JH, von Gall C, Korf HW (2003) Melatonin: a clock-output, a clock-input. J Neuroendocrinol 15: 383-389


Bisler S, Schleicher A, Gass P, Stehle JH, Zilles K, Staiger JF (2002) Expression of c-Fos, ICER, Krox-24 and JunB in the whisker-to-barrel pathway of rats: time course of induction upon whisker stimulation by tactile exploration of an enriched environment. J Chem Neuroanat 23: 187-98

Von Gall C, Garabette ML, Kell CA, Frenzel S, Dehghani F, Schumm-Draeger PM, Weaver DR, Korf HW, Hastings MH, Stehle JH (2002) Rhythmic gene expression in pituitary depends on heterologous sensitization by the neurohormone melatonin. Nat Neurosci 5: 234-8

Von Gall C, Stehle JH, Weaver DR 2002 Mammalian melatonin receptors: molecular biology and signal transduction. Cell Tissue Res 309: 151-162

Korf HW, Stehle JH (2002) The circadian system: circuits-cells-clock genes. Cell Tissue Res 309: 1-2

Motzkus D, Albrecht U, Maronde E (2002) The human Per1 gene is inducible by interleukin-6. J Mol Neurosci 18: 105-109

Oster H, Maronde E, Albrecht U (2002) The Circadian Clock as a Molecular Calendar. Chronobiol Int 19: 507-516

Revermann M, Maronde E, Ruth P, Korf HW (2002) Protein kinase G Type I is colocalized with Arginine-Vasopressin in the Rat Suprachiasmatic Nucleus. Neuroscience Letters 334: 119-122

Richardson MK, Oelschläger HA (2002) Time, pattern, and heterochrony: a study of hyperphalangy in the dolphin embryo flipper. Evol Dev 4: 435-444

Schöniger S, Maronde E, Kopp MDA, Korf HW, Nürnberger F (2002) The transcription factor CREB and its stimulus-dependent phosphorylation in the bovine subcommissural organ, Cell Tissue Res 308: 131-142

Schöniger S, Kopp MDA, Schomerus C, Maronde E, Dehghani F, Meiniel A, Rodríguez EM, Korf HW, Nürnberger F (2002) Effects of neuroactive substances on the activity of subcommissural organ cells in dispersed cell and explant cultures. Cell Tissue Res 307: 101-114

Stehle JH, von Gall C, Korf HW (2002) Organisation of the circadian system in melatonin-proficient C3H and melatonin-deficient C57BL mice: a comparative investigation. Cell Tissue Res 309(1):173-82. Epub 2002 May 25. Review.


Botez G, Rami A (2001) Immunoreactivity for Bcl-2 and C-Jun/AP1 in hippocampal corpora amylacea after ischaemia in humans. Neuropathol Appl Neurobiol 27: 474-480

Von Gall C, Schneider-Huther I, Pfeffer M, Dehghani F, Korf HW, Stehle JH (2001) Clock gene protein mPER1 is rhythmically synthesized and under cAMP control in the mouse pineal organ. J Neuroendocrinol 13: 313-316

Hirsch J, Kruhoffer M, Plenz G, Adermann K, Heitland A, Maronde E, Meyer M, Forssmann WG, Herter P, Plenz G, Schlatter E (2001) Cellular localization, membrane distribution, and possible function of guanylate cyclases A and 1 in collecting ducts of rat. Cardiovascular Res 51: 553-561

Kinkel MD, Thewissen JG, Oelschläger HA (2001) Rotation of middle ear ossicles during cetacean development. J Morphol 249: 126-131

Krause A, Liepke C, Meyer M, Ackermann K, Forssmann WG, Maronde E (2001) Human natriuretic peptides exhibit antimicrobial activity. Eur J Med Res: 215-218

Maronde E, Korf HW, Niemann P, Genieser HG (2001) Direct comparison of the potency of three novel cAMP analogs to induce CREB-phosphorylation in rat pinealocytes. J Pineal Res 31: 183-185

Nemec P, Altmann J, Marhold S, Burda H, Oelschläger HA (2001) Neuroanatomy of magnetoreception: the superior colliculus involved in magnetic orientation in a mammal. Science 294(5541): 366-368

Rami A, Volkmann T, Winckler J (2001) Effective reduction of neuronal death by inhibiting gap junctional intercellular communication in a rodent model of global transient cerebral ischemia. Exp Neurol 170(2):297-304

Stehle JH, von Gall C, Schomerus C, Korf HW (2001) Of rodents and ungulates and melatonin: creating a uniform code for darkness by different signaling mechanisms. J Biol Rhythms 16: 312-325

Stehle JH, von Gall C, Korf HW (2001) Analysis of cell signalling in the rodent pineal gland deciphers regulators of dynamic transcription in neural/endocrine cells. Eur J Neurosci 14: 1-9


Dehghani F, Maronde E, Schachmayer W, Korf HW (2000) Expression of neurofilament and its prognostic value in oligodendrogliomas. Acta Neuropathologia 100: 122-130

Von Gall C, Weaver DR, Kock M, Korf HW, Stehle JH (2000) Melatonin limits transcriptional impact of phosphoCREB in the mouse SCN via the Mel1a receptor. Neuroreport 11: 1803-1807

Von Gall C, Lewy A, Schomerus C, Vivien-Roels B, Pevet P, Korf HW, Stehle JH (2000) Transcription factor dynamics and neuroendocrine signalling in the mouse pineal gland: a comparative analysis of melatonin-deficient C57BL mice and melatonin-proficient C3H mice. Eur J Neurosci 12: 964-972

Kroeber S, Meissl H, Maronde E, Korf HW (2000) Analysis of signal transduction cascades reveal an essential role of calcium ions for the regulation of melatonin biosynthesis in the light sensitve pineal organ of the rainbow trout (Oncorhyncus mykiss). J Neurochem 74: 2478-2489

Kulaksiz H, Arnold R, Göke B, Maronde E, Meyer M, Fahrenholz F, Forssmann WG, Eissele R (2000) Expression and cell-specific localization of the cholecystokinin B/gastrin receptor in the human stomach. Cell Tiss Res 299: 289-298

Motzkus D, Maronde E, Grunenberg U, Lee CC, Forssmann WG, Albrecht U (2000) The human PER1 gene is transcriptionally regulated by multiple signaling pathways. FEBS Lett 486: 315-319

Oelschläger HA, Nakamura M, Herzog M, Burda H (2000) Visual system labeled by c-Fos immunohistochemistry after light exposure in the 'blind' subterranean zambian mole-rat (Cryptomys anselli). Brain Behav Evol 55: 209-220

Pfeffer M, Maronde E, Korf HW, Stehle JH (2000) Antisense experiments reveal molecular details on mechanisms of ICER suppressing cAMP-inducible genes in rat pinealocytes. J Pineal Res 29: 24-34

Rami A, Agarwal R, Botez G, Winckler J (2000) mu-Calpain activation, DNA fragmentation, and synergistic effects of caspase and calpain inhibitors in protecting hippocampal neurons from ischemic damage. Brain Res 866: 299-312

Schwede F, Maronde E, Genieser HG, Jastorff B (2000) Cyclic nucleotide analogs as biochemical tools and prospective drugs. Pharmacology and Therapeutics 87: 199-226

Staiger JF, Bisler S, Schleicher A, Gass P, Stehle JH, Zilles K (2000) Exploration of a novel environment leads to the expression of inducible transcription factors in barrel-related columns. Neuroscience 99: 7-16

Sterba O, Klima M, Schildger B (2000) Embryology of dolphins. Staging and ageing of embryos and fetuses of some cetaceans. Adv Anat Embryol Cell Biol 157: III-X, 1-133

Zhu Y, Roth-Eichhorn S, Braun N, Culmsee C, Rami A, Krieglstein J (2000) The expression of transforming growth factor-beta1 (TGF-beta1) in hippocampal neurons: a temporary upregulated protein level after transient forebrain ischemia in the rat. Brain Res 866: 286-298


Klima M (1999) Development of the cetacean nasal skull. Adv Anat Embryol Cell Biol 149: 1-143

Lindenlaub T, Oelschläger HA (1999) Morphological, morphometric, and functional differences in the vestibular organ of different breeds of the rat (Rattus norvegicus). Anat Rec 255: 15-9

Maronde E, Pfeffer M, von Gall C, Dehghani F, Schomerus C, Wicht H, Kroeber S, Olcese J, Stehle JH, Korf HW (1999) Signal transduction in the rodent pineal organ. From the membrane to the nucleus. Adv Exp Med Biol 460: 109-131

Maronde E, Pfeffer M, Olcese J, Molina CA, Schlotter F, Dehghani F, Korf HW, Stehle JH (1999) Transcription factors in neuroendocrine regulation: rhythmic changes in pCREB and ICER levels frame melatonin synthesis. J Neurosci 19: 3326-3336

Maronde E, Wicht H, Tasken K, Olcese JM, Korf HW (1999) Melatonin biosynthesis in the rat pineal gland is regulated via cAMP-dependent protein kinase type II and phosphorylation of the transcription cAMP-regulated element binding protein. J Pineal Res 27: 170-182

Pfeffer M, Maronde E, Molina CA, Korf HW, Stehle JH (1999) Inducible cyclic AMP early repressor protein in rat pinealocytes: a highly sensitive natural reporter for regulated gene transcription. Mol Pharmacol 56: 279-89

Pfeffer M, Maronde E, Olcese JM, Korf HW, Stehle JH (1999) The transcription factor ICER is a natural reporter for cAMP-gated signal transduction pathways. Mol Pharmacol 56: 279-289

Maronde E, Pfeffer M, von Gall C, Dehghani F, Schomerus C, Kroeber S, Olcese J, Stehle J, Korf HW (1999) Adv Exp Med Biol 460: 109-131

Wicht H, Maronde E, Olcese JM, Korf HW (1999) The recording of dose-response curves in immunocytochemical preparations by semi-quantitative image analysis. Histochem Cytochem 47: 411-419


Von Gall C, Duffield GE, Hastings MH, Kopp MD, Dehghani F, Korf HW, Stehle JH (1998) CREB in the mouse SCN: a molecular interface coding the phase-adjusting stimuli light, glutamate, PACAP, and melatonin for clockwork access. J Neurosci 18: 10389-10397

Jastrow H, Burda H, Oelschläger HA (1998) Unilateral absence of the terminal nerve and distribution of gonadotropin-releasing hormone immunoreactive neurons in the brain of the common mole-rat (Cryptomys, Rodentia). Brain Res 813: 229-40

Korf HW, Schomerus C, Stehle JH (1998) The pineal organ, its hormone melatonin, and the photoneuroendocrine system. Adv Anat Embryol Cell Biol 146:1-100. Review

Oelschläger HA, Kemp B (1998) Ontogenesis of the sperm whale brain. J Comp Neurol 399: 210-228

Oelschläger HA, Helpert C, Northcutt RG (1998) Coexistence of FMRFAMIDE-like and LHRH-like immunoreactivity in the terminal nerve and forebrain of the big brown bat, Eptesicus fuscus. Brain Behav Evol 52: 139-147

Pfeffer M, Kuhn R, Krug L, Korf HW, Stehle JH (1998) Rhythmic variation in beta1-adrenergic receptor mRNA levels in the rat pineal gland: circadian and developmental regulation. Eur J Neurosci 10: 2896-28904

Pfeffer M, Stehle JH (1998) Ontogeny of a diurnal rhythm in arylalkylamine-N-acetyltransferase mRNA in rat pineal gland. Neurosci Lett 248: 163-166

Rami A, Krieglstein J (1998) Muscarinic-receptor antagonist scopolamine rescues hippocampal neurons from death induced by glutamate. Brain Res 788: 323-326

Rami A, Rabie A, Winckler J (1998) Synergy between chronic corticosterone treatment and cerebral ischemia in producing damage in noncalbindinergic neurons. Exp Neurol 149: 439-446