Original- und Übersichtsarbeiten 2006-2010

Anatomie II


Christ E, Pfeffer M, Korf HW, von Gall C (2010) Pineal melatonin synthesis is altered in Period1 deficient mice. Neuroscience, 171: 398-406

Baudrexel S, Nürnberger L, Rüb U, Seifried C, Klein JC, Deller T, Steinmetz H, Deichmann R, Hilker R (2010) Quantitative mapping of T1 and T2* discloses nigral and brainstem pathology in early Parkinson's disease. Neuroimage, 51: 512-520

Dehghani F, Sayan M, Conrad A, Evers J, Ghadban C, Blaheta R, Korf HW, Hailer NP (2010) Inhibition of microglial and astrocytic inflammatory responses by the immunosuppressant mycophenolate mofetil. Neuropath Appl Neuro, 36: 598-611

Ebrahimi F, Hezel M, Koch M, Ghadban C, Korf HW, Dehghani F (2010) Analyses of neuronal damage in excitotoxically lesioned organotypic hippocampal slice cultures. Ann Anat, 192: 199-204

Elden AC, Kim HJ, Hart MP, Chen-Plotkin AS, Johnson BS, Fang X, Armakola M, Geser F, Greene R, Lu MM, Padmanabhan A, Clay-Falcone D, McCluskey L, Elman L, Juhr D, Gruber PJ, Rüb U, Auburger G, Trojanowski JQ, Lee VM, Van Deerlin VM, Bonini NM, Gitler AD (2010) Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS. Nature, 466: 1069-1075

Ghebremedhin E, Rosenberger A, Rüb U, Vuksic M, Berhe T, Bickeböller H, de Vos RA, Thal DR, Deller T (2010) Inverse relationship between cerebrovascular lesions and severity of lewy body pathology in patients with lewy body diseases. J Neuropathol Exp Neurol 69: 442-448

Grinberg LT, Rüb U, Alho AT, Heinsen H (2010) Brainstem pathology and non-motor symptoms in PD. J Neurol Sci, 289: 81-88

Parlapani E, Schmitt A, Wirths O, Bauer M, Sommer C, Rüb U, Skowronek MH, Treutlein J, Petroianu GA, Rietschel M, Falkai P (2010) Gene expression of neuregulin-1 isoforms in different brain regions of elderly schizophrenia patients. World J Biol Psychiatry, 11:243-250

Pfeffer M, Plenzig S, Gispert S, Wada K, Korf HW, Von Gall C (2010) Disturbed sleep/wake rhythms and neuronal cell loss in lateral hypothalamus and retina of mice with a spontaneous deletion in the ubiquitin carboxyl-terminal hydrolase L1 gene. Neurobiol Aging, Apr 1

Seidel K, den Dunnen WF, Schultz C, Paulson H, Frank S, de Vos RA, Brunt ER, Deller T, Kampinga HH, Rüb U (2010) Axonal inclusions in spinocerebellar ataxia type 3. Acta Neuropathol 120:449-460

Seidel K, Schöls L, Nuber S, Petrasch-Parwez E, Gierga K, Wszolek Z, Dickson D, Gai WP, Bornemann A, Riess O, Rami A, den Dunnen WF, Deller T, Rüb U, Krüger R (2010) First appraisal of brain pathology owing to A30P mutant alpha-synuclein. Ann Neurol 67:684-689

Thomann KD, Schomerus C, Sebestény T, Rauschmann M (2010) ["Isolated injury" of the alar ligaments: MRI diagnosis and surgical therapy]. Orthopade, 39: 285-298

Unfried C, Burbach G, Korf HW, von Gall C J (2010) Melatonin receptor 1-dependent gene expression in the mouse pars tuberalis as revealed by cDNA microarray analysis and in situ hybridization. J Pineal Res, 48: 148-156

Wicht H, Laedtke E, Korf HW, Schomerus C (2010) Spatial and temporal expression patterns of Bmal delineate a circadian clock in the nervous system of Branchiostoma lanceolatum. J Comp Neurol, 518: 1837-1846

Yasuo S, Koch M, Schmidt H, Ziebell S, Bojunga J, Geisslinger G, Korf HW (2010) An endocannabinoid system is localized to the hypophysial pars tuberalis of Syrian hamsters and responds to photoperiodic changes. Cell Tissue Res, 340: 127-136

Yasuo S, Unfried C, Kettner M, Geisslinger G, Korf HW (2010) Localization of an endocannabinoid system in the hypophysial pars tuberalis and pars distalis of man. Cell Tissue Res, 342: 273-281

Yasuo S, Yoshimura T, Ebihara S, Korf HW (2010) Photoperiodic control of TSH-beta expression in the mammalian pars tuberalis has different impacts on the induction and suppression of the hypothalamo-hypopysial gonadal axis. J Neuroendocrinol 22: 43-50


Ansari N, Agathagelidis M, Lee C, Korf HW, von Gall C (2009) Differential maturation of circadian rhythms in clock gene proteins in the suprachiasmatic nucleus and the pars tuberalis during mouse ontogeny. Eur J Neurosci, 29: 477-489

Kreutz S, Koch M, Böttger C, Ghadban C, Korf HW, Dehghani F (2009) 2-Arachidonoylglycerol elicits neuroprotective effects on excitotoxically lesioned dentate gyrus granule cells via abnormal-cannabidiol-sensitive receptors on microglial cells. Glia 57: 286-294

Pfeffer M, Müller CM, Mordel J, Meissl H, Ansari N, Deller T, Korf HW, von Gall C (2009) The mammalian molecular clockwork controls rhythmic expression of its own input pathway components. J Neurosci, 29: 6114-6123

Stavridis SI, Dehghani F, Korf HW, Hailer NP (2009) Cocultures of rat sensorimotor cortex and spinal cord slices to investigate corticospinal tract sprouting. Spine, 34: 2494-2499

Unfried C, Ansari N, Yasuo S, Korf HW, von Gall C (2009) Impact of melatonin and molecular clockwork components on the expression of thyrotropin beta-chain (Tshb) and the Tsh receptor in the mouse pars tuberalis. Endocrinology, 150: 4653-4662

Yasuo S, Yoshimura T, Ebihara S, Korf HW (2009) Melatonin transmits photoperiodic signals through the MT1 melatonin receptor. J Neurosci, 29: 2885-2889


Foerch C, Korf HW, Steinmetz H, Sitzer M (2008) Abrupt shift of the pattern of diurnal variation in stroke onset with daylight saving time transitions. Circulation 118: 284-290

Von Gall C, Weaver DR (2008) Loss of responsiveness to melatonin in the aging mouse suprachiasmatic nucleus. Neurobiol Aging, 29: 464-470

Koch M, Habazettl I, Dehghani F, Korf HW (2008) The rat pineal gland comprises an endocannabinoid system. J Pineal Res 45: 351-360

Korf H W, Wicht H, Snipes R L, Timmermans J P, Paulsen F, Rune G, Baumgart-Vogt E (2008) The dissection course – necessary and indispensable for teaching anatomy to medical students. Ann Anat 190: 16-22

Ono H, Hoshino Y, Yasuo S, Watanabe M, Nakane Y, Murai A, Ebihara S, Korf HW, Yoshimura T (2008) Involvement of thyrotropin in photoperiodic signal transduction in mice. Proc Natl Acad Sci 105: 18238-18242

Schomerus C, Korf H W, Laedtke E, Moret F, Zhang Q, Wicht H (2008) Nocturnal behavior and rhythmic period gene expression in a lancelet, Branchiostoma lanceolatum. J Biol Rhythms 23: 170-181

Spahn A, Blondeau N, Heurteaux C, Dehghani F, Rami A (2008) Concomitant Transitory Up-Regulation of X-Linked Inhibitor of Apoptosis Protein (XIAP) and the Heterogeneous Nuclear Ribonucleoprotein C1-C2 in Surviving Cells During Neuronal Apoptosis. Neurochem Res. 33:1859-1868

Vogt C, Hailer NP, Ghadban C, Korf HW, Dehghani F (2008) Successful inhibition of excitotoxic neuronal damage and microglial activation after delayed application of interleukin-1 receptor antagonist. J Neurosci Res 86: 3314-3321

Yasuo S, von Gall C, Weaver DR, Korf HW (2008) Rhythmic expression of clock genes in the ependymal cell layer of the third ventricle of rodents is independent of melatonin signaling. Eur J Neurosci, 28: 2443-2450

Zander J, Besier S, Saum SH, Dehghani F, Loitsch S, Brade V, Wichelhaus TA (2008) Influence of dTMP on the phenotypic appearance and intracellular persistence of Staphylococcus aureus. Infect Immun 76: 1333-1339


Ackermann K, Dehghani F, Bux R, Kauert G, Stehle JH (2007) Day-night expression patterns of clock genes in the human pineal gland. J Pineal Res 43: 185-194

Althaus J, Siegelin MD, Dehghani F, Cilenti L, Zervos AS, Rami A (2007) The serine protease Omi/HtrA2 is involved in XIAP cleavage and in neuronal cell death following focal cerebral ischemia/reperfusion. Neurochem Int 50: 172-180

Anraku T, Takagi T, Nakao N, Watanabe M, Yasuo S, Katou Y, Ueda Y, Murai A, Iigo M, Ebihara S, Yoshimura T (2007) Photoperiodic changes in hypothalamic insulin receptor gene expression are regulated by gonadal testosterone. Brain Res 1163: 86-90

Aoki Y, Ono H, Yasuo S, Masuda T, Yoshimura T, Ebihara S, Iigo M, Yanagisawa T (2007) Molecular evolution of prepro-thyrotropin-releasing hormone in the chicken (Gallus gallus) and its expression in the brain. Zoolog Sci 24: 686-692

Dinet V, Korf HW (2007) Impact of melatonin receptors on pCREB and clock-gene protein levels in the murine retina. Cell Tissue Res 330: 29-34

Dinet V, Ansari N, Torres-Farfan C, Korf HW (2007) Clock gene expression in the retina of melatonin-proficient (C3H) and melatonin-deficient (C57BL) mice. J Pineal Res 42: 83-91

Von Gall, C (2007) Die Pars tuberalis als Modellsystem eines Melatonin-abhängigen peripheren circardianen Oscillators. Peschke E (ed) Endokrinologie III. Abh Sächs Akad Wiss zu Leipzig, Vol 64/4. Hirzel, Stuttgart/Leipzig, 81-91

Korf H W (2007) Welcome address to the 102nd congress of the Anatomische Gesellschaft in Gießen, Germany, March 30-April 2 2007, Ann Anat 189: 533-534

Korf HW (2007) Einheit und Vielheit - unity and plurality. Ann Anat 189: 535-548

Kreutz S, Koch M, Ghadban C, Korf H-W, Dehghani F (2007) Cannabinoids and secondary neuronal damage: differential effects of THC, AEA and 2-AG on activated microglial cells and degenerating neurons in excitotoxically lesioned rat organotypic hippocampal slice cultures. Exp Neurol 203: 246-257

Lipp M, Brandt C, Dehghani F, Kwidzinski E, Bechmann I(2007) PD-L1 (B7-H1) regulation in zones of axonal degeneration. Neurosci Lett 425: 156-161

Maronde E, Pfeffer M, Glass Y, Stehle JH (2007) Transcription factor dynamics in pineal gland and liver of the Syrian hamster (Mesocricetus auratus) adapts to prevailing photoperiod. J Pineal Res 43: 16-24

Nakao N, Yasuo S, Nishimura A, Yamamura T, Watanabe T, Anraku T, Okano T, Fukada Y, Sharp PJ, Ebihara S, Yoshimura T (2007) Circadian clock gene regulation of steroidogenic acute regulatory protein gene expression in preovulatory ovarian follicles. Endocrinology 148: 3031-3038

Niederberger E, Ehnert C, Gao W, Coste O, Schmidtko A, Popp L, von Gall C, Korf HW, Tegeder I, Geisslinger G (2007) The impact of CREB and its phosphorylation at Ser142 on inflammatory nociception. Biochem Biophys Res Commun 362: 75-80

Schomerus C (2007) Adrenerge und cholinerge Signalverarbeitung im Pinealorgan von Säugetieren. Peschke E (ed) Endokrinologie III. Abh, Sächs Akad Wiss zu Leipzig, Hirzel, Stuttgart/Leipzig, 64: 72-80

Takagi T, Yamamura T, Anraku T, Yasuo S, Nakao N, Watanabe M, Iigo M, Ebihara S, Yoshimura T (2007) Involvement of transforming growth factor alpha in the photoperiodic regulation of reproduction in birds. Endocrinology 148: 2788-2792

Watanabe T, Yamamura T, Watanabe M, Yasuo S, Nakao N, Dawson A, Ebihara S, Yoshimura T (2007) Hypothalamic expression of thyroid hormone-activating and -inactivating enzyme genes in relation to photorefractoriness in birds and mammals. Am J Physiol Regul Integr Comp Physiol 292: 568-572

Yasuo S, Watanabe M, Iigo M, Nakamura TJ, Watanabe T, Takagi T, Ono H, Ebihara S, Yoshimura T (2007) Differential response of type 2 deiodinase gene expression to photoperiod between photoperiodic Fischer 344 and nonphotoperiodic Wistar rats. J Physiol Regul Integr Comp Physiol 292: 1315-1319

Yasuo S, Takashi Y, Ebihara S, Korf HW (2007) Temporal dynamics of type 2 deiodinase expression after melatonin injections in Syrian hamsters. Endocrinology 148: 4385-4392


Koch M, Dehghani F, Habazettl I, Schomerus C, Korf HW (2006) Cannabinoids attenuate norepinephrine-induced melatonin biosynthesis in the rat pineal gland by reducing arylalkylamine N-acetyltransferase activity without involvement of cannabinoid receptors. J Neurochem 98: 267-278

Kreutz S, Korf H-W, Schubert-Zsilavecz M (2006) Selektive Cannabinoid-Rezeptor-Antagonisten: Neue Therapieoption zur Behandlung von Adipositas. Pharm Unserer Zeit 6: 512-520

Mishra SK, Braun N, Shukla V, Fullgrabe M, Schomerus C, Korf HW, Gachet C, Ikehara Y, Sevigny J, Robson SC, Zimmermann H (2006) Extracellular nucleotide signaling in adult neural stem cells: synergism with growth factor-mediated cellular proliferation. Development 133: 675-684

Oest TM, Dehghani F, Korf HW, Hailer NP (2006) The immunosuppressant mycophenolate mofetil improves preservation of the perforant path in organotypic hippocampal slice cultures: a retrograde tracing study. Hippocampus 16: 437-442

Torres-Farfan C, Seron-Ferre M, Dinet V, Korf HW (2006) Immunocytochemical demonstration of day/night changes of clock gene protein levels in the murine adrenal gland: differences between melatonin-proficient (C3H) and melatonin-deficient (C57BL) mice. J Pineal Res 40: 64-70